These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Huang Y; Su R; Sheng Y; Dong L; Dong Z; Xu H; Ni T; Zhang ZS; Zhang T; Li C; Han L; Zhu Z; Lian F; Wei J; Deng Q; Wang Y; Wunderlich M; Gao Z; Pan G; Zhong D; Zhou H; Zhang N; Gan J; Jiang H; Mulloy JC; Qian Z; Chen J; Yang CG Cancer Cell; 2019 Apr; 35(4):677-691.e10. PubMed ID: 30991027 [TBL] [Abstract][Full Text] [Related]
4. m Cui Q; Shi H; Ye P; Li L; Qu Q; Sun G; Sun G; Lu Z; Huang Y; Yang CG; Riggs AD; He C; Shi Y Cell Rep; 2017 Mar; 18(11):2622-2634. PubMed ID: 28297667 [TBL] [Abstract][Full Text] [Related]
5. Structural characteristics of small-molecule inhibitors targeting Gao S; Li X; Zhang M; Zhang N; Wang R; Chang J Future Med Chem; 2021 Sep; 13(17):1475-1489. PubMed ID: 34240624 [TBL] [Abstract][Full Text] [Related]
6. Chemical Inhibitors Targeting the Oncogenic m Huang Y; Xia W; Dong Z; Yang CG Acc Chem Res; 2023 Nov; 56(21):3010-3022. PubMed ID: 37889223 [TBL] [Abstract][Full Text] [Related]
7. R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m Qing Y; Dong L; Gao L; Li C; Li Y; Han L; Prince E; Tan B; Deng X; Wetzel C; Shen C; Gao M; Chen Z; Li W; Zhang B; Braas D; Ten Hoeve J; Sanchez GJ; Chen H; Chan LN; Chen CW; Ann D; Jiang L; Müschen M; Marcucci G; Plas DR; Li Z; Su R; Chen J Mol Cell; 2021 Mar; 81(5):922-939.e9. PubMed ID: 33434505 [TBL] [Abstract][Full Text] [Related]
8. Targeting FTO suppresses hepatocellular carcinoma by inhibiting ERBB3 and TUBB4A expression. Jiang L; Liang R; Luo Q; Chen Z; Song G Biochem Pharmacol; 2024 Aug; 226():116375. PubMed ID: 38906227 [TBL] [Abstract][Full Text] [Related]
9. Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach. Prakash M; Itoh Y; Fujiwara Y; Takahashi Y; Takada Y; Mellini P; Elboray EE; Terao M; Yamashita Y; Yamamoto C; Yamaguchi T; Kotoku M; Kitao Y; Singh R; Roy R; Obika S; Oba M; Wang DO; Suzuki T J Med Chem; 2021 Nov; 64(21):15810-15824. PubMed ID: 34727689 [TBL] [Abstract][Full Text] [Related]
10. Identification of Specific Zhang Y; Li QN; Zhou K; Xu Q; Zhang CY Anal Chem; 2020 Oct; 92(20):13936-13944. PubMed ID: 32972135 [TBL] [Abstract][Full Text] [Related]
11. FTO in cancer: functions, molecular mechanisms, and therapeutic implications. Li Y; Su R; Deng X; Chen Y; Chen J Trends Cancer; 2022 Jul; 8(7):598-614. PubMed ID: 35346615 [TBL] [Abstract][Full Text] [Related]
12. Medicinal chemistry aspects of fat mass and obesity associated protein: structure, function and inhibitors. Ren C; Cao Z; Liu Y; Wang R; Lin C; Wang Z Future Med Chem; 2024 Aug; 16(16):1705-1726. PubMed ID: 39101588 [TBL] [Abstract][Full Text] [Related]
13. A photo-responsive chemical modulation of m Lan L; Sun YJ; Liu L; Cheng L Chem Commun (Camb); 2021 Oct; 57(81):10548-10551. PubMed ID: 34553720 [TBL] [Abstract][Full Text] [Related]
14. RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells. Tsuruta N; Tsuchihashi K; Ohmura H; Yamaguchi K; Ito M; Ariyama H; Kusaba H; Akashi K; Baba E Biochem Biophys Res Commun; 2020 Sep; 530(1):235-239. PubMed ID: 32828292 [TBL] [Abstract][Full Text] [Related]
15. Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase activity. Han X; Wang N; Li J; Wang Y; Wang R; Chang J Chem Biol Interact; 2019 Jan; 297():80-84. PubMed ID: 30393114 [TBL] [Abstract][Full Text] [Related]
16. m Liu J; Ren D; Du Z; Wang H; Zhang H; Jin Y Biochem Biophys Res Commun; 2018 Aug; 502(4):456-464. PubMed ID: 29842885 [TBL] [Abstract][Full Text] [Related]
17. Glutathione-Bioimprinted Nanoparticles Targeting of N6-methyladenosine FTO Demethylase as a Strategy against Leukemic Stem Cells. Cao K; Du Y; Bao X; Han M; Su R; Pang J; Liu S; Shi Z; Yan F; Feng S Small; 2022 Apr; 18(13):e2106558. PubMed ID: 35119204 [TBL] [Abstract][Full Text] [Related]
18. Identification of Natural Compound Radicicol as a Potent FTO Inhibitor. Wang R; Han Z; Liu B; Zhou B; Wang N; Jiang Q; Qiao Y; Song C; Chai J; Chang J Mol Pharm; 2018 Sep; 15(9):4092-4098. PubMed ID: 30063141 [TBL] [Abstract][Full Text] [Related]
19. Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance. Liu Y; Liang G; Xu H; Dong W; Dong Z; Qiu Z; Zhang Z; Li F; Huang Y; Li Y; Wu J; Yin S; Zhang Y; Guo P; Liu J; Xi JJ; Jiang P; Han D; Yang CG; Xu MM Cell Metab; 2021 Jun; 33(6):1221-1233.e11. PubMed ID: 33910046 [TBL] [Abstract][Full Text] [Related]
20. FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner. Huang J; Sun W; Wang Z; Lv C; Zhang T; Zhang D; Dong W; Shao L; He L; Ji X; Zhang P; Zhang H J Exp Clin Cancer Res; 2022 Jan; 41(1):42. PubMed ID: 35090515 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]