130 related articles for article (PubMed ID: 32480171)
1. Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening.
Han J; Tian Y; Yu L; Zhang Q; Xu X; Zhang Y; Wang J; Ma Z; Bian J; Luo C; Jiang H; Chen K; Zhao Y; Li Z; Ding H
Bioorg Chem; 2020 Aug; 101():103962. PubMed ID: 32480171
[TBL] [Abstract][Full Text] [Related]
2. The oncogenic role of ubiquitin specific peptidase (USP8) and its signaling pathways targeting for cancer therapeutics.
Islam MT; Chen F; Chen H
Arch Biochem Biophys; 2021 Apr; 701():108811. PubMed ID: 33600786
[TBL] [Abstract][Full Text] [Related]
3. Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression.
Tian Y; Liu K; Liu R; Qiu Z; Xu Y; Wei W; Xu X; Wang J; Ding H; Li Z; Bian J
J Med Chem; 2022 Jul; 65(13):8914-8932. PubMed ID: 35786929
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes.
Colombo M; Vallese S; Peretto I; Jacq X; Rain JC; Colland F; Guedat P
ChemMedChem; 2010 Apr; 5(4):552-8. PubMed ID: 20186914
[TBL] [Abstract][Full Text] [Related]
5. Inhibiting USP8 overcomes hepatocellular carcinoma resistance via suppressing receptor tyrosine kinases.
Zhu Y; Xu J; Hu W; Wang F; Zhou Y; Gong W; Xu W
Aging (Albany NY); 2021 Jun; 13(11):14999-15012. PubMed ID: 34081623
[TBL] [Abstract][Full Text] [Related]
6. Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.
Tan L; Shan H; Han C; Zhang Z; Shen J; Zhang X; Xiang H; Lu K; Qi C; Li Y; Zhuang G; Chen G; Tan L
J Med Chem; 2022 Oct; 65(20):13645-13659. PubMed ID: 36221183
[TBL] [Abstract][Full Text] [Related]
7. Ubiquitin-specific peptidase 8 regulates the trafficking and stability of the human organic anion transporter 1.
Zhang J; Liu C; You G
Biochim Biophys Acta Gen Subj; 2020 Dec; 1864(12):129701. PubMed ID: 32818533
[TBL] [Abstract][Full Text] [Related]
8. VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8.
Smith GA; Fearnley GW; Abdul-Zani I; Wheatcroft SB; Tomlinson DC; Harrison MA; Ponnambalam S
Traffic; 2016 Jan; 17(1):53-65. PubMed ID: 26459808
[TBL] [Abstract][Full Text] [Related]
9. Ubiquitin-specific protease 8 (USP8/UBPy): a prototypic multidomain deubiquitinating enzyme with pleiotropic functions.
Dufner A; Knobeloch KP
Biochem Soc Trans; 2019 Dec; 47(6):1867-1879. PubMed ID: 31845722
[TBL] [Abstract][Full Text] [Related]
10. USP8 modulates ubiquitination of LRIG1 for Met degradation.
Oh YM; Lee SB; Choi J; Suh HY; Shim S; Song YJ; Kim B; Lee JM; Oh SJ; Jeong Y; Cheong KH; Song PH; Kim KA
Sci Rep; 2014 May; 4():4980. PubMed ID: 24828152
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Adrenocorticotropic Hormone Production and Tumorous Corticotroph Cell Growth in AtT20 Cells.
Jian FF; Li YF; Chen YF; Jiang H; Chen X; Zheng LL; Zhao Y; Wang WQ; Ning G; Bian LG; Sun QF
Chin Med J (Engl); 2016 Sep; 129(17):2102-8. PubMed ID: 27569239
[TBL] [Abstract][Full Text] [Related]
12. The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.
Yeates EF; Tesco G
J Biol Chem; 2016 Jul; 291(30):15753-66. PubMed ID: 27302062
[TBL] [Abstract][Full Text] [Related]
13. USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels.
Kerrisk Campbell M; Sheng M
J Neurosci; 2018 Jun; 38(23):5289-5301. PubMed ID: 29735556
[TBL] [Abstract][Full Text] [Related]
14. Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.
Kakihara K; Asamizu K; Moritsugu K; Kubo M; Kitaguchi T; Endo A; Kidera A; Ikeguchi M; Kato A; Komada M; Fukushima T
Commun Biol; 2021 Nov; 4(1):1272. PubMed ID: 34750505
[TBL] [Abstract][Full Text] [Related]
15. Ubiquitin-specific protease 8 inhibitor suppresses adrenocorticotropic hormone production and corticotroph tumor cell proliferation.
Kageyama K; Asari Y; Sugimoto Y; Niioka K; Daimon M
Endocr J; 2020 Feb; 67(2):177-184. PubMed ID: 31666445
[TBL] [Abstract][Full Text] [Related]
16. Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8.
Wu X; Yen L; Irwin L; Sweeney C; Carraway KL
Mol Cell Biol; 2004 Sep; 24(17):7748-57. PubMed ID: 15314180
[TBL] [Abstract][Full Text] [Related]
17. The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
Sun J; Hu Q; Peng H; Peng C; Zhou L; Lu J; Huang C
J Biol Chem; 2018 May; 293(21):8275-8284. PubMed ID: 29626091
[TBL] [Abstract][Full Text] [Related]
18. Identification of chemicals breaking the USP8 interaction with its endocytic substrate CHMP1B.
Journet A; Barette C; Aubry L; Soleilhac E; Fauvarque MO
SLAS Discov; 2022 Oct; 27(7):395-404. PubMed ID: 35995394
[TBL] [Abstract][Full Text] [Related]
19. Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates β-Cell Mitophagy.
Pearson G; Chai B; Vozheiko T; Liu X; Kandarpa M; Piper RC; Soleimanpour SA
Diabetes; 2018 Feb; 67(2):265-277. PubMed ID: 29180353
[TBL] [Abstract][Full Text] [Related]
20. Ubiquitin-Specific Protease 8 Mutant Corticotrope Adenomas Present Unique Secretory and Molecular Features and Shed Light on the Role of Ubiquitylation on ACTH Processing.
Sesta A; Cassarino MF; Terreni M; Ambrogio AG; Libera L; Bardelli D; Lasio G; Losa M; Pecori Giraldi F
Neuroendocrinology; 2020; 110(1-2):119-129. PubMed ID: 31280266
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
