These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 3258773)

  • 1. Modulation of nitrosourea resistance in myeloid leukemias.
    Gerson SL; Trey JE
    Blood; 1988 May; 71(5):1487-94. PubMed ID: 3258773
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potentiation of nitrosourea cytotoxicity in human leukemic cells by inactivation of O6-alkylguanine-DNA alkyltransferase.
    Gerson SL; Trey JE; Miller K
    Cancer Res; 1988 Mar; 48(6):1521-7. PubMed ID: 3162197
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU.
    Gerson SL; Phillips W; Kastan M; Dumenco LL; Donovan C
    Blood; 1996 Sep; 88(5):1649-55. PubMed ID: 8781420
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine.
    Gerson SL; Berger NA; Arce C; Petzold SJ; Willson JK
    Biochem Pharmacol; 1992 Mar; 43(5):1101-7. PubMed ID: 1554383
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells.
    Allay JA; Dumenco LL; Koc ON; Liu L; Gerson SL
    Blood; 1995 Jun; 85(11):3342-51. PubMed ID: 7756667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of human lymphocyte O6-alkylguanine-DNA alkyltransferase by streptozotocin in vivo.
    Gerson SL
    Cancer Res; 1989 Jun; 49(11):3134-8. PubMed ID: 2524250
    [TBL] [Abstract][Full Text] [Related]  

  • 7. O6-alkylguanine-DNA alkyltransferase. A target for the modulation of drug resistance.
    Gerson SL; Willson JK
    Hematol Oncol Clin North Am; 1995 Apr; 9(2):431-50. PubMed ID: 7642472
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synergistic efficacy of O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone.
    Gerson SL; Zborowska E; Norton K; Gordon NH; Willson JK
    Biochem Pharmacol; 1993 Jan; 45(2):483-91. PubMed ID: 8435098
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Repair of O6-alkylguanine during DNA synthesis in murine bone marrow hematopoietic precursors.
    Gerson SL; Trey JE; Miller K; Benjamin E
    Cancer Res; 1987 Jan; 47(1):89-95. PubMed ID: 3539320
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased killing of prostate, breast, colon, and lung tumor cells by the combination of inactivators of O6-alkylguanine-DNA alkyltransferase and N,N'-bis(2-chloroethyl)-N-nitrosourea.
    Pegg AE; Swenn K; Chae MY; Dolan ME; Moschel RC
    Biochem Pharmacol; 1995 Oct; 50(8):1141-8. PubMed ID: 7488227
    [TBL] [Abstract][Full Text] [Related]  

  • 11. O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
    Phillips WP; Willson JK; Markowitz SD; Zborowska E; Zaidi NH; Liu L; Gordon NH; Gerson SL
    Cancer Res; 1997 Nov; 57(21):4817-23. PubMed ID: 9354444
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N'-bis (2-chloroethyl)-N-nitrosourea.
    Loktionova NA; Pegg AE
    Cancer Res; 1996 Apr; 56(7):1578-83. PubMed ID: 8603405
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Davis BM; Reese JS; Koç ON; Lee K; Schupp JE; Gerson SL
    Cancer Res; 1997 Nov; 57(22):5093-9. PubMed ID: 9371508
    [TBL] [Abstract][Full Text] [Related]  

  • 14. O6-alkylguanine DNA-alkyltransferase is not a major determinant of sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea in four medulloblastoma cell lines.
    Silber JR; Bobola MS; Ewers TG; Muramoto M; Berger MS
    Oncol Res; 1992; 4(6):241-8. PubMed ID: 1421617
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of O6-alkylguanine DNA alkyltransferase in limiting nitrosourea-induced sister chromatid exchanges in proliferating human lymphocytes.
    Trey JE; Gerson SL
    Cancer Res; 1989 Apr; 49(8):1899-903. PubMed ID: 2702633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
    Liu L; Markowitz S; Gerson SL
    Cancer Res; 1996 Dec; 56(23):5375-9. PubMed ID: 8968088
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of O6-alkylguanine-DNA alkyltransferase in rats following intravenous administration of O6-methylguanine.
    Dexter EU; Yamashita TS; Donovan C; Gerson SL
    Cancer Res; 1989 Jul; 49(13):3520-4. PubMed ID: 2731174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer.
    Gerson SL; Berger SJ; Varnes ME; Donovan C
    Biochem Pharmacol; 1994 Aug; 48(3):543-8. PubMed ID: 8068041
    [TBL] [Abstract][Full Text] [Related]  

  • 19. O6-Benzylguanine potentiates BCNU but not busulfan toxicity in hematopoietic stem cells.
    Westerhof GR; Down JD; Blokland I; Wood M; Boudewijn A; Watson AJ; McGown AT; Ploemacher RE; Margison GP
    Exp Hematol; 2001 May; 29(5):633-8. PubMed ID: 11376877
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regeneration of O6-alkylguanine-DNA alkyltransferase in human lymphocytes after nitrosourea exposure.
    Gerson SL
    Cancer Res; 1988 Sep; 48(18):5368-73. PubMed ID: 3409258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.