BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 32601232)

  • 1. Mechanism of β-arrestin recruitment by the μ-opioid G protein-coupled receptor.
    Mafi A; Kim SK; Goddard WA
    Proc Natl Acad Sci U S A; 2020 Jul; 117(28):16346-16355. PubMed ID: 32601232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.
    Pedersen MF; Wróbel TM; Märcher-Rørsted E; Pedersen DS; Møller TC; Gabriele F; Pedersen H; Matosiuk D; Foster SR; Bouvier M; Bräuner-Osborne H
    Neuropharmacology; 2020 Apr; 166():107718. PubMed ID: 31351108
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced morphine analgesia in mice lacking beta-arrestin 2.
    Bohn LM; Lefkowitz RJ; Gainetdinov RR; Peppel K; Caron MG; Lin FT
    Science; 1999 Dec; 286(5449):2495-8. PubMed ID: 10617462
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular recognition of morphine and fentanyl by the human μ-opioid receptor.
    Zhuang Y; Wang Y; He B; He X; Zhou XE; Guo S; Rao Q; Yang J; Liu J; Zhou Q; Wang X; Liu M; Liu W; Jiang X; Yang D; Jiang H; Shen J; Melcher K; Chen H; Jiang Y; Cheng X; Wang MW; Xie X; Xu HE
    Cell; 2022 Nov; 185(23):4361-4375.e19. PubMed ID: 36368306
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational insights into the G-protein-biased activation and inactivation mechanisms of the μ opioid receptor.
    Cheng JX; Cheng T; Li WH; Liu GX; Zhu WL; Tang Y
    Acta Pharmacol Sin; 2018 Jan; 39(1):154-164. PubMed ID: 29188799
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The μ-opioid receptor-mediated G
    Xia J; Li X; Zhu H; Zhou X; Chen J; Li Q; Li S; Chu H; Dong M
    Eur J Pharmacol; 2024 Mar; 966():176333. PubMed ID: 38278466
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and Structural Explorations of G-Protein Biased μ-Opioid Receptor Agonists.
    Li X; Guo Y; Li J; Yu Z; Cheng J; Ren F; Jia H; Zhang Y; Cui S; Zhang T; Shi W
    ChemMedChem; 2022 Dec; 17(24):e202200416. PubMed ID: 36210341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biased Activation Mechanism Induced by GPCR Heterodimerization: Observations from μOR/δOR Dimers.
    Chen X; Yuan Y; Chen Y; Yu J; Wang J; Chen J; Guo Y; Pu X
    J Chem Inf Model; 2022 Nov; 62(22):5581-5600. PubMed ID: 36377848
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain.
    Hahn YK; Paris JJ; Lichtman AH; Hauser KF; Sim-Selley LJ; Selley DE; Knapp PE
    Neurobiol Dis; 2016 Aug; 92(Pt B):124-36. PubMed ID: 26845176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of β-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia.
    Muchhala KH; Jacob JC; Dewey WL; Akbarali HI
    Eur J Pharmacol; 2021 May; 899():174007. PubMed ID: 33705801
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring biased activation characteristics by molecular dynamics simulation and machine learning for the μ-opioid receptor.
    Chen J; Gou Q; Chen X; Song Y; Zhang F; Pu X
    Phys Chem Chem Phys; 2024 Apr; 26(14):10698-10710. PubMed ID: 38512140
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular Dynamics Simulations to Investigate How PZM21 Affects the Conformational State of the μ-Opioid Receptor Upon Activation.
    Zhao Z; Huang T; Li J
    Int J Mol Sci; 2020 Jul; 21(13):. PubMed ID: 32630190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TRV130 partial agonism and capacity to induce anti-nociceptive tolerance revealed through reducing available μ-opioid receptor number.
    Singleton S; Baptista-Hon DT; Edelsten E; McCaughey KS; Camplisson E; Hales TG
    Br J Pharmacol; 2021 Apr; 178(8):1855-1868. PubMed ID: 33555037
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and beta-arrestin 2-dependent pathways.
    Miyatake M; Rubinstein TJ; McLennan GP; Belcheva MM; Coscia CJ
    J Neurochem; 2009 Jul; 110(2):662-74. PubMed ID: 19457093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.
    Groer CE; Tidgewell K; Moyer RA; Harding WW; Rothman RB; Prisinzano TE; Bohn LM
    Mol Pharmacol; 2007 Feb; 71(2):549-57. PubMed ID: 17090705
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Usefulness for the combination of G-protein- and β-arrestin-biased ligands of μ-opioid receptors: Prevention of antinociceptive tolerance.
    Mori T; Kuzumaki N; Arima T; Narita M; Tateishi R; Kondo T; Hamada Y; Kuwata H; Kawata M; Yamazaki M; Sugita K; Matsuzawa A; Baba K; Yamauchi T; Higashiyama K; Nonaka M; Miyano K; Uezono Y; Narita M
    Mol Pain; 2017; 13():1744806917740030. PubMed ID: 29056067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1.
    Narayan A; Hunkele A; Xu J; Bassoni DL; Pasternak GW; Pan YX
    Cell Mol Neurobiol; 2021 Jul; 41(5):1059-1074. PubMed ID: 33033993
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform.
    Vasudevan L; Vandeputte M; Deventer M; Wouters E; Cannaert A; Stove CP
    Biochem Pharmacol; 2020 Jul; 177():113910. PubMed ID: 32179045
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks.
    Civciristov S; Huang C; Liu B; Marquez EA; Gondin AB; Schittenhelm RB; Ellisdon AM; Canals M; Halls ML
    J Biol Chem; 2019 Nov; 294(44):16198-16213. PubMed ID: 31515267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the receptor to its cognate G proteins.
    Melkes B; Hejnova L; Novotny J
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Dec; 389(12):1289-1300. PubMed ID: 27600870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.