BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 32541389)

  • 1. Peripheral tetrahydrobiopterin is involved in the pathogenesis of mechanical hypersensitivity in a rodent postsurgical pain model.
    Arai H; Takahashi R; Sakamoto Y; Kitano T; Mashita O; Hara S; Yoshikawa S; Kawasaki K; Ichinose H
    Pain; 2020 Nov; 161(11):2520-2531. PubMed ID: 32541389
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
    Cai S; Alp NJ; McDonald D; Smith I; Kay J; Canevari L; Heales S; Channon KM
    Cardiovasc Res; 2002 Sep; 55(4):838-49. PubMed ID: 12176133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shear stress-mediated upregulation of GTP cyclohydrolase/tetrahydrobiopterin pathway ameliorates hypertension-related decline in reendothelialization capacity of endothelial progenitor cells.
    Bai YP; Xiao S; Tang YB; Tan Z; Tang H; Ren Z; Zeng H; Yang Z
    J Hypertens; 2017 Apr; 35(4):784-797. PubMed ID: 28033126
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells.
    Hattori Y; Nakanishi N; Akimoto K; Yoshida M; Kasai K
    Arterioscler Thromb Vasc Biol; 2003 Feb; 23(2):176-82. PubMed ID: 12588756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
    Latremoliere A; Latini A; Andrews N; Cronin SJ; Fujita M; Gorska K; Hovius R; Romero C; Chuaiphichai S; Painter M; Miracca G; Babaniyi O; Remor AP; Duong K; Riva P; Barrett LB; Ferreirós N; Naylor A; Penninger JM; Tegeder I; Zhong J; Blagg J; Channon KM; Johnsson K; Costigan M; Woolf CJ
    Neuron; 2015 Jun; 86(6):1393-406. PubMed ID: 26087165
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat.
    Meyer JT; Sparling BA; McCarty WJ; Zhang M; Soto M; Schneider S; Chen H; Roberts J; Tan H; Kornecook T; Andrews PS; Knutson CG
    J Pharmacol Exp Ther; 2019 Nov; 371(2):476-486. PubMed ID: 31110114
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combining Human and Rodent Genetics to Identify New Analgesics.
    Latremoliere A; Costigan M
    Neurosci Bull; 2018 Feb; 34(1):143-155. PubMed ID: 28667479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of GTP cyclohydrolase I gene expression and tetrahydrobiopterin content in cultured sympathetic neurons by leukemia inhibitory factor and ciliary neurotrophic factor.
    Stegenga SL; Hirayama K; Kapatos G
    J Neurochem; 1996 Jun; 66(6):2541-5. PubMed ID: 8632180
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
    Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
    Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tetrahydrobiopterin biosynthesis in C6 glioma cells: induction of GTP cyclohydrolase I gene expression by lipopolysaccharide and cytokine treatment.
    D'Sa C; Hirayama K; West A; Hahn M; Zhu M; Kapatos G
    Brain Res Mol Brain Res; 1996 Sep; 41(1-2):105-10. PubMed ID: 8883940
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP?
    Kalivendi S; Hatakeyama K; Whitsett J; Konorev E; Kalyanaraman B; Vásquez-Vivar J
    Free Radic Biol Med; 2005 Feb; 38(4):481-91. PubMed ID: 15649650
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carboxy-PTIO increases the tetrahydrobiopterin level in mouse brain microvascular endothelial cells.
    Shimizu S; Ishii M; Iwasaki M; Shiota K; Yamamoto T; Kiuchi Y
    Jpn J Pharmacol; 2001 Sep; 87(1):51-60. PubMed ID: 11676198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The tetrahydrobiopterin pathway and pain.
    Naylor AM; Pojasek KR; Hopkins AL; Blagg J
    Curr Opin Investig Drugs; 2010 Jan; 11(1):19-30. PubMed ID: 20047156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analgesia by inhibiting tetrahydrobiopterin synthesis.
    Costigan M; Latremoliere A; Woolf CJ
    Curr Opin Pharmacol; 2012 Feb; 12(1):92-9. PubMed ID: 22178186
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down-regulation of GTP cyclohydrolase I and tetrahydrobiopterin by melatonin.
    Jang YJ; Hong HN; Lee JD; Hwang O
    Neuroreport; 2000 Nov; 11(16):3627-30. PubMed ID: 11095532
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.
    Gross SS; Levi R
    J Biol Chem; 1992 Dec; 267(36):25722-9. PubMed ID: 1281471
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein.
    Xie L; Smith JA; Gross SS
    J Biol Chem; 1998 Aug; 273(33):21091-8. PubMed ID: 9694862
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats.
    Meininger CJ; Cai S; Parker JL; Channon KM; Kelly KA; Becker EJ; Wood MK; Wade LA; Wu G
    FASEB J; 2004 Dec; 18(15):1900-2. PubMed ID: 15467010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of tetrahydrobiopterin synthesis in rat cardiac myocytes: impact on cytokine-induced NO generation.
    Kasai K; Hattori Y; Banba N; Hattori S; Motohashi S; Shimoda S; Nakanishi N; Gross SS
    Am J Physiol; 1997 Aug; 273(2 Pt 2):H665-72. PubMed ID: 9277482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
    Shimizu S; Shiota K; Yamamoto S; Miyasaka Y; Ishii M; Watabe T; Nishida M; Mori Y; Yamamoto T; Kiuchi Y
    Free Radic Biol Med; 2003 May; 34(10):1343-52. PubMed ID: 12726922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.