BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 3251033)

  • 1. Competing pathways in drug metabolism. II. An identical, anterior enzymic distribution for 2- and 5-sulfoconjugation and a posterior localization for 5-glucuronidation of gentisamide in the rat liver.
    Morris ME; Yuen V; Pang KS
    J Pharmacokinet Biopharm; 1988 Dec; 16(6):633-56. PubMed ID: 3251033
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hepatic modeling of metabolite kinetics in sequential and parallel pathways: salicylamide and gentisamide metabolism in perfused rat liver.
    Xu X; Pang KS
    J Pharmacokinet Biopharm; 1989 Dec; 17(6):645-71. PubMed ID: 2635738
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Competing pathways in drug metabolism. I. Effect of input concentration on the conjugation of gentisamide in the once-through in situ perfused rat liver preparation.
    Morris ME; Yuen V; Tang BK; Pang KS
    J Pharmacol Exp Ther; 1988 May; 245(2):614-24. PubMed ID: 3367309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once-through vascularly perfused rat intestine-liver preparation.
    Hirayama H; Pang KS
    Drug Metab Dispos; 1990; 18(5):580-7. PubMed ID: 1981705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat.
    Hirayama H; Morgado J; Gasinska I; Pang KS
    Drug Metab Dispos; 1990; 18(5):588-94. PubMed ID: 1981706
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Normal and retrograde perfusion to probe the zonal distribution of sulfation and glucuronidation activities of harmol in the perfused rat liver preparation.
    Pang KS; Koster H; Halsema IC; Scholtens E; Mulder GJ; Stillwell RN
    J Pharmacol Exp Ther; 1983 Mar; 224(3):647-53. PubMed ID: 6827487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequential metabolism of salicylamide exclusively to gentisamide 5-glucuronide and not gentisamide sulfate conjugates in single-pass in situ perfused rat liver.
    Xu X; Tang BK; Pang KS
    J Pharmacol Exp Ther; 1990 Jun; 253(3):965-73. PubMed ID: 2359032
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequestered endoplasmic reticulum space for sequential metabolism of salicylamide. Coupling of hydroxylation and glucuronidation.
    Tirona RG; Pang KS
    Drug Metab Dispos; 1996 Aug; 24(8):821-33. PubMed ID: 8869815
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nonlinear protein binding and enzyme heterogeneity: effects on hepatic drug removal.
    Xu X; Selick P; Pang KS
    J Pharmacokinet Biopharm; 1993 Feb; 21(1):43-74. PubMed ID: 8410683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Competition between two enzymes for substrate removal in liver: modulating effects due to substrate recruitment of hepatocyte activity.
    Morris ME; Pang KS
    J Pharmacokinet Biopharm; 1987 Oct; 15(5):473-96. PubMed ID: 3694493
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alteration of transit time and direction of flow to probe the heterogeneous distribution of conjugating activities for harmol in the perfused rat liver preparation.
    Dawson JR; Weitering JG; Mulder GJ; Stillwell RN; Pang KS
    J Pharmacol Exp Ther; 1985 Sep; 234(3):691-7. PubMed ID: 4032287
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatic conjugation/deconjugation cycling pathways. Computer simulations examining the effect of Michaelis-Menten parameters, enzyme distribution patterns, and a diffusional barrier on metabolite disposition.
    Hansel SB; Morris ME
    J Pharmacokinet Biopharm; 1996 Apr; 24(2):219-43. PubMed ID: 8875348
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An enzyme-distributed system for lidocaine metabolism in the perfused rat liver preparation.
    Pang KS; Terrell JA; Nelson SD; Feuer KF; Clements MJ; Endrenyi L
    J Pharmacokinet Biopharm; 1986 Apr; 14(2):107-30. PubMed ID: 3746635
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of acetaminophen sulfation by 2,6-dichloro-4-nitrophenol in the perfused rat liver preparation. Lack of a compensatory increase of glucuronidation.
    Fayz S; Cherry WF; Dawson JR; Mulder GJ; Pang KS
    Drug Metab Dispos; 1984; 12(3):323-9. PubMed ID: 6145559
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combined hepatic arterial-portal venous and hepatic arterial-hepatic venous perfusions to probe the abundance of drug metabolizing activities: perihepatic venous O-deethylation activity for phenacetin and periportal sulfation activity for acetaminophen in the once-through rat liver preparation.
    Pang KS; Cherry WF; Accaputo J; Schwab AJ; Goresky CA
    J Pharmacol Exp Ther; 1988 Nov; 247(2):690-700. PubMed ID: 3183964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zonal distribution of paracetamol glucuronidation in the isolated perfused rat liver.
    Mitchell MC; Hamilton R; Wacker L; Branch RA
    Xenobiotica; 1989 Apr; 19(4):389-400. PubMed ID: 2501939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetics of sulfation and glucuronidation of harmol in the perfused rat liver preparation. Disappearance of aberrances in glucuronidation kinetics by inhibition of sulfation.
    Koster H; Halsema I; Scholtens E; Pang KS; Mulder GJ
    Biochem Pharmacol; 1982 Oct; 31(19):3023-8. PubMed ID: 7150332
    [TBL] [Abstract][Full Text] [Related]  

  • 18. First-pass metabolism of salicylamide. Studies in the once-through vascularly perfused rat intestine-liver preparation.
    Xu X; Hirayama H; Pang KS
    Drug Metab Dispos; 1989; 17(5):556-63. PubMed ID: 2573500
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extrahepatic sulfation and glucuronidation in the rat in vivo. Determination of the hepatic extraction ratio of harmol and the extrahepatic contribution to harmol conjugation.
    Mulder GJ; Weitering JG; Scholtens E; Dawson JR; Pang KS
    Biochem Pharmacol; 1984 Oct; 33(19):3081-7. PubMed ID: 6487358
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of retrograde flow on measured blood volume, Disse space, intracellular water space and drug extraction in the perfused rat liver: characterization by the multiple indicator dilution technique.
    Xu N; Chow A; Goresky CA; Pang KS
    J Pharmacol Exp Ther; 1990 Sep; 254(3):914-25. PubMed ID: 2395120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.