These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 32591930)

  • 21. Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency.
    Szabó A; Oláh J; Szunyogh S; Lehotzky A; Szénási T; Csaplár M; Schiedel M; Lőw P; Jung M; Ovádi J
    Sci Rep; 2017 Dec; 7(1):17070. PubMed ID: 29213065
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Recent advances in inhibitors of sirtuin1/2: an update and perspective.
    Zhou Z; Ma T; Zhu Q; Xu Y; Zha X
    Future Med Chem; 2018 Apr; 10(8):907-934. PubMed ID: 29642711
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide.
    Smith BC; Denu JM
    Biochemistry; 2007 Dec; 46(50):14478-86. PubMed ID: 18027980
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.
    Farooqi AS; Hong JY; Cao J; Lu X; Price IR; Zhao Q; Kosciuk T; Yang M; Bai JJ; Lin H
    J Med Chem; 2019 Apr; 62(8):4131-4141. PubMed ID: 30986062
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2.
    Huhtiniemi T; Salo HS; Suuronen T; Poso A; Salminen A; Leppänen J; Jarho E; Lahtela-Kakkonen M
    J Med Chem; 2011 Oct; 54(19):6456-68. PubMed ID: 21895016
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels.
    Skoge RH; Dölle C; Ziegler M
    DNA Repair (Amst); 2014 Nov; 23():33-8. PubMed ID: 24814981
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors.
    Khanfar MA; Quinti L; Wang H; Choi SH; Kazantsev AG; Silverman RB
    Eur J Med Chem; 2014 Apr; 76():414-26. PubMed ID: 24602787
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition.
    Kaya SG; Eren G; Massarotti A; Bakar-Ates F; Ozkan E; Gozelle M; Ozkan Y
    Drug Dev Res; 2024 Jun; 85(4):e22224. PubMed ID: 38867474
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
    Sinatra L; Vogelmann A; Friedrich F; Tararina MA; Neuwirt E; Colcerasa A; König P; Toy L; Yesiloglu TZ; Hilscher S; Gaitzsch L; Papenkordt N; Zhai S; Zhang L; Romier C; Einsle O; Sippl W; Schutkowski M; Gross O; Bendas G; Christianson DW; Hansen FK; Jung M; Schiedel M
    J Med Chem; 2023 Nov; 66(21):14787-14814. PubMed ID: 37902787
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation.
    Siegel D; Bersie S; Harris P; Di Francesco A; Armstrong M; Reisdorph N; Bernier M; de Cabo R; Fritz K; Ross D
    Redox Biol; 2021 Feb; 39():101840. PubMed ID: 33360352
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin.
    Li W; Zhang B; Tang J; Cao Q; Wu Y; Wu C; Guo J; Ling EA; Liang F
    J Neurosci; 2007 Mar; 27(10):2606-16. PubMed ID: 17344398
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
    North BJ; Marshall BL; Borra MT; Denu JM; Verdin E
    Mol Cell; 2003 Feb; 11(2):437-44. PubMed ID: 12620231
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach.
    Cui H; Kamal Z; Ai T; Xu Y; More SS; Wilson DJ; Chen L
    J Med Chem; 2014 Oct; 57(20):8340-57. PubMed ID: 25275824
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer's-Disease Related Pathology.
    Silva DF; Esteves AR; Oliveira CR; Cardoso SM
    Mol Neurobiol; 2017 Aug; 54(6):4021-4040. PubMed ID: 27311773
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Propofol inhibits SIRT2 deacetylase through a conformation-specific, allosteric site.
    Weiser BP; Eckenhoff RG
    J Biol Chem; 2015 Mar; 290(13):8559-68. PubMed ID: 25666612
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Emerging Role of Sirtuin 2 in Parkinson's Disease.
    Liu Y; Zhang Y; Zhu K; Chi S; Wang C; Xie A
    Front Aging Neurosci; 2019; 11():372. PubMed ID: 31998119
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson's Disease.
    Esteves AR; Arduíno DM; Silva DF; Viana SD; Pereira FC; Cardoso SM
    Mol Neurobiol; 2018 Feb; 55(2):1440-1462. PubMed ID: 28168426
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Chroman-4-one- and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells.
    Seifert T; Malo M; Kokkola T; Engen K; Fridén-Saxin M; Wallén EA; Lahtela-Kakkonen M; Jarho EM; Luthman K
    J Med Chem; 2014 Dec; 57(23):9870-88. PubMed ID: 25383691
    [TBL] [Abstract][Full Text] [Related]  

  • 39. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6.
    Skoge RH; Ziegler M
    J Cell Sci; 2016 Aug; 129(15):2972-82. PubMed ID: 27311481
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects.
    Choi G; Lee J; Ji JY; Woo J; Kang NS; Cho SY; Kim HR; Ha JD; Han SY
    Int J Oncol; 2013 Oct; 43(4):1205-11. PubMed ID: 23900402
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.