BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 32493844)

  • 1. LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling.
    Mancini A; Howard SR; Marelli F; Cabrera CP; Barnes MR; Sternberg MJ; Leprovots M; Hadjidemetriou I; Monti E; David A; Wehkalampi K; Oleari R; Lettieri A; Vezzoli V; Vassart G; Cariboni A; Bonomi M; Garcia MI; Guasti L; Dunkel L
    JCI Insight; 2020 Jun; 5(11):. PubMed ID: 32493844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. EAP1 regulation of GnRH promoter activity is important for human pubertal timing.
    Mancini A; Howard SR; Cabrera CP; Barnes MR; David A; Wehkalampi K; Heger S; Lomniczi A; Guasti L; Ojeda SR; Dunkel L
    Hum Mol Genet; 2019 Apr; 28(8):1357-1368. PubMed ID: 30608578
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of LGR4/GPR48 causes severe neonatal salt wasting due to disrupted WNT signaling altering adrenal zonation.
    Lucas C; Sauter KS; Steigert M; Mallet D; Wilmouth J; Olabe J; Plotton I; Morel Y; Aeberli D; Wagner F; Clevers H; Pandey AV; Val P; Roucher-Boulez F; Flück CE
    J Clin Invest; 2023 Feb; 133(4):. PubMed ID: 36538378
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
    Xu P; Dang Y; Wang L; Liu X; Ren X; Gu J; Liu M; Dai X; Ye X
    Cancer Lett; 2016 Dec; 383(2):161-170. PubMed ID: 27693558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis.
    Qian Y; Liu S; Guan Y; Pan H; Guan X; Qiu Z; Li L; Gao N; Zhao Y; Li X; Lu Y; Liu M; Li D
    Development; 2013 Apr; 140(8):1751-61. PubMed ID: 23533175
    [TBL] [Abstract][Full Text] [Related]  

  • 6. R-spondin 2-LGR4 system regulates growth, migration and invasion, epithelial-mesenchymal transition and stem-like properties of tongue squamous cell carcinoma via Wnt/β-catenin signaling.
    Zhang L; Song Y; Ling Z; Li Y; Ren X; Yang J; Wang Z; Xia J; Zhang W; Cheng B
    EBioMedicine; 2019 Jun; 44():275-288. PubMed ID: 31097406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.
    Carmon KS; Gong X; Yi J; Thomas A; Liu Q
    Proc Natl Acad Sci U S A; 2014 Apr; 111(13):E1221-9. PubMed ID: 24639526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases.
    Park S; Wu L; Tu J; Yu W; Toh Y; Carmon KS; Liu QJ
    Sci Signal; 2020 Dec; 13(660):. PubMed ID: 33262293
    [No Abstract]   [Full Text] [Related]  

  • 9. IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty.
    Howard SR; Guasti L; Ruiz-Babot G; Mancini A; David A; Storr HL; Metherell LA; Sternberg MJ; Cabrera CP; Warren HR; Barnes MR; Quinton R; de Roux N; Young J; Guiochon-Mantel A; Wehkalampi K; André V; Gothilf Y; Cariboni A; Dunkel L
    EMBO Mol Med; 2016 Jun; 8(6):626-42. PubMed ID: 27137492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.
    Wang Y; Dong J; Li D; Lai L; Siwko S; Li Y; Liu M
    Stem Cells; 2013 Sep; 31(9):1921-31. PubMed ID: 23712846
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.
    Yue Z; Yuan Z; Zeng L; Wang Y; Lai L; Li J; Sun P; Xue X; Qi J; Yang Z; Zheng Y; Fang Y; Li D; Siwko S; Li Y; Luo J; Liu M
    FASEB J; 2018 May; 32(5):2422-2437. PubMed ID: 29269400
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Genetic Basis of Delayed Puberty.
    Howard SR; Dunkel L
    Neuroendocrinology; 2018; 106(3):283-291. PubMed ID: 28926843
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Delayed puberty in spontaneously hypertensive rats involves a primary ovarian failure independent of the hypothalamic KiSS-1/GPR54/GnRH system.
    Pinilla L; Castellano JM; Romero M; Tena-Sempere M; Gaytán F; Aguilar E
    Endocrinology; 2009 Jun; 150(6):2889-97. PubMed ID: 19228890
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
    Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ
    J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.
    van Andel H; Ren Z; Koopmans I; Joosten SP; Kocemba KA; de Lau W; Kersten MJ; de Bruin AM; Guikema JE; Clevers H; Spaargaren M; Pals ST
    Proc Natl Acad Sci U S A; 2017 Jan; 114(2):376-381. PubMed ID: 28028233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.
    Pan H; Cui H; Liu S; Qian Y; Wu H; Li L; Guan Y; Guan X; Zhang L; Fan HY; Ma Y; Li R; Liu M; Li D
    Endocrinology; 2014 Sep; 155(9):3624-37. PubMed ID: 24877628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lgr4 promotes glioma cell proliferation through activation of Wnt signaling.
    Yu CY; Liang GB; Du P; Liu YH
    Asian Pac J Cancer Prev; 2013; 14(8):4907-11. PubMed ID: 24083766
    [TBL] [Abstract][Full Text] [Related]  

  • 18. R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
    Ruffner H; Sprunger J; Charlat O; Leighton-Davies J; Grosshans B; Salathe A; Zietzling S; Beck V; Therier M; Isken A; Xie Y; Zhang Y; Hao H; Shi X; Liu D; Song Q; Clay I; Hintzen G; Tchorz J; Bouchez LC; Michaud G; Finan P; Myer VE; Bouwmeester T; Porter J; Hild M; Bassilana F; Parker CN; Cong F
    PLoS One; 2012; 7(7):e40976. PubMed ID: 22815884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blockade of LGR4 inhibits proliferation and odonto/osteogenic differentiation of stem cells from apical papillae.
    Zhou M; Guo S; Yuan L; Zhang Y; Zhang M; Chen H; Lu M; Yang J; Ma J
    J Mol Histol; 2017 Dec; 48(5-6):389-401. PubMed ID: 28986711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lgr4 promotes aerobic glycolysis and differentiation in osteoblasts via the canonical Wnt/β-catenin pathway.
    Yang YY; Zhou YM; Xu JZ; Sun LH; Tao B; Wang WQ; Wang JQ; Zhao HY; Liu JM
    J Bone Miner Res; 2021 Aug; 36(8):1605-1620. PubMed ID: 33950533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.