These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 32495222)

  • 1. Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inhibition in vitro.
    Brandstetter G; Blatt S; Goldschmitt J; Taylor L; Heymann P; Al-Nawas B; Ziebart T
    Clin Oral Investig; 2021 Jan; 25(1):295-310. PubMed ID: 32495222
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular Uptake of MCT1 Inhibitors AR-C155858 and AZD3965 and Their Effects on MCT-Mediated Transport of L-Lactate in Murine 4T1 Breast Tumor Cancer Cells.
    Guan X; Rodriguez-Cruz V; Morris ME
    AAPS J; 2019 Jan; 21(2):13. PubMed ID: 30617815
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monocarboxylate Transporters MCT1 and MCT4 Regulate Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells.
    Kong SC; Nøhr-Nielsen A; Zeeberg K; Reshkin SJ; Hoffmann EK; Novak I; Pedersen SF
    Pancreas; 2016 Aug; 45(7):1036-47. PubMed ID: 26765963
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In Vitro and In Vivo Efficacy of the Monocarboxylate Transporter 1 Inhibitor AR-C155858 in the Murine 4T1 Breast Cancer Tumor Model.
    Guan X; Bryniarski MA; Morris ME
    AAPS J; 2018 Nov; 21(1):3. PubMed ID: 30397860
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the monocarboxylate transporter MCT2 and lactate dehydrogenase A LDHA in cancer cells with FX-11 and AR-C155858 inhibitors.
    Alobaidi B; Hashimi SM; Alqosaibi AI; AlQurashi N; Alhazmi S
    Eur Rev Med Pharmacol Sci; 2023 Jul; 27(14):6605-6617. PubMed ID: 37522672
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation.
    Hanson DJ; Nakamura S; Amachi R; Hiasa M; Oda A; Tsuji D; Itoh K; Harada T; Horikawa K; Teramachi J; Miki H; Matsumoto T; Abe M
    Oncotarget; 2015 Oct; 6(32):33568-86. PubMed ID: 26384349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.
    Le Floch R; Chiche J; Marchiq I; Naiken T; Ilc K; Murray CM; Critchlow SE; Roux D; Simon MP; Pouysségur J
    Proc Natl Acad Sci U S A; 2011 Oct; 108(40):16663-8. PubMed ID: 21930917
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucose-dependent growth arrest of leukemia cells by MCT1 inhibition: Feeding Warburg's sweet tooth and blocking acid export as an anticancer strategy.
    Pivovarova AI; MacGregor GG
    Biomed Pharmacother; 2018 Feb; 98():173-179. PubMed ID: 29253765
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets.
    Miranda-Gonçalves V; Honavar M; Pinheiro C; Martinho O; Pires MM; Pinheiro C; Cordeiro M; Bebiano G; Costa P; Palmeirim I; Reis RM; Baltazar F
    Neuro Oncol; 2013 Feb; 15(2):172-88. PubMed ID: 23258846
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10.
    Ovens MJ; Davies AJ; Wilson MC; Murray CM; Halestrap AP
    Biochem J; 2010 Jan; 425(3):523-30. PubMed ID: 19929853
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein.
    Ovens MJ; Manoharan C; Wilson MC; Murray CM; Halestrap AP
    Biochem J; 2010 Oct; 431(2):217-25. PubMed ID: 20695846
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Vitro and In Vivo Efficacy of AZD3965 and Alpha-Cyano-4-Hydroxycinnamic Acid in the Murine 4T1 Breast Tumor Model.
    Guan X; Morris ME
    AAPS J; 2020 Jun; 22(4):84. PubMed ID: 32529599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas.
    Miranda-Gonçalves V; Granja S; Martinho O; Honavar M; Pojo M; Costa BM; Pires MM; Pinheiro C; Cordeiro M; Bebiano G; Costa P; Reis RM; Baltazar F
    Oncotarget; 2016 Jul; 7(29):46335-46353. PubMed ID: 27331625
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.
    Nancolas B; Sessions RB; Halestrap AP
    Biochem J; 2015 Feb; 466(1):177-88. PubMed ID: 25437897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.
    Lee JY; Lee I; Chang WJ; Ahn SM; Lim SH; Kim HS; Yoo KH; Jung KS; Song HN; Cho JH; Kim SY; Kim KM; Lee S; Kim ST; Park SH; Lee J; Park JO; Park YS; Lim HY; Kang WK
    Oncotarget; 2016 Jul; 7(28):43492-43503. PubMed ID: 27224918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells.
    Izumi H; Takahashi M; Uramoto H; Nakayama Y; Oyama T; Wang KY; Sasaguri Y; Nishizawa S; Kohno K
    Cancer Sci; 2011 May; 102(5):1007-13. PubMed ID: 21306479
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma.
    Khammanivong A; Saha J; Spartz AK; Sorenson BS; Bush AG; Korpela DM; Gopalakrishnan R; Jonnalagadda S; Mereddy VR; O'Brien TD; Drewes LR; Dickerson EB
    Vet Comp Oncol; 2020 Sep; 18(3):324-341. PubMed ID: 31661586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monocarboxylate transporter 1 and 4 inhibitors as potential therapeutics for treating solid tumours: A review with structure-activity relationship insights.
    Puri S; Juvale K
    Eur J Med Chem; 2020 Aug; 199():112393. PubMed ID: 32388280
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells.
    Saulle E; Spinello I; Quaranta MT; Pasquini L; Pelosi E; Iorio E; Castelli G; Chirico M; Pisanu ME; Ottone T; Voso MT; Testa U; Labbaye C
    Front Oncol; 2020; 10():621458. PubMed ID: 33614502
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of transforming growth factor-β1 on functional expression of monocarboxylate transporter 1 in alveolar epithelial A549 cells.
    Uddin M; Kawami M; Yumoto R; Takano M
    Naunyn Schmiedebergs Arch Pharmacol; 2020 May; 393(5):889-896. PubMed ID: 31900520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.