BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

367 related articles for article (PubMed ID: 32613609)

  • 1. Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ
    Rong Z; Cheng B; Zhong L; Ye X; Li X; Jia L; Li Y; Shue F; Wang N; Cheng Y; Huang X; Liu CC; Fryer JD; Wang X; Zhang YW; Zheng H
    FASEB J; 2020 Aug; 34(8):10984-10997. PubMed ID: 32613609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant
    Cheng Q; Danao J; Talreja S; Wen P; Yin J; Sun N; Li CM; Chui D; Tran D; Koirala S; Chen H; Foltz IN; Wang S; Sambashivan S
    J Biol Chem; 2018 Aug; 293(32):12620-12633. PubMed ID: 29599291
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
    Ellwanger DC; Wang S; Brioschi S; Shao Z; Green L; Case R; Yoo D; Weishuhn D; Rathanaswami P; Bradley J; Rao S; Cha D; Luan P; Sambashivan S; Gilfillan S; Hasson SA; Foltz IN; van Lookeren Campagne M; Colonna M
    Proc Natl Acad Sci U S A; 2021 Jan; 118(3):. PubMed ID: 33446504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease.
    Claes C; Danhash EP; Hasselmann J; Chadarevian JP; Shabestari SK; England WE; Lim TE; Hidalgo JLS; Spitale RC; Davtyan H; Blurton-Jones M
    Mol Neurodegener; 2021 Jul; 16(1):50. PubMed ID: 34301296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain.
    Korvatska O; Kiianitsa K; Ratushny A; Matsushita M; Beeman N; Chien WM; Satoh JI; Dorschner MO; Keene CD; Bammler TK; Bird TD; Raskind WH
    Front Immunol; 2020; 11():559342. PubMed ID: 33101276
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
    Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV
    J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586
    [No Abstract]   [Full Text] [Related]  

  • 7. Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
    Song WM; Joshita S; Zhou Y; Ulland TK; Gilfillan S; Colonna M
    J Exp Med; 2018 Mar; 215(3):745-760. PubMed ID: 29321225
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
    Wang Y; Ulland TK; Ulrich JD; Song W; Tzaferis JA; Hole JT; Yuan P; Mahan TE; Shi Y; Gilfillan S; Cella M; Grutzendler J; DeMattos RB; Cirrito JR; Holtzman DM; Colonna M
    J Exp Med; 2016 May; 213(5):667-75. PubMed ID: 27091843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2).
    Zhong L; Wang Z; Wang D; Wang Z; Martens YA; Wu L; Xu Y; Wang K; Li J; Huang R; Can D; Xu H; Bu G; Chen XF
    Mol Neurodegener; 2018 Mar; 13(1):15. PubMed ID: 29587871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.
    Zhao Y; Wu X; Li X; Jiang LL; Gui X; Liu Y; Sun Y; Zhu B; Piña-Crespo JC; Zhang M; Zhang N; Chen X; Bu G; An Z; Huang TY; Xu H
    Neuron; 2018 Mar; 97(5):1023-1031.e7. PubMed ID: 29518356
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model.
    Wang S; Mustafa M; Yuede CM; Salazar SV; Kong P; Long H; Ward M; Siddiqui O; Paul R; Gilfillan S; Ibrahim A; Rhinn H; Tassi I; Rosenthal A; Schwabe T; Colonna M
    J Exp Med; 2020 Sep; 217(9):. PubMed ID: 32579671
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway.
    Fang Y; Wang J; Yao L; Li C; Wang J; Liu Y; Tao X; Sun H; Liao H
    J Neuroinflammation; 2018 Jul; 15(1):210. PubMed ID: 30029608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease.
    Wang X; Xie Y; Fan X; Wu X; Wang D; Zhu L
    Alzheimers Res Ther; 2024 Jun; 16(1):121. PubMed ID: 38831312
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
    Popescu AS; Butler CA; Allendorf DH; Piers TM; Mallach A; Roewe J; Reinhardt P; Cinti A; Redaelli L; Boudesco C; Pradier L; Pocock JM; Thornton P; Brown GC
    Glia; 2023 Apr; 71(4):974-990. PubMed ID: 36480007
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.
    Zheng H; Liu CC; Atagi Y; Chen XF; Jia L; Yang L; He W; Zhang X; Kang SS; Rosenberry TL; Fryer JD; Zhang YW; Xu H; Bu G
    Neurobiol Aging; 2016 Jun; 42():132-41. PubMed ID: 27143430
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
    Wang Y; Cella M; Mallinson K; Ulrich JD; Young KL; Robinette ML; Gilfillan S; Krishnan GM; Sudhakar S; Zinselmeyer BH; Holtzman DM; Cirrito JR; Colonna M
    Cell; 2015 Mar; 160(6):1061-71. PubMed ID: 25728668
    [TBL] [Abstract][Full Text] [Related]  

  • 17. iPSC-derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss.
    Penney J; Ralvenius WT; Loon A; Cerit O; Dileep V; Milo B; Pao PC; Woolf H; Tsai LH
    Glia; 2024 Feb; 72(2):452-469. PubMed ID: 37969043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
    Hall-Roberts H; Agarwal D; Obst J; Smith TB; Monzón-Sandoval J; Di Daniel E; Webber C; James WS; Mead E; Davis JB; Cowley SA
    Alzheimers Res Ther; 2020 Nov; 12(1):151. PubMed ID: 33198789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Trem2
    Tran KM; Kawauchi S; Kramár EA; Rezaie N; Liang HY; Sakr JS; Gomez-Arboledas A; Arreola MA; Cunha CD; Phan J; Wang S; Collins S; Walker A; Shi KX; Neumann J; Filimban G; Shi Z; Milinkeviciute G; Javonillo DI; Tran K; Gantuz M; Forner S; Swarup V; Tenner AJ; LaFerla FM; Wood MA; Mortazavi A; MacGregor GR; Green KN
    Mol Neurodegener; 2023 Feb; 18(1):12. PubMed ID: 36803190
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) R47H Variant Causes Distinct Age- and Sex-Dependent Musculoskeletal Alterations in Mice.
    Essex AL; Huot JR; Deosthale P; Wagner A; Figueras J; Davis A; Damrath J; Pin F; Wallace J; Bonetto A; Plotkin LI
    J Bone Miner Res; 2022 Jul; 37(7):1366-1381. PubMed ID: 35575023
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.