These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 32608331)

  • 1. Development of triple mutant T790M/C797S allosteric EGFR inhibitors: a computational approach.
    Karnik KS; Sarkate AP; Lokwani DK; Narula IS; Burra PVLS; Wakte PS
    J Biomol Struct Dyn; 2021 Sep; 39(15):5376-5398. PubMed ID: 32608331
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Patel HM; Ahmad I; Pawara R; Shaikh M; Surana S
    J Biomol Struct Dyn; 2021 Mar; 39(4):1491-1505. PubMed ID: 32102624
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computational identification of new TKI as potential noncovalent reversible EGFR
    Abdelmalek D; Smaoui F; Frikha F; Ben Marzoug R; Msalbi D; Souissi A; Aifa MS
    J Biomol Struct Dyn; 2024 Jun; 42(9):4870-4887. PubMed ID: 37349947
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational and Synthetic approach with Biological Evaluation of Substituted Quinoline derivatives as small molecule L858R/T790M/C797S triple mutant EGFR inhibitors targeting resistance in Non-Small Cell Lung Cancer (NSCLC).
    Karnik KS; Sarkate AP; Tiwari SV; Azad R; Burra PVLS; Wakte PS
    Bioorg Chem; 2021 Feb; 107():104612. PubMed ID: 33476869
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rational Computational Design of Fourth-Generation EGFR Inhibitors to Combat Drug-Resistant Non-Small Cell Lung Cancer.
    Park H; Jung HY; Kim K; Kim M; Hong S
    Int J Mol Sci; 2020 Dec; 21(23):. PubMed ID: 33297461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Free energy perturbation guided Synthesis with Biological Evaluation of Substituted Quinoline derivatives as small molecule L858R/T790M/C797S mutant EGFR inhibitors targeting resistance in Non-Small Cell Lung Cancer (NSCLC).
    Karnik KS; Sarkate AP; Tiwari SV; Azad R; Wakte PS
    Bioorg Chem; 2021 Oct; 115():105226. PubMed ID: 34364055
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular Docking, Pharmacokinetic and Molecular Simulation Analysis of Novel Mono-Carbonyl Curcumin Analogs as L858R/T790M/C797S Mutant EGFR Inhibitors.
    Bhandari SV; Kuthe PV; Patil SM; Nagras OG; Sarkate AP; Chaudhari SY; Surve SV
    Chem Biodivers; 2023 Nov; 20(11):e202301081. PubMed ID: 37793119
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p38α MAP kinase inhibitors to overcome EGFR tertiary C797S point mutation associated with osimertinib in non-small cell lung cancer (NSCLC): emergence of fourth-generation EGFR inhibitor.
    Ahmad I; Shaikh M; Surana S; Ghosh A; Patel H
    J Biomol Struct Dyn; 2022 Apr; 40(7):3046-3059. PubMed ID: 33174519
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In-silico evidences for binding of Glucokinase activators to EGFR C797S to overcome EGFR resistance obstacle with mutant-selective allosteric inhibition.
    Patel H; Pawara R; Surana S
    Comput Biol Chem; 2018 Jun; 74():167-189. PubMed ID: 29627693
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insight into binding mechanisms of EGFR allosteric inhibitors using molecular dynamics simulations and free energy calculations.
    Wan S; Yan R; Jiang Y; Li Z; Zhang J; Wu X
    J Biomol Struct Dyn; 2019 Oct; 37(16):4384-4394. PubMed ID: 30499387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction and molecular dynamics simulation study of Osimertinib (AstraZeneca 9291) anticancer drug with the EGFR kinase domain in native protein and mutated L844V and C797S.
    Assadollahi V; Rashidieh B; Alasvand M; Abdolahi A; Lopez JA
    J Cell Biochem; 2019 Aug; 120(8):13046-13055. PubMed ID: 30916819
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BREED based de novo hybridization approach: generating novel T790M/C797S-EGFR tyrosine kinase inhibitors to overcome the problem of mutation and resistance in non small cell lung cancer (NSCLC).
    Patel HM; Shaikh M; Ahmad I; Lokwani D; Surana SJ
    J Biomol Struct Dyn; 2021 May; 39(8):2838-2856. PubMed ID: 32276580
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC.
    Cristina M; Emiliano L; Leonardo S; Giulia S; Roberta G; Adolfo A; Marta SS; Paola S; Samuele R; Pierluigi S; Massimo M; Giovanna M
    Bioorg Chem; 2022 Dec; 129():106219. PubMed ID: 36308853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based virtual screening and molecular dynamics simulations for detecting novel candidates for allosteric inhibition of EGFRT790M.
    Çoban G
    J Biomol Struct Dyn; 2024; 42(2):571-597. PubMed ID: 37029759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular dynamic simulations based discovery and development of thiazolidin-4-one derivatives as EGFR inhibitors targeting resistance in non-small cell lung cancer (NSCLC).
    Karnik KS; Sarkate AP; Lokwani DK; Tiwari SV; Azad R; Wakte PS
    J Biomol Struct Dyn; 2023 Jul; 41(10):4696-4710. PubMed ID: 35532095
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanism study of EGFR allosteric inhibitors using molecular dynamics simulations and free energy calculations.
    Wu X; Guo Q; Li Q; Wan S; Li Z; Zhang J
    J Biomol Struct Dyn; 2022 Aug; 40(13):5848-5857. PubMed ID: 33459177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
    Jia Y; Yun CH; Park E; Ercan D; Manuia M; Juarez J; Xu C; Rhee K; Chen T; Zhang H; Palakurthi S; Jang J; Lelais G; DiDonato M; Bursulaya B; Michellys PY; Epple R; Marsilje TH; McNeill M; Lu W; Harris J; Bender S; Wong KK; Jänne PA; Eck MJ
    Nature; 2016 Jun; 534(7605):129-32. PubMed ID: 27251290
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficacy of immunotherapy targeting the neoantigen derived from epidermal growth factor receptor T790M/C797S mutation in non-small cell lung cancer.
    Akazawa Y; Saito Y; Yoshikawa T; Saito K; Nosaka K; Shimomura M; Mizuno S; Nakamoto Y; Nakatsura T
    Cancer Sci; 2020 Aug; 111(8):2736-2746. PubMed ID: 32391625
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Audit of Molecular Mechanisms of Primary and Secondary Resistance to Various Generations of Tyrosine Kinase Inhibitors in Known Epidermal Growth Factor Receptor-Mutant Non-small Cell Lung Cancer Patients in a Tertiary Centre.
    Suryavanshi M; Jaipuria J; Mattoo S; Dhandha S; Khatri M
    Clin Oncol (R Coll Radiol); 2022 Nov; 34(11):e451-e462. PubMed ID: 35810049
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Response to Brigatinib Targeted Therapy in Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 19 Deletion, T790M, and cis-C797S Triple Mutations: A Case Report.
    Chen ZW; Lin G; Shih HJ; Wu CE
    Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36614045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.