These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 32580085)

  • 1. Ubiquitin-mediated regulation of sterol homeostasis.
    van den Boomen DJH; Volkmar N; Lehner PJ
    Curr Opin Cell Biol; 2020 Aug; 65():103-111. PubMed ID: 32580085
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.
    Jiang LY; Jiang W; Tian N; Xiong YN; Liu J; Wei J; Wu KY; Luo J; Shi XJ; Song BL
    J Biol Chem; 2018 Mar; 293(11):4047-4055. PubMed ID: 29374057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.
    Menzies SA; Volkmar N; van den Boomen DJ; Timms RT; Dickson AS; Nathan JA; Lehner PJ
    Elife; 2018 Dec; 7():. PubMed ID: 30543180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
    Song BL; Sever N; DeBose-Boyd RA
    Mol Cell; 2005 Sep; 19(6):829-40. PubMed ID: 16168377
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis.
    Tan JME; Cook ECL; van den Berg M; Scheij S; Zelcer N; Loregger A
    Atherosclerosis; 2019 Feb; 281():137-142. PubMed ID: 30658189
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
    Tsai YC; Leichner GS; Pearce MM; Wilson GL; Wojcikiewicz RJ; Roitelman J; Weissman AM
    Mol Biol Cell; 2012 Dec; 23(23):4484-94. PubMed ID: 23087214
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Jo Y; Sguigna PV; DeBose-Boyd RA
    J Biol Chem; 2011 Apr; 286(17):15022-31. PubMed ID: 21343306
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
    Lee JN; Song B; DeBose-Boyd RA; Ye J
    J Biol Chem; 2006 Dec; 281(51):39308-15. PubMed ID: 17043353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase.
    Faulkner RA; Yang Y; Tsien J; Qin T; DeBose-Boyd RA
    Proc Natl Acad Sci U S A; 2024 Feb; 121(7):e2318822121. PubMed ID: 38319967
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.
    Song BL; DeBose-Boyd RA
    J Biol Chem; 2004 Jul; 279(27):28798-806. PubMed ID: 15090540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase.
    Cao J; Wang J; Qi W; Miao HH; Wang J; Ge L; DeBose-Boyd RA; Tang JJ; Li BL; Song BL
    Cell Metab; 2007 Aug; 6(2):115-28. PubMed ID: 17681147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase.
    Johnson BM; DeBose-Boyd RA
    Semin Cell Dev Biol; 2018 Sep; 81():121-128. PubMed ID: 29107682
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-SREBP2 Provides a Mechanism for Dynamic Control of Cellular Cholesterol Homeostasis.
    Ozkan-Nikitaras T; Grzesik DJ; Romano LEL; Chapple JP; King PJ; Shoulders CC
    Cells; 2024 Jul; 13(15):. PubMed ID: 39120286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol.
    Schumacher MM; DeBose-Boyd RA
    Annu Rev Biochem; 2021 Jun; 90():659-679. PubMed ID: 34153214
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The UPS and downs of cholesterol homeostasis.
    Sharpe LJ; Cook EC; Zelcer N; Brown AJ
    Trends Biochem Sci; 2014 Nov; 39(11):527-35. PubMed ID: 25220377
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver.
    Hwang S; Hartman IZ; Calhoun LN; Garland K; Young GA; Mitsche MA; McDonald J; Xu F; Engelking L; DeBose-Boyd RA
    J Biol Chem; 2016 Jun; 291(26):13479-94. PubMed ID: 27129778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase.
    Jo Y; Debose-Boyd RA
    Crit Rev Biochem Mol Biol; 2010 Jun; 45(3):185-98. PubMed ID: 20482385
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.
    Gardner RG; Shearer AG; Hampton RY
    Mol Cell Biol; 2001 Jul; 21(13):4276-91. PubMed ID: 11390656
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.
    Miao H; Jiang W; Ge L; Li B; Song B
    Acta Biochim Biophys Sin (Shanghai); 2010 May; 42(5):303-10. PubMed ID: 20458442
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.
    Jo Y; Lee PC; Sguigna PV; DeBose-Boyd RA
    Proc Natl Acad Sci U S A; 2011 Dec; 108(51):20503-8. PubMed ID: 22143767
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.