171 related articles for article (PubMed ID: 32500832)
1. Effects of glutathione and cysteine on pyrrolizidine alkaloid-induced hepatotoxicity and DNA adduct formation in rat primary hepatocytes.
He X; Xia Q; Shi Q; Fu PP
J Environ Sci Health C Toxicol Carcinog; 2020; 38(2):109-123. PubMed ID: 32500832
[TBL] [Abstract][Full Text] [Related]
2. 7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids.
He X; Xia Q; Fu PP
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2017 Apr; 35(2):69-83. PubMed ID: 28418776
[TBL] [Abstract][Full Text] [Related]
3. Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation.
Xia Q; He X; Ma L; Chen S; Fu PP
Chem Res Toxicol; 2018 Jul; 31(7):619-628. PubMed ID: 29855181
[TBL] [Abstract][Full Text] [Related]
4. 7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids.
He X; Xia Q; Ma L; Fu PP
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2016; 34(1):57-76. PubMed ID: 26761716
[TBL] [Abstract][Full Text] [Related]
5. Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.
He X; Xia Q; Wu Q; Tolleson WH; Lin G; Fu PP
Toxicol In Vitro; 2019 Feb; 54():286-294. PubMed ID: 30366057
[TBL] [Abstract][Full Text] [Related]
6. 9-Glutathionyl-6,7-dihydro-1-hydroxymethyl-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats.
Chen M; Li L; Zhong D; Shen S; Zheng J; Chen X
Chem Res Toxicol; 2016 Feb; 29(2):180-9. PubMed ID: 26761523
[TBL] [Abstract][Full Text] [Related]
7. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
Wang YP; Yan J; Fu PP; Chou MW
Toxicol Lett; 2005 Mar; 155(3):411-20. PubMed ID: 15649625
[TBL] [Abstract][Full Text] [Related]
8. 1-Formyl-7-hydroxy-6,7-dihydro-5 H-pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids.
He X; Xia Q; Gamboa da Costa G; Lin G; Fu PP
Chem Res Toxicol; 2019 Jun; 32(6):1193-1203. PubMed ID: 31120748
[TBL] [Abstract][Full Text] [Related]
9. Quantitation of DNA reactive pyrrolic metabolites of senecionine - A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis.
Xia Q; He X; Shi Q; Lin G; Fu PP
J Food Drug Anal; 2020 Jan; 28(1):167-174. PubMed ID: 31883605
[TBL] [Abstract][Full Text] [Related]
10. Reaction of dehydropyrrolizidine alkaloids with valine and hemoglobin.
Zhao Y; Wang S; Xia Q; Gamboa da Costa G; Doerge DR; Cai L; Fu PP
Chem Res Toxicol; 2014 Oct; 27(10):1720-31. PubMed ID: 25211425
[TBL] [Abstract][Full Text] [Related]
11. Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.
Xia Q; Chou MW; Lin G; Fu PP
Chem Res Toxicol; 2004 May; 17(5):702-8. PubMed ID: 15144228
[TBL] [Abstract][Full Text] [Related]
12. 7-N-Acetylcysteine-pyrrole conjugate-A potent DNA reactive metabolite of pyrrolizidine alkaloids.
He X; Ma L; Xia Q; Fu PP
J Food Drug Anal; 2016 Oct; 24(4):682-694. PubMed ID: 28911605
[TBL] [Abstract][Full Text] [Related]
13. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo.
Wang YP; Fu PP; Chou MW
Int J Environ Res Public Health; 2005 Apr; 2(1):74-9. PubMed ID: 16705803
[TBL] [Abstract][Full Text] [Related]
14. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo.
Wang YP; Yan J; Beger RD; Fu PP; Chou MW
Cancer Lett; 2005 Aug; 226(1):27-35. PubMed ID: 16004930
[TBL] [Abstract][Full Text] [Related]
15. Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.
Chou MW; Wang YP; Yan J; Yang YC; Beger RD; Williams LD; Doerge DR; Fu PP
Toxicol Lett; 2003 Dec; 145(3):239-47. PubMed ID: 14580895
[TBL] [Abstract][Full Text] [Related]
16. 7-glutathione pyrrole adduct: a potential DNA reactive metabolite of pyrrolizidine alkaloids.
Xia Q; Ma L; He X; Cai L; Fu PP
Chem Res Toxicol; 2015 Apr; 28(4):615-20. PubMed ID: 25768656
[TBL] [Abstract][Full Text] [Related]
17. Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid.
Chou MW; Jian Y; Williams LD; Xia Q; Churchwell M; Doerge DR; Fu PP
Chem Res Toxicol; 2003 Sep; 16(9):1130-7. PubMed ID: 12971801
[TBL] [Abstract][Full Text] [Related]
18. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine.
Xia Q; Yan J; Chou MW; Fu PP
Toxicol Lett; 2008 May; 178(2):77-82. PubMed ID: 18395999
[TBL] [Abstract][Full Text] [Related]
19. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine.
Xia Q; Chou MW; Edgar JA; Doerge DR; Fu PP
Cancer Lett; 2006 Jan; 231(1):138-45. PubMed ID: 16356839
[TBL] [Abstract][Full Text] [Related]
20. Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
Yan J; Xia Q; Chou MW; Fu PP
Toxicol Ind Health; 2008 Apr; 24(3):181-8. PubMed ID: 18842697
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
