327 related articles for article (PubMed ID: 32597830)
1. Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease.
Sarkar S; Nguyen HM; Malovic E; Luo J; Langley M; Palanisamy BN; Singh N; Manne S; Neal M; Gabrielle M; Abdalla A; Anantharam P; Rokad D; Panicker N; Singh V; Ay M; Charli A; Harischandra D; Jin LW; Jin H; Rangaraju S; Anantharam V; Wulff H; Kanthasamy AG
J Clin Invest; 2020 Aug; 130(8):4195-4212. PubMed ID: 32597830
[TBL] [Abstract][Full Text] [Related]
2. Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.
Panicker N; Saminathan H; Jin H; Neal M; Harischandra DS; Gordon R; Kanthasamy K; Lawana V; Sarkar S; Luo J; Anantharam V; Kanthasamy AG; Kanthasamy A
J Neurosci; 2015 Jul; 35(27):10058-77. PubMed ID: 26157004
[TBL] [Abstract][Full Text] [Related]
3. The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo.
Di Lucente J; Nguyen HM; Wulff H; Jin LW; Maezawa I
Glia; 2018 Sep; 66(9):1881-1895. PubMed ID: 30043400
[TBL] [Abstract][Full Text] [Related]
4. Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.
Gordon R; Singh N; Lawana V; Ghosh A; Harischandra DS; Jin H; Hogan C; Sarkar S; Rokad D; Panicker N; Anantharam V; Kanthasamy AG; Kanthasamy A
Neurobiol Dis; 2016 Sep; 93():96-114. PubMed ID: 27151770
[TBL] [Abstract][Full Text] [Related]
5. Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.
Panicker N; Sarkar S; Harischandra DS; Neal M; Kam TI; Jin H; Saminathan H; Langley M; Charli A; Samidurai M; Rokad D; Ghaisas S; Pletnikova O; Dawson VL; Dawson TM; Anantharam V; Kanthasamy AG; Kanthasamy A
J Exp Med; 2019 Jun; 216(6):1411-1430. PubMed ID: 31036561
[TBL] [Abstract][Full Text] [Related]
6. Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells.
Sarkar S; Dammer EB; Malovic E; Olsen AL; Raza SA; Gao T; Xiao H; Oliver DL; Duong D; Joers V; Seyfried N; Huang M; Kukar T; Tansey MG; Kanthasamy AG; Rangaraju S
Front Immunol; 2020; 11():33. PubMed ID: 32082315
[TBL] [Abstract][Full Text] [Related]
7. Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
Zhang X; Liang P; Zhang Y; Wu Y; Song Y; Wang X; Chen T; Peng B; Liu W; Yin J; Han S; He X
Int J Mol Sci; 2022 Nov; 23(23):. PubMed ID: 36499018
[TBL] [Abstract][Full Text] [Related]
8. Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept.
Maezawa I; Nguyen HM; Di Lucente J; Jenkins DP; Singh V; Hilt S; Kim K; Rangaraju S; Levey AI; Wulff H; Jin LW
Brain; 2018 Feb; 141(2):596-612. PubMed ID: 29272333
[TBL] [Abstract][Full Text] [Related]
9. HIV-1 Tat protein increases microglial outward K(+) current and resultant neurotoxic activity.
Liu J; Xu P; Collins C; Liu H; Zhang J; Keblesh JP; Xiong H
PLoS One; 2013; 8(5):e64904. PubMed ID: 23738010
[TBL] [Abstract][Full Text] [Related]
10. CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson's disease.
Li Y; Niu M; Zhao A; Kang W; Chen Z; Luo N; Zhou L; Zhu X; Lu L; Liu J
J Neuroinflammation; 2019 Dec; 16(1):263. PubMed ID: 31831012
[TBL] [Abstract][Full Text] [Related]
11. miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease.
Zhang J; Dongwei Zhou ; Zhang Z; Xinhui Qu ; Kunwang Bao ; Guohui Lu ; Jian Duan
Biochem Biophys Res Commun; 2019 Nov; 519(4):740-746. PubMed ID: 31547989
[TBL] [Abstract][Full Text] [Related]
12. Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease.
Williams GP; Schonhoff AM; Jurkuvenaite A; Thome AD; Standaert DG; Harms AS
J Neuroinflammation; 2018 Aug; 15(1):244. PubMed ID: 30165873
[TBL] [Abstract][Full Text] [Related]
13. Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease.
Ramesha S; Rayaprolu S; Bowen CA; Giver CR; Bitarafan S; Nguyen HM; Gao T; Chen MJ; Nwabueze N; Dammer EB; Engstrom AK; Xiao H; Pennati A; Seyfried NT; Katz DJ; Galipeau J; Wulff H; Waller EK; Wood LB; Levey AI; Rangaraju S
Proc Natl Acad Sci U S A; 2021 Mar; 118(11):. PubMed ID: 33649184
[TBL] [Abstract][Full Text] [Related]
14. Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.
Reynolds AD; Glanzer JG; Kadiu I; Ricardo-Dukelow M; Chaudhuri A; Ciborowski P; Cerny R; Gelman B; Thomas MP; Mosley RL; Gendelman HE
J Neurochem; 2008 Mar; 104(6):1504-25. PubMed ID: 18036154
[TBL] [Abstract][Full Text] [Related]
15. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation.
Rangaraju S; Raza SA; Pennati A; Deng Q; Dammer EB; Duong D; Pennington MW; Tansey MG; Lah JJ; Betarbet R; Seyfried NT; Levey AI
J Neuroinflammation; 2017 Jun; 14(1):128. PubMed ID: 28651603
[TBL] [Abstract][Full Text] [Related]
16. Extracellular α-synuclein--a possible initiator of inflammation in Parkinson's disease.
Ren WQ; Tian ZM; Yin F; Sun JZ; Zhang JN
Pharmazie; 2016 Feb; 71(2):51-5. PubMed ID: 27004367
[TBL] [Abstract][Full Text] [Related]
17. Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant.
Hoenen C; Gustin A; Birck C; Kirchmeyer M; Beaume N; Felten P; Grandbarbe L; Heuschling P; Heurtaux T
PLoS One; 2016; 11(9):e0162717. PubMed ID: 27622765
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.
Qin H; Buckley JA; Li X; Liu Y; Fox TH; Meares GP; Yu H; Yan Z; Harms AS; Li Y; Standaert DG; Benveniste EN
J Neurosci; 2016 May; 36(18):5144-59. PubMed ID: 27147665
[TBL] [Abstract][Full Text] [Related]
19. Neuroinflammation and protein pathology in Parkinson's disease dementia.
Kouli A; Camacho M; Allinson K; Williams-Gray CH
Acta Neuropathol Commun; 2020 Dec; 8(1):211. PubMed ID: 33272323
[TBL] [Abstract][Full Text] [Related]
20. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease.
Rangaraju S; Gearing M; Jin LW; Levey A
J Alzheimers Dis; 2015; 44(3):797-808. PubMed ID: 25362031
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]