BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 32477121)

  • 21. MDMX under stress: the MDMX-MDM2 complex as stress signals hub.
    de Polo A; Vivekanandan V; Little JB; Yuan ZM
    Transl Cancer Res; 2016 Dec; 5(6):725-732. PubMed ID: 30319942
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mdm2 ligase dead mutants did not act in a dominant negative manner to re-activate p53, but promoted tumor cell growth.
    Swaroop M; Sun Y
    Anticancer Res; 2003; 23(4):3167-74. PubMed ID: 12926050
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mouse double minute 2 associates with chromatin in the presence of p53 and is released to facilitate activation of transcription.
    White DE; Talbott KE; Arva NC; Bargonetti J
    Cancer Res; 2006 Apr; 66(7):3463-70. PubMed ID: 16585169
    [TBL] [Abstract][Full Text] [Related]  

  • 24. SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination.
    Lee MH; Lee SW; Lee EJ; Choi SJ; Chung SS; Lee JI; Cho JM; Seol JH; Baek SH; Kim KI; Chiba T; Tanaka K; Bang OS; Chung CH
    Nat Cell Biol; 2006 Dec; 8(12):1424-31. PubMed ID: 17086174
    [TBL] [Abstract][Full Text] [Related]  

  • 25. DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.
    Soares J; Espadinha M; Raimundo L; Ramos H; Gomes AS; Gomes S; Loureiro JB; Inga A; Reis F; Gomes C; Santos MMM; Saraiva L
    Mol Oncol; 2017 Jun; 11(6):612-627. PubMed ID: 28296148
    [TBL] [Abstract][Full Text] [Related]  

  • 26. RNF12 promotes p53-dependent cell growth suppression and apoptosis by targeting MDM2 for destruction.
    Gao K; Wang C; Jin X; Xiao J; Zhang E; Yang X; Wang D; Huang H; Yu L; Zhang P
    Cancer Lett; 2016 May; 375(1):133-141. PubMed ID: 26926424
    [TBL] [Abstract][Full Text] [Related]  

  • 27. p53: An Attractive Therapeutic Target for Cancer.
    Patel KR; Patel HD
    Curr Med Chem; 2020; 27(22):3706-3734. PubMed ID: 31223076
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination.
    Wei J; Yang Y; Lu M; Xu L; Liu F; Yuan Z; Bao Q; Jiang Z; Xu X; Guo X; Zhang X; You Q; Sun H
    Anticancer Agents Med Chem; 2015; 16(2):174-89. PubMed ID: 26343143
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Small molecule antagonists of the MDM2 oncoprotein as anticancer agents.
    Buolamwini JK; Addo J; Kamath S; Patil S; Mason D; Ores M
    Curr Cancer Drug Targets; 2005 Feb; 5(1):57-68. PubMed ID: 15720190
    [TBL] [Abstract][Full Text] [Related]  

  • 30. MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner.
    Feng FY; Zhang Y; Kothari V; Evans JR; Jackson WC; Chen W; Johnson SB; Luczak C; Wang S; Hamstra DA
    Neoplasia; 2016 Apr; 18(4):213-22. PubMed ID: 27108384
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
    Carr MI; Roderick JE; Zhang H; Woda BA; Kelliher MA; Jones SN
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):15024-15029. PubMed ID: 27956626
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.
    Wang H; Cai S; Bailey BJ; Reza Saadatzadeh M; Ding J; Tonsing-Carter E; Georgiadis TM; Zachary Gunter T; Long EC; Minto RE; Gordon KR; Sen SE; Cai W; Eitel JA; Waning DL; Bringman LR; Wells CD; Murray ME; Sarkaria JN; Gelbert LM; Jones DR; Cohen-Gadol AA; Mayo LD; Shannon HE; Pollok KE
    J Neurosurg; 2017 Feb; 126(2):446-459. PubMed ID: 27177180
    [TBL] [Abstract][Full Text] [Related]  

  • 33. MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?
    Azer SA
    J Clin Med; 2018 Mar; 7(4):. PubMed ID: 29584707
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Efficient activation of p53 pathway in A549 cells exposed to L2, a novel compound targeting p53-MDM2 interaction.
    Zhang L; Zhang J; Hu C; Cao J; Zhou X; Hu Y; He Q; Yang B
    Anticancer Drugs; 2009 Jul; 20(6):416-24. PubMed ID: 19579266
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.
    Wu L; Levine AJ
    Mol Med; 1997 Jul; 3(7):441-51. PubMed ID: 9260156
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells.
    Geng QQ; Dong DF; Chen NZ; Wu YY; Li EX; Wang J; Wang SM
    Int J Oncol; 2013 Dec; 43(6):1935-42. PubMed ID: 24126697
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting Post-Translational Regulation of p53 in Colorectal Cancer by Exploiting Vulnerabilities in the p53-MDM2 Axis.
    Lai CW; Xie C; Raufman JP; Xie G
    Cancers (Basel); 2022 Jan; 14(1):. PubMed ID: 35008383
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Recent advances of p53-MDM2 small molecule inhibitors (2011-present).
    Lv PC; Sun J; Zhu HL
    Curr Med Chem; 2015; 22(5):618-26. PubMed ID: 25439588
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The past, present and future of potential small-molecule drugs targeting p53-MDM2/MDMX for cancer therapy.
    Liu Y; Wang X; Wang G; Yang Y; Yuan Y; Ouyang L
    Eur J Med Chem; 2019 Aug; 176():92-104. PubMed ID: 31100649
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry.
    Simerzin A; Zorde-Khvalevsky E; Rivkin M; Adar R; Zucman-Rossi J; Couchy G; Roskams T; Govaere O; Oren M; Giladi H; Galun E
    Hepatology; 2016 Nov; 64(5):1623-1636. PubMed ID: 27302319
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.