413 related articles for article (PubMed ID: 32559136)
1. The hERG channel activator, RPR260243, enhances protective
Shi YP; Pang Z; Venkateshappa R; Gunawan M; Kemp J; Truong E; Chang C; Lin E; Shafaattalab S; Faizi S; Rayani K; Tibbits GF; Claydon VE; Claydon TW
Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H251-H261. PubMed ID: 32559136
[TBL] [Abstract][Full Text] [Related]
2. Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel.
Kang J; Chen XL; Wang H; Ji J; Cheng H; Incardona J; Reynolds W; Viviani F; Tabart M; Rampe D
Mol Pharmacol; 2005 Mar; 67(3):827-36. PubMed ID: 15548764
[TBL] [Abstract][Full Text] [Related]
3. Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243.
Kemp JM; Whittaker DG; Venkateshappa R; Pang Z; Johal R; Sergeev V; Tibbits GF; Mirams GR; Claydon TW
J Gen Physiol; 2021 Oct; 153(10):. PubMed ID: 34398210
[TBL] [Abstract][Full Text] [Related]
4. Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/- long QT syndrome variant.
Venkateshappa R; Hunter DV; Muralidharan P; Nagalingam RS; Huen G; Faizi S; Luthra S; Lin E; Cheng YM; Hughes J; Khelifi R; Dhunna DP; Johal R; Sergeev V; Shafaattalab S; Julian LM; Poburko DT; Laksman Z; Tibbits GF; Claydon TW
Cardiovasc Res; 2023 Nov; 119(15):2522-2535. PubMed ID: 37739930
[TBL] [Abstract][Full Text] [Related]
5. Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds.
Hull CM; Genge CE; Hobbs Y; Rayani K; Lin E; Gunawan M; Shafaattalab S; Tibbits GF; Claydon TW
Am J Physiol Regul Integr Comp Physiol; 2019 Dec; 317(6):R921-R931. PubMed ID: 31664867
[TBL] [Abstract][Full Text] [Related]
6. Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity.
Zhou J; Augelli-Szafran CE; Bradley JA; Chen X; Koci BJ; Volberg WA; Sun Z; Cordes JS
Mol Pharmacol; 2005 Sep; 68(3):876-84. PubMed ID: 15976038
[TBL] [Abstract][Full Text] [Related]
7. Selective inhibition of physiological late Na
El-Bizri N; Li CH; Liu GX; Rajamani S; Belardinelli L
Am J Physiol Heart Circ Physiol; 2018 Feb; 314(2):H236-H245. PubMed ID: 28971840
[TBL] [Abstract][Full Text] [Related]
8. Balance Between Rapid Delayed Rectifier K
Hegyi B; Chen-Izu Y; Izu LT; Rajamani S; Belardinelli L; Bers DM; Bányász T
Circ Arrhythm Electrophysiol; 2020 Apr; 13(4):e008130. PubMed ID: 32202931
[TBL] [Abstract][Full Text] [Related]
9. Compound ICA-105574 prevents arrhythmias induced by cardiac delayed repolarization.
Meng J; Shi C; Li L; Du Y; Xu Y
Eur J Pharmacol; 2013 Oct; 718(1-3):87-97. PubMed ID: 24041920
[TBL] [Abstract][Full Text] [Related]
10. Enhanced repolarization capacity: new potential antiarrhythmic strategy based on HERG channel activation.
Szabó G; Farkas V; Grunnet M; Mohácsi A; Nánási PP
Curr Med Chem; 2011; 18(24):3607-21. PubMed ID: 21774764
[TBL] [Abstract][Full Text] [Related]
11. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
Thomas D; Karle CA; Kiehn J
Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.
Perry M; Sachse FB; Sanguinetti MC
Proc Natl Acad Sci U S A; 2007 Aug; 104(34):13827-32. PubMed ID: 17693551
[TBL] [Abstract][Full Text] [Related]
13. Facilitation of
Furutani K; Tsumoto K; Chen IS; Handa K; Yamakawa Y; Sack JT; Kurachi Y
J Gen Physiol; 2019 Feb; 151(2):214-230. PubMed ID: 30674563
[TBL] [Abstract][Full Text] [Related]
14. Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
Park MH; Lee SH; Chu DH; Won KH; Choi BH; Choe H; Jo SH
J Pharmacol Sci; 2013 Sep; 123(1):67-77. PubMed ID: 24005046
[TBL] [Abstract][Full Text] [Related]
15. Cardiac hERG K
Su S; Sun J; Wang Y; Xu Y
Handb Exp Pharmacol; 2021; 267():139-166. PubMed ID: 33829343
[TBL] [Abstract][Full Text] [Related]
16. Acute alteration of cardiac ECG, action potential, I(Kr) and the human ether-a-go-go-related gene (hERG) K+ channel by PCB 126 and PCB 77.
Park MH; Park WS; Jo SH
Toxicol Appl Pharmacol; 2012 Jul; 262(1):60-9. PubMed ID: 22676973
[TBL] [Abstract][Full Text] [Related]
17. Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
Hansen RS; Diness TG; Christ T; Demnitz J; Ravens U; Olesen SP; Grunnet M
Mol Pharmacol; 2006 Jan; 69(1):266-77. PubMed ID: 16219910
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization.
Perry MD; Ng CA; Mangala MM; Ng TYM; Hines AD; Liang W; Xu MJO; Hill AP; Vandenberg JI
Cardiovasc Res; 2020 Jul; 116(8):1434-1445. PubMed ID: 31628797
[TBL] [Abstract][Full Text] [Related]
19. Ginkgo biloba extract and ginkgolide antiarrhythmic potential by targeting hERG and ICa-L channel.
Zhao X; Yao H; Yin HL; Zhu QL; Sun JL; Ma W; Shi YQ; Liang ZG; Li BX
J Pharmacol Sci; 2013; 123(4):318-27. PubMed ID: 24225402
[TBL] [Abstract][Full Text] [Related]
20. Electrophysiological characterization of a small molecule activator on human ether-a-go-go-related gene (hERG) potassium channel.
Dong X; Liu Y; Niu H; Wang G; Dong L; Zou A; Wang K
J Pharmacol Sci; 2019 Jul; 140(3):284-290. PubMed ID: 31481348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]