BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 32494799)

  • 1. Grafting multi-maleimides on antisense oligonucleotide to enhance its cellular uptake and gene silencing capability.
    Guo Y; Zhang J; Pan G; Choi CHJ; Wang P; Li Y; Zhu X; Zhang C
    Chem Commun (Camb); 2020 Jul; 56(54):7439-7442. PubMed ID: 32494799
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficient in vivo delivery of antisense oligonucleotide to choroid plexus.
    Piao W; Nishina K; Yoshida-Tanaka K; Kuwahara H; Nishina T; Sakata M; Mizusawa H; Yokota T
    J Med Dent Sci; 2013 Mar; 60(1):9-16. PubMed ID: 23917958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gene silencing using a conjugate comprising Tat peptide and antisense oligonucleotide with phosphorothioate backbones.
    Maegawa Y; Mochizuki S; Miyamoto N; Sakurai K
    Bioorg Med Chem Lett; 2016 Feb; 26(4):1276-8. PubMed ID: 26774656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes.
    Tanowitz M; Hettrick L; Revenko A; Kinberger GA; Prakash TP; Seth PP
    Nucleic Acids Res; 2017 Dec; 45(21):12388-12400. PubMed ID: 29069408
    [TBL] [Abstract][Full Text] [Related]  

  • 5. On the role of methacrylic acid copolymers in the intracellular delivery of antisense oligonucleotides.
    Yessine MA; Meier C; Petereit HU; Leroux JC
    Eur J Pharm Biopharm; 2006 May; 63(1):1-10. PubMed ID: 16364618
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Topical gene silencing by iontophoretic delivery of an antisense oligonucleotide-dendrimer nanocomplex: the proof of concept in a skin cancer mouse model.
    Venuganti VV; Saraswathy M; Dwivedi C; Kaushik RS; Perumal OP
    Nanoscale; 2015 Mar; 7(9):3903-14. PubMed ID: 25436837
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A naked antisense oligonucleotide with phosphorothioate linkages is taken up intracellularly more efficiently but functions less effectively.
    Takahashi M; Seki M; Nashimoto M
    Biochem Biophys Res Commun; 2021 Oct; 573():140-144. PubMed ID: 34411896
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides.
    Wada S; Yasuhara H; Wada F; Sawamura M; Waki R; Yamamoto T; Harada-Shiba M; Obika S
    J Control Release; 2016 Mar; 226():57-65. PubMed ID: 26855051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotides.
    Wang S; Sun H; Tanowitz M; Liang XH; Crooke ST
    Nucleic Acids Res; 2017 May; 45(9):5309-5322. PubMed ID: 28379543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of multivalent fatty acid-conjugated antisense oligonucleotides: Cell internalization, physical properties, and in vitro and in vivo activities.
    Tanaka Y; Tanioku Y; Nakayama T; Aso K; Yamaguchi T; Kamada H; Obika S
    Bioorg Med Chem; 2023 Mar; 81():117192. PubMed ID: 36780806
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel anionic dendrimer for improved cellular delivery of antisense oligonucleotides.
    Hussain M; Shchepinov M; Sohail M; Benter IF; Hollins AJ; Southern EM; Akhtar S
    J Control Release; 2004 Sep; 99(1):139-55. PubMed ID: 15342187
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of 2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modification on activity of gapmer antisense oligonucleotides containing 2',4'-constrained 2'-O-ethyl nucleic acid.
    Pandey SK; Nowak A; Perkins J; Ferng A; Prakash TP
    Bioorg Med Chem Lett; 2015 Apr; 25(8):1688-1691. PubMed ID: 25804718
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids.
    Zelphati O; Szoka FC
    Pharm Res; 1996 Sep; 13(9):1367-72. PubMed ID: 8893276
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antisense oligonucleotides: target validation and development of systemically delivered therapeutic nanoparticles.
    Zhang C; Pei J; Kumar D; Sakabe I; Boudreau HE; Gokhale PC; Kasid UN
    Methods Mol Biol; 2007; 361():163-85. PubMed ID: 17172711
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for a specific intracellular localization of an antisense oligonucleotide in k562 cells.
    Vasconcelos MH; Maia LF; Sousa C; Beleza SS; Guimarães JE
    J Pharmacol Sci; 2005 Sep; 99(1):105-8. PubMed ID: 16141637
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Annexin A2 facilitates endocytic trafficking of antisense oligonucleotides.
    Wang S; Sun H; Tanowitz M; Liang XH; Crooke ST
    Nucleic Acids Res; 2016 Sep; 44(15):7314-30. PubMed ID: 27378781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular uptake mechanism for oligonucleotides: involvement of endocytosis in the uptake of phosphodiester oligonucleotides by a human colorectal adenocarcinoma cell line, HCT-15.
    Nakai D; Seita T; Terasaki T; Iwasa S; Shoji Y; Mizushima Y; Sugiyama Y
    J Pharmacol Exp Ther; 1996 Sep; 278(3):1362-72. PubMed ID: 8819524
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle.
    Prakash TP; Mullick AE; Lee RG; Yu J; Yeh ST; Low A; Chappell AE; Østergaard ME; Murray S; Gaus HJ; Swayze EE; Seth PP
    Nucleic Acids Res; 2019 Jul; 47(12):6029-6044. PubMed ID: 31127296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular and cellular barriers limiting the effectiveness of antisense oligonucleotides.
    Roth CM
    Biophys J; 2005 Oct; 89(4):2286-95. PubMed ID: 16055530
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity.
    Liang XH; Shen W; Sun H; Kinberger GA; Prakash TP; Nichols JG; Crooke ST
    Nucleic Acids Res; 2016 May; 44(8):3892-907. PubMed ID: 26945041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.