235 related articles for article (PubMed ID: 32559496)
1. Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.
Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY
Cancer Cell; 2020 Aug; 38(2):263-278.e6. PubMed ID: 32559496
[TBL] [Abstract][Full Text] [Related]
2. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.
Gong X; Yi J; Carmon KS; Crumbley CA; Xiong W; Thomas A; Fan X; Guo S; An Z; Chang JT; Liu QJ
Oncogene; 2015 Sep; 34(36):4692-701. PubMed ID: 25531322
[TBL] [Abstract][Full Text] [Related]
3. RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia.
Sun R; He L; Lee H; Glinka A; Andresen C; Hübschmann D; Jeremias I; Müller-Decker K; Pabst C; Niehrs C
Cell Rep; 2021 Aug; 36(7):109559. PubMed ID: 34407399
[TBL] [Abstract][Full Text] [Related]
4. Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis.
Han XH; Jin YR; Tan L; Kosciuk T; Lee JS; Yoon JK
Mol Cell Biol; 2014 Feb; 34(4):752-64. PubMed ID: 24344199
[TBL] [Abstract][Full Text] [Related]
5. A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia.
Bi L; Zhou B; Li H; He L; Wang C; Wang Z; Zhu L; Chen M; Gao S
BMC Cancer; 2018 Feb; 18(1):182. PubMed ID: 29439669
[TBL] [Abstract][Full Text] [Related]
6. Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates β-Catenin Signaling and Tumorigenesis in Multiple Cancer Types.
Chartier C; Raval J; Axelrod F; Bond C; Cain J; Dee-Hoskins C; Ma S; Fischer MM; Shah J; Wei J; Ji M; Lam A; Stroud M; Yen WC; Yeung P; Cancilla B; O'Young G; Wang M; Kapoun AM; Lewicki J; Hoey T; Gurney A
Cancer Res; 2016 Feb; 76(3):713-23. PubMed ID: 26719531
[TBL] [Abstract][Full Text] [Related]
7. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ
J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization.
Tan B; Shi X; Zhang J; Qin J; Zhang N; Ren H; Qian M; Siwko S; Carmon K; Liu Q; Han H; Du B; Liu M
Cancer Res; 2018 Sep; 78(17):4929-4942. PubMed ID: 29967265
[TBL] [Abstract][Full Text] [Related]
9. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.
Carmon KS; Gong X; Yi J; Thomas A; Liu Q
Proc Natl Acad Sci U S A; 2014 Apr; 111(13):E1221-9. PubMed ID: 24639526
[TBL] [Abstract][Full Text] [Related]
10. RSPO3-LGR4 Regulates Osteogenic Differentiation Of Human Adipose-Derived Stem Cells Via ERK/FGF Signalling.
Zhang M; Zhang P; Liu Y; Lv L; Zhang X; Liu H; Zhou Y
Sci Rep; 2017 Feb; 7():42841. PubMed ID: 28220828
[TBL] [Abstract][Full Text] [Related]
11. MLN0128, a novel mTOR kinase inhibitor, disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells.
Zeng Z; Wang RY; Qiu YH; Mak DH; Coombes K; Yoo SY; Zhang Q; Jessen K; Liu Y; Rommel C; Fruman DA; Kantarjian HM; Kornblau SM; Andreeff M; Konopleva M
Oncotarget; 2016 Aug; 7(34):55083-55097. PubMed ID: 27391151
[TBL] [Abstract][Full Text] [Related]
12. Bortezomib suppresses self-renewal and leukemogenesis of leukemia stem cell by NF-ĸB-dependent inhibition of CDK6 in MLL-rearranged myeloid leukemia.
Zhou B; Qin Y; Zhou J; Ruan J; Xiong F; Dong J; Huang X; Yu Z; Gao S
J Cell Mol Med; 2021 Mar; 25(6):3124-3135. PubMed ID: 33599085
[TBL] [Abstract][Full Text] [Related]
13. R-spondin 2-LGR4 system regulates growth, migration and invasion, epithelial-mesenchymal transition and stem-like properties of tongue squamous cell carcinoma via Wnt/β-catenin signaling.
Zhang L; Song Y; Ling Z; Li Y; Ren X; Yang J; Wang Z; Xia J; Zhang W; Cheng B
EBioMedicine; 2019 Jun; 44():275-288. PubMed ID: 31097406
[TBL] [Abstract][Full Text] [Related]
14. GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis.
Dietrich PA; Yang C; Leung HH; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY
Blood; 2014 Nov; 124(22):3284-94. PubMed ID: 25293777
[TBL] [Abstract][Full Text] [Related]
15. SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism.
Polak A; Bialopiotrowicz E; Krzymieniewska B; Wozniak J; Stojak M; Cybulska M; Kaniuga E; Mikula M; Jablonska E; Gorniak P; Noyszewska-Kania M; Szydlowski M; Piechna K; Piwocka K; Bugajski L; Lech-Maranda E; Barankiewicz J; Kolkowska-Lesniak A; Patkowska E; Glodkowska-Mrowka E; Baran N; Juszczynski P
Cell Death Dis; 2020 Nov; 11(11):956. PubMed ID: 33159047
[TBL] [Abstract][Full Text] [Related]
16. R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
Liu S; Yin Y; Yu R; Li Y; Zhang W
Biochem Biophys Res Commun; 2018 Apr; 499(1):59-65. PubMed ID: 29555474
[TBL] [Abstract][Full Text] [Related]
17. RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Hilkens J; Timmer NC; Boer M; Ikink GJ; Schewe M; Sacchetti A; Koppens MAJ; Song JY; Bakker ERM
Gut; 2017 Jun; 66(6):1095-1105. PubMed ID: 27511199
[TBL] [Abstract][Full Text] [Related]
18. Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.
Sachs K; Sarver AL; Noble-Orcutt KE; LaRue RS; Antony ML; Chang D; Lee Y; Navis CM; Hillesheim AL; Nykaza IR; Ha NA; Hansen CJ; Karadag FK; Bergerson RJ; Verneris MR; Meredith MM; Schomaker ML; Linden MA; Myers CL; Largaespada DA; Sachs Z
Cancer Res; 2020 Feb; 80(3):458-470. PubMed ID: 31784425
[TBL] [Abstract][Full Text] [Related]
19. The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34
Murone M; Radpour R; Attinger A; Chessex AV; Huguenin AL; Schürch CM; Banz Y; Sengupta S; Aguet M; Rigotti S; Bachhav Y; Massière F; Ramachandra M; McAllister A; Riether C
Mol Cancer Ther; 2017 Aug; 16(8):1497-1510. PubMed ID: 28468777
[TBL] [Abstract][Full Text] [Related]
20. Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells.
Liu L; Liu L; Leung LH; Cooney AJ; Chen C; Rosengart TK; Ma Y; Yang J
J Biol Chem; 2015 Apr; 290(17):10599-609. PubMed ID: 25737450
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
