These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 32621003)

  • 1. Protein-ligand structure determination with the NMR molecular replacement tool, NMR
    Orts J; Riek R
    J Biomol NMR; 2020 Nov; 74(10-11):633-642. PubMed ID: 32621003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NMR-Based Determination of the 3D Structure of the Ligand-Protein Interaction Site without Protein Resonance Assignment.
    Orts J; Wälti MA; Marsh M; Vera L; Gossert AD; Güntert P; Riek R
    J Am Chem Soc; 2016 Apr; 138(13):4393-400. PubMed ID: 26943491
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unveiling the "Three-Finger Pharmacophore" Required for p53-MDM2 Inhibition by Saturation-Transfer Difference (STD) NMR Initial Growth-Rates Approach.
    Angulo J; Goffin SA; Gandhi D; Searcey M; Howell LA
    Chemistry; 2016 Apr; 22(17):5858-62. PubMed ID: 26864212
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding site identification and structure determination of protein-ligand complexes by NMR a semiautomated approach.
    Ziarek JJ; Peterson FC; Lytle BL; Volkman BF
    Methods Enzymol; 2011; 493():241-75. PubMed ID: 21371594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Auto-FACE: an NMR based binding site mapping program for fast chemical exchange protein-ligand systems.
    Krishnamoorthy J; Yu VC; Mok YK
    PLoS One; 2010 Feb; 5(2):e8943. PubMed ID: 20174626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand-receptor binding affinities from saturation transfer difference (STD) NMR spectroscopy: the binding isotherm of STD initial growth rates.
    Angulo J; Enríquez-Navas PM; Nieto PM
    Chemistry; 2010 Jul; 16(26):7803-12. PubMed ID: 20496354
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NMR screening for lead compounds using tryptophan-mutated proteins.
    Rothweiler U; Czarna A; Weber L; Popowicz GM; Brongel K; Kowalska K; Orth M; Stemmann O; Holak TA
    J Med Chem; 2008 Aug; 51(16):5035-42. PubMed ID: 18680271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Advancing fragment binders to lead-like compounds using ligand and protein-based NMR spectroscopy.
    Maurer T
    Methods Enzymol; 2011; 493():469-85. PubMed ID: 21371602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fast Quantitative Validation of 3D Models of Low-Affinity Protein-Ligand Complexes by STD NMR Spectroscopy.
    Nepravishta R; Ramírez-Cárdenas J; Rocha G; Walpole S; Hicks T; Monaco S; Muñoz-García JC; Angulo J
    J Med Chem; 2024 Jun; 67(12):10025-10034. PubMed ID: 38848103
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined automated NOE assignment and structure calculation with CYANA.
    Güntert P; Buchner L
    J Biomol NMR; 2015 Aug; 62(4):453-71. PubMed ID: 25801209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NMR-based structural characterization of large protein-ligand interactions.
    Pellecchia M; Meininger D; Dong Q; Chang E; Jack R; Sem DS
    J Biomol NMR; 2002 Feb; 22(2):165-73. PubMed ID: 11883777
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Complete relaxation and conformational exchange matrix (CORCEMA) analysis of intermolecular saturation transfer effects in reversibly forming ligand-receptor complexes.
    Jayalakshmi V; Krishna NR
    J Magn Reson; 2002 Mar; 155(1):106-18. PubMed ID: 11945039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NMR-based techniques in the hit identification and optimisation processes.
    Pellecchia M; Becattini B; Crowell KJ; Fattorusso R; Forino M; Fragai M; Jung D; Mustelin T; Tautz L
    Expert Opin Ther Targets; 2004 Dec; 8(6):597-611. PubMed ID: 15584865
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein-ligand docking guided by ligand pharmacophore-mapping experiment by NMR.
    Fukunishi Y; Mizukoshi Y; Takeuchi K; Shimada I; Takahashi H; Nakamura H
    J Mol Graph Model; 2011 Nov; 31():20-7. PubMed ID: 21940186
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Application of NMR screening in drug discovery.
    Fejzo J; Lepre C; Xie X
    Curr Top Med Chem; 2003; 3(1):81-97. PubMed ID: 12570779
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NMR-based methods and strategies for drug discovery.
    Salvatella X; Giralt E
    Chem Soc Rev; 2003 Nov; 32(6):365-72. PubMed ID: 14671791
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR spectroscopy tools for structure-aided drug design.
    Homans SW
    Angew Chem Int Ed Engl; 2004 Jan; 43(3):290-300. PubMed ID: 14705081
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data.
    Mohanty B; Williams ML; Doak BC; Vazirani M; Ilyichova O; Wang G; Bermel W; Simpson JS; Chalmers DK; King GF; Mobli M; Scanlon MJ
    J Biomol NMR; 2016 Nov; 66(3):195-208. PubMed ID: 27778134
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMR in structure-based drug design.
    Carneiro MG; Ab E; Theisgen S; Siegal G
    Essays Biochem; 2017 Nov; 61(5):485-493. PubMed ID: 29118095
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rapid Protein-Ligand Affinity Determination by Photoinduced Hyperpolarized NMR.
    Bütikofer M; Stadler GR; Kadavath H; Cadalbert R; Torres F; Riek R
    J Am Chem Soc; 2024 Jul; 146(26):17974-17985. PubMed ID: 38957136
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.