202 related articles for article (PubMed ID: 32598795)
1. [The main results of clinical trials of the efficacy, safety and pharmacokinetics of the perspective anti-tuberculosis drug makozinone (PBTZ169)].
Mariandyshev AO; Khokhlov AL; Smerdin SV; Shcherbakova VS; Igumnova OV; Ozerova IV; Bolgarina AA; Nikitina NA
Ter Arkh; 2020 Apr; 92(3):61-72. PubMed ID: 32598795
[TBL] [Abstract][Full Text] [Related]
2. [Effect of physicochemical properties on the pharmacokinetic parameters of the new representative of benzothiazinones antituberculosis drug macozinonе].
Khokhlov AL; Mariandyshev AO; Shcherbakova VS; Ozerova IV; Kazaishvili YG; Igumnova OV; Bolgarina AA; Rudoy BA
Ter Arkh; 2020 Dec; 92(12):165-171. PubMed ID: 33720590
[TBL] [Abstract][Full Text] [Related]
3. Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169).
Lupien A; Vocat A; Foo CS; Blattes E; Gillon JY; Makarov V; Cole ST
Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30126954
[TBL] [Abstract][Full Text] [Related]
4. Mutations in
Poulton NC; Azadian ZA; DeJesus MA; Rock JM
Antimicrob Agents Chemother; 2022 Sep; 66(9):e0090422. PubMed ID: 35920665
[TBL] [Abstract][Full Text] [Related]
5. Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma.
Spaggiari D; Desfontaine V; Cruchon S; Guinchard S; Vocat A; Blattes E; Pitteloud J; Ciullini L; Bardinet C; Ivanyuk A; Makarov V; Ryabova O; Buclin T; Cole ST; Decosterd LA
PLoS One; 2019; 14(5):e0217139. PubMed ID: 31150423
[TBL] [Abstract][Full Text] [Related]
6. Comparative Analysis of Pharmacodynamics in the C3HeB/FeJ Mouse Tuberculosis Model for DprE1 Inhibitors TBA-7371, PBTZ169, and OPC-167832.
Robertson GT; Ramey ME; Massoudi LM; Carter CL; Zimmerman M; Kaya F; Graham BG; Gruppo V; Hastings C; Woolhiser LK; Scott DWL; Asay BC; Eshun-Wilson F; Maidj E; Podell BK; Vásquez JJ; Lyons MA; Dartois V; Lenaerts AJ
Antimicrob Agents Chemother; 2021 Oct; 65(11):e0058321. PubMed ID: 34370580
[TBL] [Abstract][Full Text] [Related]
7. An insight into the discovery, clinical studies, compositions, and patents of macozinone: A drug targeting the DprE1 enzyme of Mycobacterium tuberculosis.
Imran M; Khan SA; Asdaq SMB; Almehmadi M; Abdulaziz O; Kamal M; Alshammari MK; Alsubaihi LI; Hussain KH; Alharbi AS; Alzahrani AK
J Infect Public Health; 2022 Oct; 15(10):1097-1107. PubMed ID: 36122509
[TBL] [Abstract][Full Text] [Related]
8. Towards a new combination therapy for tuberculosis with next generation benzothiazinones.
Makarov V; Lechartier B; Zhang M; Neres J; van der Sar AM; Raadsen SA; Hartkoorn RC; Ryabova OB; Vocat A; Decosterd LA; Widmer N; Buclin T; Bitter W; Andries K; Pojer F; Dyson PJ; Cole ST
EMBO Mol Med; 2014 Mar; 6(3):372-83. PubMed ID: 24500695
[TBL] [Abstract][Full Text] [Related]
9. [Development of antituberculous drugs: current status and future prospects].
Tomioka H; Namba K
Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921
[TBL] [Abstract][Full Text] [Related]
10. In vitro and in vivo antimicrobial activities of a novel piperazine-containing benzothiazinones candidate TZY-5-84 against Mycobacterium tuberculosis.
Guo S; Fu L; Wang B; Chen X; Zhao J; Liu M; Lu Y
Biomed Pharmacother; 2020 Nov; 131():110777. PubMed ID: 33152936
[TBL] [Abstract][Full Text] [Related]
11. API TB Consensus Guidelines 2006: Management of pulmonary tuberculosis, extra-pulmonary tuberculosis and tuberculosis in special situations.
API Consensus Expert Committee
J Assoc Physicians India; 2006 Mar; 54():219-34. PubMed ID: 16800350
[TBL] [Abstract][Full Text] [Related]
12. Phase I Single Ascending Dose and Food Effect Study in Healthy Adults and Phase I/IIa Multiple Ascending Dose Study in Patients with Pulmonary Tuberculosis to Assess Pharmacokinetics, Bactericidal Activity, Tolerability, and Safety of OPC-167832.
Dawson R; Diacon AH; Narunsky K; De Jager VR; Stinson KW; Zhang X; Liu Y; Hafkin J
Antimicrob Agents Chemother; 2023 Jun; 67(6):e0147722. PubMed ID: 37219453
[TBL] [Abstract][Full Text] [Related]
13. Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine.
Desfontaine V; Guinchard S; Marques S; Vocat A; Moulfi F; Versace F; Huser-Pitteloud J; Ivanyuk A; Bardinet C; Makarov V; Ryabova O; André P; Prod'Hom S; Chtioui H; Buclin T; Cole ST; Decosterd L
J Chromatogr B Analyt Technol Biomed Life Sci; 2023 Jan; 1215():123555. PubMed ID: 36563654
[TBL] [Abstract][Full Text] [Related]
14. The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis.
Makarov V; Neres J; Hartkoorn RC; Ryabova OB; Kazakova E; Šarkan M; Huszár S; Piton J; Kolly GS; Vocat A; Conroy TM; Mikušová K; Cole ST
Antimicrob Agents Chemother; 2015 Aug; 59(8):4446-52. PubMed ID: 25987616
[TBL] [Abstract][Full Text] [Related]
15. Identification of benzothiazinones containing an oxime functional moiety as new anti-tuberculosis agents.
Wang A; Lv K; Tao Z; Gu J; Fu L; Liu M; Wan B; Franzblau SG; Ma C; Ma X; Han B; Wang A; Xu S; Lu Y
Eur J Med Chem; 2019 Nov; 181():111595. PubMed ID: 31408806
[TBL] [Abstract][Full Text] [Related]
16.
Shi J; Lu J; Wen S; Zong Z; Huo F; Luo J; Liang Q; Li Y; Huang H; Pang Y
Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30150479
[TBL] [Abstract][Full Text] [Related]
17. In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis.
González-Martínez NA; Lozano-Garza HG; Castro-Garza J; De Osio-Cortez A; Vargas-Villarreal J; Cavazos-Rocha N; Ocampo-Candiani J; Makarov V; Cole ST; Vera-Cabrera L
PLoS Negl Trop Dis; 2015; 9(10):e0004022. PubMed ID: 26474057
[TBL] [Abstract][Full Text] [Related]
18. Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis.
Foo CS; Lechartier B; Kolly GS; Boy-Röttger S; Neres J; Rybniker J; Lupien A; Sala C; Piton J; Cole ST
Antimicrob Agents Chemother; 2016 Nov; 60(11):6451-6459. PubMed ID: 27527085
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety.
Lv K; Tao Z; Liu Q; Yang L; Wang B; Wu S; Wang A; Huang M; Liu M; Lu Y
Eur J Med Chem; 2018 May; 151():1-8. PubMed ID: 29601990
[TBL] [Abstract][Full Text] [Related]
20. [Study on the pharmacodynamic activity of combinations with the new anti-tuberculosis drug pyrifazimine
Liu HT; Fu L; Wang B; Wang N; Li DS; Ding YM; Yao R; Qi XT; Lu Y
Zhonghua Jie He He Hu Xi Za Zhi; 2022 Jun; 45(6):560-566. PubMed ID: 35658380
[No Abstract] [Full Text] [Related]
[Next] [New Search]
