These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 32521228)

  • 1. Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
    Dick SD; Federico S; Hughes SM; Pye VE; O'Reilly N; Cherepanov P
    Structure; 2020 Aug; 28(8):954-962.e4. PubMed ID: 32521228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly.
    Bruck I; Kaplan DL
    J Biol Chem; 2015 Jan; 290(2):1210-21. PubMed ID: 25471369
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of human CDC7 kinase in complex with its activator DBF4.
    Hughes S; Elustondo F; Di Fonzo A; Leroux FG; Wong AC; Snijders AP; Matthews SJ; Cherepanov P
    Nat Struct Mol Biol; 2012 Nov; 19(11):1101-7. PubMed ID: 23064647
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition.
    Kitamura R; Fukatsu R; Kakusho N; Cho YS; Taniyama C; Yamazaki S; Toh GT; Yanagi K; Arai N; Chang HJ; Masai H
    J Biol Chem; 2011 Jul; 286(26):23031-43. PubMed ID: 21536671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase.
    Greiwe JF; Miller TCR; Locke J; Martino F; Howell S; Schreiber A; Nans A; Diffley JFX; Costa A
    Nat Struct Mol Biol; 2022 Jan; 29(1):10-20. PubMed ID: 34963704
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.
    Ramer MD; Suman ES; Richter H; Stanger K; Spranger M; Bieberstein N; Duncker BP
    J Biol Chem; 2013 May; 288(21):14926-35. PubMed ID: 23549044
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
    Cheng J; Li N; Huo Y; Dang S; Tye BK; Gao N; Zhai Y
    Nat Commun; 2022 Mar; 13(1):1396. PubMed ID: 35296675
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth.
    Bruck I; Kaplan D
    J Biol Chem; 2009 Oct; 284(42):28823-31. PubMed ID: 19692334
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Budding yeast Dbf4 sequences required for Cdc7 kinase activation and identification of a functional relationship between the Dbf4 and Rev1 BRCT domains.
    Harkins V; Gabrielse C; Haste L; Weinreich M
    Genetics; 2009 Dec; 183(4):1269-82. PubMed ID: 19822727
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput Docking and Molecular Dynamics Simulations towards the Identification of Novel Peptidomimetic Inhibitors against CDC7.
    Makhouri FR; Ghasemi JB
    Mol Inform; 2018 Nov; 37(11):e1800022. PubMed ID: 29984527
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase.
    Ogino K; Takeda T; Matsui E; Iiyama H; Taniyama C; Arai K; Masai H
    J Biol Chem; 2001 Aug; 276(33):31376-87. PubMed ID: 11402029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer.
    Saleh A; Noguchi Y; Aramayo R; Ivanova ME; Stevens KM; Montoya A; Sunidhi S; Carranza NL; Skwark MJ; Speck C
    Nat Commun; 2022 May; 13(1):2915. PubMed ID: 35614055
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation.
    Francis LI; Randell JC; Takara TJ; Uchima L; Bell SP
    Genes Dev; 2009 Mar; 23(5):643-54. PubMed ID: 19270162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Localization of Cdc7 Protein Kinase During DNA Replication in
    Rossbach D; Bryan DS; Hesselberth JR; Sclafani R
    G3 (Bethesda); 2017 Nov; 7(11):3757-3774. PubMed ID: 28924058
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach.
    Wu KZ; Wang GN; Fitzgerald J; Quachthithu H; Rainey MD; Cattaneo A; Bachi A; Santocanale C
    Nucleic Acids Res; 2016 Oct; 44(18):8786-8798. PubMed ID: 27407105
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell.
    Shellman YG; Schauer IE; Oshiro G; Dohrmann P; Sclafani RA
    Mol Gen Genet; 1998 Sep; 259(4):429-36. PubMed ID: 9790600
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells.
    Charych DH; Coyne M; Yabannavar A; Narberes J; Chow S; Wallroth M; Shafer C; Walter AO
    J Cell Biochem; 2008 Jun; 104(3):1075-86. PubMed ID: 18286467
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Firing of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction.
    Seoane AI; Morgan DO
    Curr Biol; 2017 Sep; 27(18):2849-2855.e2. PubMed ID: 28918948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4.
    Sheu YJ; Stillman B
    Nature; 2010 Jan; 463(7277):113-7. PubMed ID: 20054399
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication.
    Jiang W; McDonald D; Hope TJ; Hunter T
    EMBO J; 1999 Oct; 18(20):5703-13. PubMed ID: 10523313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.