BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 32612149)

  • 1. Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation.
    Stokes ME; Small JC; Vasciaveo A; Shimada K; Hirschhorn T; Califano A; Stockwell BR
    Sci Rep; 2020 Jul; 10(1):10748. PubMed ID: 32612149
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.
    Longo J; Mullen PJ; Yu R; van Leeuwen JE; Masoomian M; Woon DTS; Wang Y; Chen EX; Hamilton RJ; Sweet JM; van der Kwast TH; Fleshner NE; Penn LZ
    Mol Metab; 2019 Jul; 25():119-130. PubMed ID: 31023626
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis.
    Zhang T; Bai R; Wang Q; Wang K; Li X; Liu K; Ryu J; Wang T; Chang X; Ma W; Bode AM; Xia Q; Song Y; Dong Z
    Cancer Prev Res (Phila); 2019 Dec; 12(12):837-848. PubMed ID: 31554629
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications.
    Dimitroulakos J; Ye LY; Benzaquen M; Moore MJ; Kamel-Reid S; Freedman MH; Yeger H; Penn LZ
    Clin Cancer Res; 2001 Jan; 7(1):158-67. PubMed ID: 11205904
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells.
    Xia Z; Tan MM; Wong WW; Dimitroulakos J; Minden MD; Penn LZ
    Leukemia; 2001 Sep; 15(9):1398-407. PubMed ID: 11516100
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differentiation and apoptosis induction by lovastatin and γ-tocotrienol in HL-60 cells via Ras/ERK/NF-κB and Ras/Akt/NF-κB signaling dependent down-regulation of glyoxalase 1 and HMG-CoA reductase.
    Chen CC; Liu TY; Huang SP; Ho CT; Huang TC
    Cell Signal; 2015 Nov; 27(11):2182-90. PubMed ID: 26208883
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent.
    Wang T; Liu L; Chen X; Shen Y; Lian G; Shah N; Davidoff AM; Yang J; Wang R
    Cell Death Dis; 2018 Feb; 9(2):220. PubMed ID: 29445162
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins.
    Herrero-Martin G; López-Rivas A
    FEBS Lett; 2008 Jul; 582(17):2589-94. PubMed ID: 18582466
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Growth inhibition of neuroblastoma cells by lovastatin and L-ascorbic acid is based on different mechanisms.
    Girgert R; Vogt Y; Becke D; Bruchelt G; Schweizer P
    Cancer Lett; 1999 Apr; 137(2):167-72. PubMed ID: 10374838
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma.
    Longo J; Smirnov P; Li Z; Branchard E; van Leeuwen JE; Licht JD; Haibe-Kains B; Andrews DW; Keats JJ; Pugh TJ; Trudel S; Penn LZ
    Leukemia; 2021 Mar; 35(3):796-808. PubMed ID: 32665698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells.
    Göbel A; Breining D; Rauner M; Hofbauer LC; Rachner TD
    Cell Death Dis; 2019 Jan; 10(2):91. PubMed ID: 30692522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mevalonate prevents lovastatin-induced apoptosis in medulloblastoma cell lines.
    Wang W; Macaulay RJ
    Can J Neurol Sci; 1999 Nov; 26(4):305-10. PubMed ID: 10563217
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer.
    Bhardwaj A; Singh H; Trinidad CM; Albarracin CT; Hunt KK; Bedrosian I
    Breast Cancer Res; 2018 Dec; 20(1):150. PubMed ID: 30537987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lovastatin Differentially Affects Neuronal Cholesterol and Amyloid-β Production in vivo and in vitro.
    Mendoza-Oliva A; Ferrera P; Fragoso-Medina J; Arias C
    CNS Neurosci Ther; 2015 Aug; 21(8):631-41. PubMed ID: 26096465
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells.
    Mantha AJ; McFee KE; Niknejad N; Goss G; Lorimer IA; Dimitroulakos J
    J Cancer Res Clin Oncol; 2003 Nov; 129(11):631-41. PubMed ID: 12942316
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth.
    Moriceau G; Roelofs AJ; Brion R; Redini F; Ebetion FH; Rogers MJ; Heymann D
    Cancer; 2012 Feb; 118(3):750-60. PubMed ID: 21751201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells.
    Sivaprasad U; Abbas T; Dutta A
    Mol Cancer Ther; 2006 Sep; 5(9):2310-6. PubMed ID: 16985065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach.
    Dimitroulakos J; Nohynek D; Backway KL; Hedley DW; Yeger H; Freedman MH; Minden MD; Penn LZ
    Blood; 1999 Feb; 93(4):1308-18. PubMed ID: 9949174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma.
    Zhang S; Wei JS; Li SQ; Badgett TC; Song YK; Agarwal S; Coarfa C; Tolman C; Hurd L; Liao H; He J; Wen X; Liu Z; Thiele CJ; Westermann F; Asgharzadeh S; Seeger RC; Maris JM; Guidry Auvil JM; Smith MA; Kolaczyk ED; Shohet J; Khan J
    Cancer Lett; 2016 Feb; 371(2):214-24. PubMed ID: 26683771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MIAT Is an Upstream Regulator of NMYC and the Disruption of the MIAT/NMYC Axis Induces Cell Death in
    Feriancikova B; Feglarova T; Krskova L; Eckschlager T; Vicha A; Hrabeta J
    Int J Mol Sci; 2021 Mar; 22(7):. PubMed ID: 33806217
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.