BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 32574056)

  • 1. Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion.
    Salim M; Ramirez G; Peng KY; Clulow AJ; Hawley A; Ramachandruni H; Beilles S; Boyd BJ
    Mol Pharm; 2020 Jul; 17(7):2749-2759. PubMed ID: 32574056
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria.
    Salim M; Khan J; Ramirez G; Murshed M; Clulow AJ; Hawley A; Ramachandruni H; Beilles S; Boyd BJ
    Mol Pharm; 2019 Apr; 16(4):1658-1668. PubMed ID: 30830789
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interactions of Artefenomel (OZ439) with Milk during Digestion: Insights into Digestion-Driven Solubilization and Polymorphic Transformations.
    Salim M; Khan J; Ramirez G; Clulow AJ; Hawley A; Ramachandruni H; Boyd BJ
    Mol Pharm; 2018 Aug; 15(8):3535-3544. PubMed ID: 29932660
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low-Frequency Raman Scattering Spectroscopy as an Accessible Approach to Understand Drug Solubilization in Milk-Based Formulations during Digestion.
    Salim M; Fraser-Miller SJ; Be Rziņš KR; Sutton JJ; Ramirez G; Clulow AJ; Hawley A; Beilles S; Gordon KC; Boyd BJ
    Mol Pharm; 2020 Mar; 17(3):885-899. PubMed ID: 32011151
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy.
    Ristroph KD; Feng J; McManus SA; Zhang Y; Gong K; Ramachandruni H; White CE; Prud'homme RK
    J Transl Med; 2019 Mar; 17(1):97. PubMed ID: 30902103
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial.
    Phyo AP; Jittamala P; Nosten FH; Pukrittayakamee S; Imwong M; White NJ; Duparc S; Macintyre F; Baker M; Möhrle JJ
    Lancet Infect Dis; 2016 Jan; 16(1):61-69. PubMed ID: 26448141
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion.
    Salim M; Fraser-Miller SJ; Sutton JJ; Be Rziņš KR; Hawley A; Clulow AJ; Beilles S; Gordon KC; Boyd BJ
    J Phys Chem Lett; 2019 May; 10(9):2258-2263. PubMed ID: 31013099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
    Charman SA; Arbe-Barnes S; Bathurst IC; Brun R; Campbell M; Charman WN; Chiu FC; Chollet J; Craft JC; Creek DJ; Dong Y; Matile H; Maurer M; Morizzi J; Nguyen T; Papastogiannidis P; Scheurer C; Shackleford DM; Sriraghavan K; Stingelin L; Tang Y; Urwyler H; Wang X; White KL; Wittlin S; Zhou L; Vennerstrom JL
    Proc Natl Acad Sci U S A; 2011 Mar; 108(11):4400-5. PubMed ID: 21300861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439).
    Kim HS; Hammill JT; Guy RK
    J Med Chem; 2017 Apr; 60(7):2651-2653. PubMed ID: 28296396
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Implications of the Digestion of Milk-Based Formulations for the Solubilization of Lopinavir/Ritonavir in a Combination Therapy.
    Salim M; Ramirez G; Clulow AJ; Hawley A; Boyd BJ
    Mol Pharm; 2023 Apr; 20(4):2256-2265. PubMed ID: 36919249
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Revisiting dispersible milk-drug tablets as a solid lipid formulation in the context of digestion.
    Binte Abu Bakar SY; Salim M; Clulow AJ; Hawley A; Boyd BJ
    Int J Pharm; 2019 Jan; 554():179-189. PubMed ID: 30391337
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Curious Case of the OZ439 Mesylate Salt: An Amphiphilic Antimalarial Drug with Diverse Solution and Solid State Structures.
    Clulow AJ; Salim M; Hawley A; Gilbert EP; Boyd BJ
    Mol Pharm; 2018 May; 15(5):2027-2035. PubMed ID: 29558146
    [TBL] [Abstract][Full Text] [Related]  

  • 13. First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials.
    Moehrle JJ; Duparc S; Siethoff C; van Giersbergen PL; Craft JC; Arbe-Barnes S; Charman SA; Gutierrez M; Wittlin S; Vennerstrom JL
    Br J Clin Pharmacol; 2013 Feb; 75(2):524-37. PubMed ID: 22759078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative Lipidomics Analysis of Human Milk and Infant Formulas Using UHPLC-Q-TOF-MS.
    Zhang X; Liu L; Wang L; Pan Y; Hao X; Zhang G; Li X; Hussain M
    J Agric Food Chem; 2021 Jan; 69(3):1146-1155. PubMed ID: 33464051
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439).
    Dong Y; Wang X; Kamaraj S; Bulbule VJ; Chiu FC; Chollet J; Dhanasekaran M; Hein CD; Papastogiannidis P; Morizzi J; Shackleford DM; Barker H; Ryan E; Scheurer C; Tang Y; Zhao Q; Zhou L; White KL; Urwyler H; Charman WN; Matile H; Wittlin S; Charman SA; Vennerstrom JL
    J Med Chem; 2017 Apr; 60(7):2654-2668. PubMed ID: 28052200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Triacylglycerol Containing Medium-Chain Fatty Acids: Comparison of Human Milk and Infant Formulas on Lipolysis during
    Yuan T; Geng Z; Dai X; Zhang X; Wei W; Wang X; Jin Q
    J Agric Food Chem; 2020 Apr; 68(14):4187-4195. PubMed ID: 32186380
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers.
    McCarthy JS; Baker M; O'Rourke P; Marquart L; Griffin P; Hooft van Huijsduijnen R; Möhrle JJ
    J Antimicrob Chemother; 2016 Sep; 71(9):2620-7. PubMed ID: 27272721
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
    Alskär LC; Parrow A; Keemink J; Johansson P; Abrahamsson B; Bergström CAS
    J Control Release; 2019 Jun; 304():90-100. PubMed ID: 31047962
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential Effects of TPM, A Phosphorylated Tocopherol Mixture, and Other Tocopherol Derivatives as Excipients for Enhancing the Solubilization of Co-Enzyme Q10 as a Lipophilic Drug During Digestion of Lipid- Based Formulations.
    Pham A; Gavin PD; Libinaki R; Ramirez G; Khan JT; Boyd BJ
    Curr Drug Deliv; 2019; 16(7):628-636. PubMed ID: 31385769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action.
    Dubar F; Khalife J; Brocard J; Dive D; Biot C
    Molecules; 2008 Nov; 13(11):2900-7. PubMed ID: 19020475
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.