BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 32571924)

  • 1. Lck bound to coreceptor is less active than free Lck.
    Wei Q; Brzostek J; Sankaran S; Casas J; Hew LS; Yap J; Zhao X; Wojciech L; Gascoigne NRJ
    Proc Natl Acad Sci U S A; 2020 Jul; 117(27):15809-15817. PubMed ID: 32571924
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.
    Granum S; Sundvold-Gjerstad V; Gopalakrishnan RP; Berge T; Koll L; Abrahamsen G; Sørlie M; Spurkland A
    Sci Signal; 2014 Dec; 7(355):ra118. PubMed ID: 25492967
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events.
    Patel VP; Moran M; Low TA; Miceli MC
    J Immunol; 2001 Jan; 166(2):754-64. PubMed ID: 11145647
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes.
    Arcaro A; Grégoire C; Bakker TR; Baldi L; Jordan M; Goffin L; Boucheron N; Wurm F; van der Merwe PA; Malissen B; Luescher IF
    J Exp Med; 2001 Nov; 194(10):1485-95. PubMed ID: 11714755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.
    van Oers NS; Killeen N; Weiss A
    J Exp Med; 1996 Mar; 183(3):1053-62. PubMed ID: 8642247
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential contribution of Lck and Fyn protein tyrosine kinases to intraepithelial lymphocyte development.
    Page ST; van Oers NS; Perlmutter RM; Weiss A; Pullen AM
    Eur J Immunol; 1997 Feb; 27(2):554-62. PubMed ID: 9045930
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide:MHC molecules.
    Lee JE; Cossoy MB; Chau LA; Singh B; Madrenas J
    J Immunol; 1997 Jul; 159(1):61-9. PubMed ID: 9200439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CD146 bound to LCK promotes T cell receptor signaling and antitumor immune responses in mice.
    Duan H; Jing L; Jiang X; Ma Y; Wang D; Xiang J; Chen X; Wu Z; Yan H; Jia J; Liu Z; Feng J; Zhu M; Yan X
    J Clin Invest; 2021 Nov; 131(21):. PubMed ID: 34491908
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Coreceptor function of CD4 in response to MHC class I molecule].
    Zvezdova ES; Grinenko TS; Pobezinskaia EL; Pobezinskiĭ LA; Kazanskiĭ DB
    Mol Biol (Mosk); 2008; 42(4):662-72. PubMed ID: 18856067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development.
    Falahati R; Leitenberg D
    J Immunol; 2007 Feb; 178(4):2056-64. PubMed ID: 17277109
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.
    Casas J; Brzostek J; Zarnitsyna VI; Hong JS; Wei Q; Hoerter JA; Fu G; Ampudia J; Zamoyska R; Zhu C; Gascoigne NR
    Nat Commun; 2014 Nov; 5():5624. PubMed ID: 25427562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.
    Van Laethem F; Tikhonova AN; Pobezinsky LA; Tai X; Kimura MY; Le Saout C; Guinter TI; Adams A; Sharrow SO; Bernhardt G; Feigenbaum L; Singer A
    Cell; 2013 Sep; 154(6):1326-41. PubMed ID: 24034254
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions.
    Lee MS; Tuohy PJ; Kim CY; Yost PP; Lichauco K; Parrish HL; Van Doorslaer K; Kuhns MS
    Elife; 2024 Apr; 12():. PubMed ID: 38639990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling.
    He X; Woodford-Thomas TA; Johnson KG; Shah DD; Thomas ML
    Eur J Immunol; 2002 Sep; 32(9):2578-87. PubMed ID: 12207342
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor.
    Norment AM; Forbush KA; Nguyen N; Malissen M; Perlmutter RM
    J Exp Med; 1997 Jan; 185(1):121-30. PubMed ID: 8996248
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.
    Lysechko TL; Ostergaard HL
    J Immunol; 2005 Jun; 174(12):7807-14. PubMed ID: 15944285
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of T cell development by c-Cbl: essential role of Lck.
    Chiang YJ; Hodes RJ
    Int Immunol; 2015 May; 27(5):245-51. PubMed ID: 25477210
    [TBL] [Abstract][Full Text] [Related]  

  • 18. De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.
    Philipsen L; Reddycherla AV; Hartig R; Gumz J; Kästle M; Kritikos A; Poltorak MP; Prokazov Y; Turbin E; Weber A; Zuschratter W; Schraven B; Simeoni L; Müller AJ
    Sci Signal; 2017 Jan; 10(462):. PubMed ID: 28096507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck.
    Morio T; Chatila T; Geha RS
    Int Immunol; 1997 Jan; 9(1):53-64. PubMed ID: 9043947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The protein tyrosine kinase p56lck regulates TCR expression and T cell selection.
    Ericsson PO; Teh HS
    Int Immunol; 1995 Apr; 7(4):617-24. PubMed ID: 7547689
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.