BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 32498476)

  • 1. CaSR Antagonist (Calcilytic) NPS 2143 Hinders the Release of Neuroinflammatory IL-6, Soluble ICAM-1, RANTES, and MCP-2 from Aβ-Exposed Human Cortical Astrocytes.
    Chiarini A; Armato U; Hu P; Dal Prà I
    Cells; 2020 Jun; 9(6):. PubMed ID: 32498476
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25-35 in human cortical astrocytes and neurons-therapeutic relevance to Alzheimer's disease.
    Armato U; Chiarini A; Chakravarthy B; Chioffi F; Pacchiana R; Colarusso E; Whitfield JF; Dal Prà I
    Biochim Biophys Acta; 2013 Oct; 1832(10):1634-52. PubMed ID: 23628734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting Human Astrocytes' Calcium-sensing Receptors for Treatment of Alzheimer's Disease.
    Chiarini A; Armato U; Whitfield JF; Pra ID
    Curr Pharm Des; 2017; 23(33):4990-5000. PubMed ID: 28699522
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes.
    Chiarini A; Armato U; Liu D; Dal Prà I
    Sci Rep; 2017 Apr; 7(1):1277. PubMed ID: 28455519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Aβ peptides-activated calcium-sensing receptor stimulates the production and secretion of vascular endothelial growth factor-A by normoxic adult human cortical astrocytes.
    Dal Prà I; Armato U; Chioffi F; Pacchiana R; Whitfield JF; Chakravarthy B; Gui L; Chiarini A
    Neuromolecular Med; 2014 Dec; 16(4):645-57. PubMed ID: 24948534
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143-Further Implications for Alzheimer's Therapy.
    Chiarini A; Armato U; Gardenal E; Gui L; Dal Prà I
    Front Neurosci; 2017; 11():217. PubMed ID: 28473749
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease.
    Chiarini A; Armato U; Liu D; Dal Prà I
    Front Physiol; 2016; 7():134. PubMed ID: 27199760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preventing the spread of Alzheimer's disease neuropathology: a role for calcilytics?
    Chiarini A; Gardenal E; Whitfield JF; Chakravarthy B; Armato U; Dal Pra I
    Curr Pharm Biotechnol; 2015; 16(8):696-706. PubMed ID: 25941885
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease.
    Dal Prà I; Chiarini A; Pacchiana R; Gardenal E; Chakravarthy B; Whitfield JF; Armato U
    Curr Neuropharmacol; 2014 Jul; 12(4):353-64. PubMed ID: 25342943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.
    Wang XC; Jobin C; Allen JB; Roberts WL; Jaffe GJ
    Invest Ophthalmol Vis Sci; 1999 Feb; 40(2):477-86. PubMed ID: 9950608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytokine regulation of CC and CXC chemokine expression by human astrocytes.
    Oh JW; Schwiebert LM; Benveniste EN
    J Neurovirol; 1999 Feb; 5(1):82-94. PubMed ID: 10190694
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oleanolic acid protects against cognitive decline and neuroinflammation-mediated neurotoxicity by blocking secretory phospholipase A2 IIA-activated calcium signals.
    Zhang L; Xia R; Jia J; Wang L; Li K; Li Y; Zhang J
    Mol Immunol; 2018 Jul; 99():95-103. PubMed ID: 29747052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer's disease progression?
    Dal Prà I; Chiarini A; Armato U
    Neural Regen Res; 2015 Feb; 10(2):213-8. PubMed ID: 25883618
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Calcilytic NPS 2143 Reduces Amyloid Secretion and Increases sAβPPα Release from PSEN1 Mutant iPSC-Derived Neurons.
    Lo Giudice M; Mihalik B; Turi Z; Dinnyés A; Kobolák J
    J Alzheimers Dis; 2019; 72(3):885-899. PubMed ID: 31640098
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Do astrocytes collaborate with neurons in spreading the "infectious" aβ and Tau drivers of Alzheimer's disease?
    Dal Prà I; Chiarini A; Gui L; Chakravarthy B; Pacchiana R; Gardenal E; Whitfield JF; Armato U
    Neuroscientist; 2015 Feb; 21(1):9-29. PubMed ID: 24740577
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The amyloid-β₄₂ proxy, amyloid-β(25-35), induces normal human cerebral astrocytes to produce amyloid-β₄₂.
    Dal Prà I; Whitfileld JF; Pacchiana R; Bonafini C; Talacchi A; Chakravarthy B; Armato U; Chiarini A
    J Alzheimers Dis; 2011; 24(2):335-47. PubMed ID: 21258151
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulated expression of interleukin-8, RANTES and chemokine receptors in human astrocytic cells infected with HIV-1.
    Cota M; Kleinschmidt A; Ceccherini-Silberstein F; Aloisi F; Mengozzi M; Mantovani A; Brack-Werner R; Poli G
    J Neurovirol; 2000 Feb; 6(1):75-83. PubMed ID: 10786999
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic increases in intracellular Ca2+, and the release of MCP-1, RANTES, and IL-6 by astrocytes treated with opiates and HIV-1 Tat.
    El-Hage N; Gurwell JA; Singh IN; Knapp PE; Nath A; Hauser KF
    Glia; 2005 Apr; 50(2):91-106. PubMed ID: 15630704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential and cooperative effects of TNFalpha, IL-1beta, and IFNgamma on human conjunctival epithelial cell receptor expression and chemokine release.
    Stahl JL; Cook EB; Graziano FM; Barney NP
    Invest Ophthalmol Vis Sci; 2003 May; 44(5):2010-5. PubMed ID: 12714637
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fibroblast expression of C-C chemokines in response to orthopaedic biomaterial particle challenge in vitro.
    Yaszay B; Trindade MC; Lind M; Goodman SB; Smith RL
    J Orthop Res; 2001 Sep; 19(5):970-6. PubMed ID: 11562149
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.