147 related articles for article (PubMed ID: 32491252)
1. Discovery of novel N-aryl pyrrothine derivatives as bacterial RNA polymerase inhibitors.
Huang MH; Kong B; Meng JY; Lv YB; Peng YF; Chen YP; Tan XD
Chem Biol Drug Des; 2020 Nov; 96(5):1262-1271. PubMed ID: 32491252
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of novel hybrids of N-aryl pyrrothine-base α-pyrone as bacterial RNA polymerase inhibitors.
Tan X; Huang M; Nian S; Peng Y; Qin J; Kong B; Duan X
Bioorg Med Chem Lett; 2020 Jun; 30(11):127146. PubMed ID: 32249118
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel bacterial RNA polymerase inhibitors: pharmacophore-based virtual screening and hit optimization.
Hinsberger S; Hüsecken K; Groh M; Negri M; Haupenthal J; Hartmann RW
J Med Chem; 2013 Nov; 56(21):8332-8. PubMed ID: 24112046
[TBL] [Abstract][Full Text] [Related]
4. Novel small molecule inhibitors targeting the "switch region" of bacterial RNAP: structure-based optimization of a virtual screening hit.
Sahner JH; Groh M; Negri M; Haupenthal J; Hartmann RW
Eur J Med Chem; 2013 Jul; 65():223-31. PubMed ID: 23711833
[TBL] [Abstract][Full Text] [Related]
5. A detailed study of antibacterial 3-acyltetramic acids and 3-acylpiperidine-2,4-diones.
Jeong YC; Bikadi Z; Hazai E; Moloney MG
ChemMedChem; 2014 Aug; 9(8):1826-37. PubMed ID: 24838989
[TBL] [Abstract][Full Text] [Related]
6. Derivatives of aryl-4-guanidinomethylbenzoate and N-aryl-4-guanidinomethylbenzamide as new antibacterial agents: synthesis and bioactivity.
Yu WY; Yang LX; Xie JS; Zhou L; Jiang XY; Zhu DX; Muramatsu M; Wang MW
Acta Pharmacol Sin; 2008 Feb; 29(2):267-77. PubMed ID: 18215358
[TBL] [Abstract][Full Text] [Related]
7. Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors.
Elgaher WA; Sharma KK; Haupenthal J; Saladini F; Pires M; Real E; Mély Y; Hartmann RW
J Med Chem; 2016 Aug; 59(15):7212-22. PubMed ID: 27339173
[TBL] [Abstract][Full Text] [Related]
8. Novel rapidly diversifiable antimicrobial RNA polymerase switch region inhibitors with confirmed mode of action in Haemophilus influenzae.
Buurman ET; Foulk MA; Gao N; Laganas VA; McKinney DC; Moustakas DT; Rose JA; Shapiro AB; Fleming PR
J Bacteriol; 2012 Oct; 194(20):5504-12. PubMed ID: 22843845
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antibacterial bioactivities of cationic deacetyl linezolid amphiphiles.
Bai PY; Qin SS; Chu WC; Yang Y; Cui DY; Hua YG; Yang QQ; Zhang E
Eur J Med Chem; 2018 Jul; 155():925-945. PubMed ID: 29966917
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, molecular docking and biological evaluation of metronidazole derivatives containing piperazine skeleton as potential antibacterial agents.
Wang SF; Yin Y; Qiao F; Wu X; Sha S; Zhang L; Zhu HL
Bioorg Med Chem; 2014 Apr; 22(8):2409-15. PubMed ID: 24680059
[TBL] [Abstract][Full Text] [Related]
11. Inhibitors of bacterial RNA polymerase transcription complex.
Wenholz DS; Miller M; Dawson C; Bhadbhade M; Black DS; Griffith R; Dinh H; Cain A; Lewis P; Kumar N
Bioorg Chem; 2022 Jan; 118():105481. PubMed ID: 34801947
[TBL] [Abstract][Full Text] [Related]
12. Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.
Jakopin Ž; Ilaš J; Barančoková M; Brvar M; Tammela P; Sollner Dolenc M; Tomašič T; Kikelj D
Eur J Med Chem; 2017 Apr; 130():171-184. PubMed ID: 28246042
[TBL] [Abstract][Full Text] [Related]
13. Affinity Selection-Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor.
Walker SS; Degen D; Nickbarg E; Carr D; Soriano A; Mandal M; Painter RE; Sheth P; Xiao L; Sher X; Murgolo N; Su J; Olsen DB; Ebright RH; Young K
ACS Chem Biol; 2017 May; 12(5):1346-1352. PubMed ID: 28323406
[TBL] [Abstract][Full Text] [Related]
14. Evaluating the activity of the RNA polymerase inhibitor myxopyronin B against Staphylococcus aureus.
Moy TI; Daniel A; Hardy C; Jackson A; Rehrauer O; Hwang YS; Zou D; Nguyen K; Silverman JA; Li Q; Murphy C
FEMS Microbiol Lett; 2011 Jun; 319(2):176-9. PubMed ID: 21477256
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationship of amidine derivatives of 3,4-ethylenedioxythiophene as novel antibacterial agents.
Stolić I; Čipčić Paljetak H; Perić M; Matijašić M; Stepanić V; Verbanac D; Bajić M
Eur J Med Chem; 2015 Jan; 90():68-81. PubMed ID: 25461312
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of new tyrosyl-tRNA synthetase inhibitors as antibacterial agents based on a N2-(arylacetyl)glycinanilide scaffold.
Xiao ZP; Wei W; Wang PF; Shi WK; Zhu N; Xie MQ; Sun YW; Li LX; Xie YX; Zhu LS; Tang N; Ouyang H; Li XH; Wang GC; Zhu HL
Eur J Med Chem; 2015 Sep; 102():631-8. PubMed ID: 26318069
[TBL] [Abstract][Full Text] [Related]
17. New target for inhibition of bacterial RNA polymerase: 'switch region'.
Srivastava A; Talaue M; Liu S; Degen D; Ebright RY; Sineva E; Chakraborty A; Druzhinin SY; Chatterjee S; Mukhopadhyay J; Ebright YW; Zozula A; Shen J; Sengupta S; Niedfeldt RR; Xin C; Kaneko T; Irschik H; Jansen R; Donadio S; Connell N; Ebright RH
Curr Opin Microbiol; 2011 Oct; 14(5):532-43. PubMed ID: 21862392
[TBL] [Abstract][Full Text] [Related]
18. Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitors.
Stana A; Vodnar DC; Marc G; Benedec D; Tiperciuc B; Tamaian R; Oniga O
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):898-908. PubMed ID: 30938216
[TBL] [Abstract][Full Text] [Related]
19. Frequency, spectrum, and nonzero fitness costs of resistance to myxopyronin in Staphylococcus aureus.
Srivastava A; Degen D; Ebright YW; Ebright RH
Antimicrob Agents Chemother; 2012 Dec; 56(12):6250-5. PubMed ID: 23006749
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
Fedorowicz J; Sączewski J; Konopacka A; Waleron K; Lejnowski D; Ciura K; Tomašič T; Skok Ž; Savijoki K; Morawska M; Gilbert-Girard S; Fallarero A
Eur J Med Chem; 2019 Oct; 179():576-590. PubMed ID: 31279292
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]