These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

493 related articles for article (PubMed ID: 32618513)

  • 1. Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca
    Robinson P; Sparrow AJ; Patel S; Malinowska M; Reilly SN; Zhang YH; Casadei B; Watkins H; Redwood C
    Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H306-H319. PubMed ID: 32618513
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypertrophic cardiomyopathy mutations increase myofilament Ca
    Robinson P; Liu X; Sparrow A; Patel S; Zhang YH; Casadei B; Watkins H; Redwood C
    J Biol Chem; 2018 Jul; 293(27):10487-10499. PubMed ID: 29760186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.
    Memo M; Leung MC; Ward DG; dos Remedios C; Morimoto S; Zhang L; Ravenscroft G; McNamara E; Nowak KJ; Marston SB; Messer AE
    Cardiovasc Res; 2013 Jul; 99(1):65-73. PubMed ID: 23539503
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
    Robinson P; Griffiths PJ; Watkins H; Redwood CS
    Circ Res; 2007 Dec; 101(12):1266-73. PubMed ID: 17932326
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
    Rajan S; Ahmed RP; Jagatheesan G; Petrashevskaya N; Boivin GP; Urboniene D; Arteaga GM; Wolska BM; Solaro RJ; Liggett SB; Wieczorek DF
    Circ Res; 2007 Jul; 101(2):205-14. PubMed ID: 17556658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca
    Sparrow AJ; Watkins H; Daniels MJ; Redwood C; Robinson P
    Am J Physiol Heart Circ Physiol; 2020 Mar; 318(3):H715-H722. PubMed ID: 32083971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.
    Ferrantini C; Coppini R; Pioner JM; Gentile F; Tosi B; Mazzoni L; Scellini B; Piroddi N; Laurino A; Santini L; Spinelli V; Sacconi L; De Tombe P; Moore R; Tardiff J; Mugelli A; Olivotto I; Cerbai E; Tesi C; Poggesi C
    J Am Heart Assoc; 2017 Jul; 6(7):. PubMed ID: 28735292
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins.
    Alves ML; Dias FAL; Gaffin RD; Simon JN; Montminy EM; Biesiadecki BJ; Hinken AC; Warren CM; Utter MS; Davis RT; Sakthivel S; Robbins J; Wieczorek DF; Solaro RJ; Wolska BM
    Circ Cardiovasc Genet; 2014 Apr; 7(2):132-143. PubMed ID: 24585742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype.
    Mirza M; Marston S; Willott R; Ashley C; Mogensen J; McKenna W; Robinson P; Redwood C; Watkins H
    J Biol Chem; 2005 Aug; 280(31):28498-506. PubMed ID: 15923195
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
    Lu QW; Morimoto S; Harada K; Du CK; Takahashi-Yanaga F; Miwa Y; Sasaguri T; Ohtsuki I
    J Mol Cell Cardiol; 2003 Dec; 35(12):1421-7. PubMed ID: 14654368
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations.
    Sparrow AJ; Sievert K; Patel S; Chang YF; Broyles CN; Brook FA; Watkins H; Geeves MA; Redwood CS; Robinson P; Daniels MJ
    Circ Res; 2019 Apr; 124(8):1228-1239. PubMed ID: 30732532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional analysis of a unique troponin c mutation, GLY159ASP, that causes familial dilated cardiomyopathy, studied in explanted heart muscle.
    Dyer EC; Jacques AM; Hoskins AC; Ward DG; Gallon CE; Messer AE; Kaski JP; Burch M; Kentish JC; Marston SB
    Circ Heart Fail; 2009 Sep; 2(5):456-64. PubMed ID: 19808376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rat cardiac troponin T mutation (F72L)-mediated impact on thin filament cooperativity is divergently modulated by α- and β-myosin heavy chain isoforms.
    Chandra V; Gollapudi SK; Chandra M
    Am J Physiol Heart Circ Physiol; 2015 Oct; 309(8):H1260-70. PubMed ID: 26342069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alpha-tropomyosin mutations in inherited cardiomyopathies.
    Redwood C; Robinson P
    J Muscle Res Cell Motil; 2013 Aug; 34(3-4):285-94. PubMed ID: 24005378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models.
    Guinto PJ; Haim TE; Dowell-Martino CC; Sibinga N; Tardiff JC
    Am J Physiol Heart Circ Physiol; 2009 Aug; 297(2):H614-26. PubMed ID: 19502551
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypertrophic cardiomyopathy mutation in cardiac troponin T (R95H) attenuates length-dependent activation in guinea pig cardiac muscle fibers.
    Mickelson AV; Chandra M
    Am J Physiol Heart Circ Physiol; 2017 Dec; 313(6):H1180-H1189. PubMed ID: 28842439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin.
    Sommese RF; Nag S; Sutton S; Miller SM; Spudich JA; Ruppel KM
    PLoS One; 2013; 8(12):e83403. PubMed ID: 24367593
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dilated cardiomyopathy mutation (R174W) in troponin T attenuates the length-mediated increase in cross-bridge recruitment and myofilament Ca
    Reda SM; Chandra M
    Am J Physiol Heart Circ Physiol; 2019 Sep; 317(3):H648-H657. PubMed ID: 31373515
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies.
    Lombardi R; Bell A; Senthil V; Sidhu J; Noseda M; Roberts R; Marian AJ
    Cardiovasc Res; 2008 Jul; 79(1):109-17. PubMed ID: 18349139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
    Sequeira V; Wijnker PJ; Nijenkamp LL; Kuster DW; Najafi A; Witjas-Paalberends ER; Regan JA; Boontje N; Ten Cate FJ; Germans T; Carrier L; Sadayappan S; van Slegtenhorst MA; Zaremba R; Foster DB; Murphy AM; Poggesi C; Dos Remedios C; Stienen GJ; Ho CY; Michels M; van der Velden J
    Circ Res; 2013 May; 112(11):1491-505. PubMed ID: 23508784
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.