These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 32572095)

  • 41. Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4.
    Paschkowsky S; Hamzé M; Oestereich F; Munter LM
    J Biol Chem; 2016 Oct; 291(42):21903-21912. PubMed ID: 27563067
    [TBL] [Abstract][Full Text] [Related]  

  • 42. PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2.
    Kuan YH; Gruebl T; Soba P; Eggert S; Nesic I; Back S; Kirsch J; Beyreuther K; Kins S
    J Biol Chem; 2006 Dec; 281(52):40114-23. PubMed ID: 17050537
    [TBL] [Abstract][Full Text] [Related]  

  • 43. RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation.
    Xie Z; Dong Y; Maeda U; Xia W; Tanzi RE
    J Biol Chem; 2007 Feb; 282(7):4318-4325. PubMed ID: 17170108
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.
    Li Q; Südhof TC
    J Biol Chem; 2004 Mar; 279(11):10542-50. PubMed ID: 14699153
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein.
    Cordy JM; Hussain I; Dingwall C; Hooper NM; Turner AJ
    Proc Natl Acad Sci U S A; 2003 Sep; 100(20):11735-40. PubMed ID: 14504402
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase.
    Jung CG; Uhm KO; Horike H; Kim MJ; Misumi S; Ishida A; Ueda Y; Choi EK; Kim YS; Michikawa M; Hida H
    J Alzheimers Dis; 2015; 43(4):1215-28. PubMed ID: 25147119
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Sequences from the low density lipoprotein receptor-related protein (LRP) cytoplasmic domain enhance amyloid beta protein production via the beta-secretase pathway without altering amyloid precursor protein/LRP nuclear signaling.
    Yoon IS; Pietrzik CU; Kang DE; Koo EH
    J Biol Chem; 2005 May; 280(20):20140-7. PubMed ID: 15772078
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
    Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
    Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Structural Modeling of γ-Secretase Aβ
    Hitzenberger M; Zacharias M
    ACS Chem Neurosci; 2019 Mar; 10(3):1826-1840. PubMed ID: 30638370
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The APP family of proteins: similarities and differences.
    Walsh DM; Minogue AM; Sala Frigerio C; Fadeeva JV; Wasco W; Selkoe DJ
    Biochem Soc Trans; 2007 Apr; 35(Pt 2):416-20. PubMed ID: 17371289
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking.
    Paumier JM; Py NA; García-González L; Bernard A; Stephan D; Louis L; Checler F; Khrestchatisky M; Baranger K; Rivera S
    FASEB J; 2019 Feb; 33(2):2910-2927. PubMed ID: 30332299
    [TBL] [Abstract][Full Text] [Related]  

  • 52. GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.
    Munter LM; Voigt P; Harmeier A; Kaden D; Gottschalk KE; Weise C; Pipkorn R; Schaefer M; Langosch D; Multhaup G
    EMBO J; 2007 Mar; 26(6):1702-12. PubMed ID: 17332749
    [TBL] [Abstract][Full Text] [Related]  

  • 53. gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.
    Walsh DM; Fadeeva JV; LaVoie MJ; Paliga K; Eggert S; Kimberly WT; Wasco W; Selkoe DJ
    Biochemistry; 2003 Jun; 42(22):6664-73. PubMed ID: 12779321
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
    Chiocco MJ; Kulnane LS; Younkin L; Younkin S; Evin G; Lamb BT
    J Biol Chem; 2004 Dec; 279(50):52535-42. PubMed ID: 15452128
    [TBL] [Abstract][Full Text] [Related]  

  • 55. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
    von Einem B; Wahler A; Schips T; Serrano-Pozo A; Proepper C; Boeckers TM; Rueck A; Wirth T; Hyman BT; Danzer KM; Thal DR; von Arnim CA
    PLoS One; 2015; 10(6):e0129047. PubMed ID: 26053850
    [TBL] [Abstract][Full Text] [Related]  

  • 56. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
    [TBL] [Abstract][Full Text] [Related]  

  • 57. GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing.
    von Arnim CA; Spoelgen R; Peltan ID; Deng M; Courchesne S; Koker M; Matsui T; Kowa H; Lichtenthaler SF; Irizarry MC; Hyman BT
    J Neurosci; 2006 Sep; 26(39):9913-22. PubMed ID: 17005855
    [TBL] [Abstract][Full Text] [Related]  

  • 58. TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
    Wang J; Lu R; Yang J; Li H; He Z; Jing N; Wang X; Wang Y
    Nat Commun; 2015 Nov; 6():8876. PubMed ID: 26581893
    [TBL] [Abstract][Full Text] [Related]  

  • 59. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Alpha-Linolenic Acid from Perilla frutescens var. japonica Oil Protects Aβ-Induced Cognitive Impairment through Regulation of APP Processing and Aβ Degradation.
    Lee AY; Lee MH; Lee S; Cho EJ
    J Agric Food Chem; 2017 Dec; 65(49):10719-10729. PubMed ID: 29092397
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.