BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 32539804)

  • 1. DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system.
    Tuminauskaite D; Norkunaite D; Fiodorovaite M; Tumas S; Songailiene I; Tamulaitiene G; Sinkunas T
    BMC Biol; 2020 Jun; 18(1):65. PubMed ID: 32539804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determining the Specificity of Cascade Binding, Interference, and Primed Adaptation
    Cooper LA; Stringer AM; Wade JT
    mBio; 2018 Apr; 9(2):. PubMed ID: 29666291
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection.
    Rutkauskas M; Sinkunas T; Songailiene I; Tikhomirova MS; Siksnys V; Seidel R
    Cell Rep; 2015 Mar; 10(9):1534-1543. PubMed ID: 25753419
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference.
    Hochstrasser ML; Taylor DW; Bhat P; Guegler CK; Sternberg SH; Nogales E; Doudna JA
    Proc Natl Acad Sci U S A; 2014 May; 111(18):6618-23. PubMed ID: 24748111
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protospacer-Adjacent Motif Specificity during Clostridioides difficile Type I-B CRISPR-Cas Interference and Adaptation.
    Maikova A; Boudry P; Shiriaeva A; Vasileva A; Boutserin A; Medvedeva S; Semenova E; Severinov K; Soutourina O
    mBio; 2021 Aug; 12(4):e0213621. PubMed ID: 34425703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
    Xiao Y; Luo M; Hayes RP; Kim J; Ng S; Ding F; Liao M; Ke A
    Cell; 2017 Jun; 170(1):48-60.e11. PubMed ID: 28666122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reconstitution and biochemical characterization of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems.
    Xiao Y; Ke A
    Methods Enzymol; 2019; 616():27-41. PubMed ID: 30691647
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Single-Molecule Insight Into Target Recognition by CRISPR-Cas Complexes.
    Rutkauskas M; Krivoy A; Szczelkun MD; Rouillon C; Seidel R
    Methods Enzymol; 2017; 582():239-273. PubMed ID: 28062037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus.
    Sinkunas T; Gasiunas G; Waghmare SP; Dickman MJ; Barrangou R; Horvath P; Siksnys V
    EMBO J; 2013 Feb; 32(3):385-94. PubMed ID: 23334296
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.
    Gong B; Shin M; Sun J; Jung CH; Bolt EL; van der Oost J; Kim JS
    Proc Natl Acad Sci U S A; 2014 Nov; 111(46):16359-64. PubMed ID: 25368186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Avoidance of Trinucleotide Corresponding to Consensus Protospacer Adjacent Motif Controls the Efficiency of Prespacer Selection during Primed Adaptation.
    Musharova O; Vyhovskyi D; Medvedeva S; Guzina J; Zhitnyuk Y; Djordjevic M; Severinov K; Savitskaya E
    mBio; 2018 Dec; 9(6):. PubMed ID: 30514784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of Spacer and Protospacer Sequence Requirements in the Vibrio cholerae Type I-E CRISPR/Cas System.
    Bourgeois J; Lazinski DW; Camilli A
    mSphere; 2020 Nov; 5(6):. PubMed ID: 33208517
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.
    Szczelkun MD; Tikhomirova MS; Sinkunas T; Gasiunas G; Karvelis T; Pschera P; Siksnys V; Seidel R
    Proc Natl Acad Sci U S A; 2014 Jul; 111(27):9798-803. PubMed ID: 24912165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS.
    Majsec K; Bolt EL; Ivančić-Baće I
    BMC Microbiol; 2016 Mar; 16():28. PubMed ID: 26956996
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct Subcellular Localization of a Type I CRISPR Complex and the Cas3 Nuclease in Bacteria.
    Govindarajan S; Borges A; Karambelkar S; Bondy-Denomy J
    J Bacteriol; 2022 May; 204(5):e0010522. PubMed ID: 35389256
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.
    Fagerlund RD; Wilkinson ME; Klykov O; Barendregt A; Pearce FG; Kieper SN; Maxwell HWR; Capolupo A; Heck AJR; Krause KL; Bostina M; Scheltema RA; Staals RHJ; Fineran PC
    Proc Natl Acad Sci U S A; 2017 Jun; 114(26):E5122-E5128. PubMed ID: 28611213
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fidelity of prespacer capture and processing is governed by the PAM-mediated interactions of Cas1-2 adaptation complex in CRISPR-Cas type I-E system.
    Yoganand KN; Muralidharan M; Nimkar S; Anand B
    J Biol Chem; 2019 Dec; 294(52):20039-20053. PubMed ID: 31748409
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
    Hayes RP; Xiao Y; Ding F; van Erp PB; Rajashankar K; Bailey S; Wiedenheft B; Ke A
    Nature; 2016 Feb; 530(7591):499-503. PubMed ID: 26863189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.
    Rollins MF; Chowdhury S; Carter J; Golden SM; Wilkinson RA; Bondy-Denomy J; Lander GC; Wiedenheft B
    Proc Natl Acad Sci U S A; 2017 Jun; 114(26):E5113-E5121. PubMed ID: 28438998
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in Sulfolobus islandicus.
    Peng W; Li H; Hallstrøm S; Peng N; Liang YX; She Q
    RNA Biol; 2013 May; 10(5):738-48. PubMed ID: 23392249
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.