205 related articles for article (PubMed ID: 32622979)
1. Development of fluorescence polarization-based competition assay for nicotinamide N-methyltransferase.
Iyamu ID; Huang R
Anal Biochem; 2020 Sep; 604():113833. PubMed ID: 32622979
[TBL] [Abstract][Full Text] [Related]
2. Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity.
Neelakantan H; Vance V; Wang HL; McHardy SF; Watowich SJ
Biochemistry; 2017 Feb; 56(6):824-832. PubMed ID: 28121423
[TBL] [Abstract][Full Text] [Related]
3. Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ.
Lee HY; Suciu RM; Horning BD; Vinogradova EV; Ulanovskaya OA; Cravatt BF
Bioorg Med Chem Lett; 2018 Sep; 28(16):2682-2687. PubMed ID: 29731364
[TBL] [Abstract][Full Text] [Related]
4. A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.
van Haren MJ; Sastre Toraño J; Sartini D; Emanuelli M; Parsons RB; Martin NI
Biochemistry; 2016 Sep; 55(37):5307-15. PubMed ID: 27570878
[TBL] [Abstract][Full Text] [Related]
5. Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for Nicotinamide
Chen D; Li L; Diaz K; Iyamu ID; Yadav R; Noinaj N; Huang R
J Med Chem; 2019 Dec; 62(23):10783-10797. PubMed ID: 31724854
[TBL] [Abstract][Full Text] [Related]
6. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.
Neelakantan H; Vance V; Wetzel MD; Wang HL; McHardy SF; Finnerty CC; Hommel JD; Watowich SJ
Biochem Pharmacol; 2018 Jan; 147():141-152. PubMed ID: 29155147
[TBL] [Abstract][Full Text] [Related]
7. High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide
Policarpo RL; Decultot L; May E; Kuzmič P; Carlson S; Huang D; Chu V; Wright BA; Dhakshinamoorthy S; Kannt A; Rani S; Dittakavi S; Panarese JD; Gaudet R; Shair MD
J Med Chem; 2019 Nov; 62(21):9837-9873. PubMed ID: 31589440
[TBL] [Abstract][Full Text] [Related]
8. Potent Inhibition of Nicotinamide
Gao Y; van Haren MJ; Buijs N; Innocenti P; Zhang Y; Sartini D; Campagna R; Emanuelli M; Parsons RB; Jespers W; Gutiérrez-de-Terán H; van Westen GJP; Martin NI
J Med Chem; 2021 Sep; 64(17):12938-12963. PubMed ID: 34424711
[TBL] [Abstract][Full Text] [Related]
9. Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT).
Babault N; Allali-Hassani A; Li F; Fan J; Yue A; Ju K; Liu F; Vedadi M; Liu J; Jin J
J Med Chem; 2018 Feb; 61(4):1541-1551. PubMed ID: 29320176
[TBL] [Abstract][Full Text] [Related]
10. Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target.
Gao Y; Martin NI; van Haren MJ
Drug Discov Today; 2021 Nov; 26(11):2699-2706. PubMed ID: 34029690
[TBL] [Abstract][Full Text] [Related]
11. Novel Inhibitors of Nicotinamide-
Kannt A; Rajagopal S; Hallur MS; Swamy I; Kristam R; Dhakshinamoorthy S; Czech J; Zech G; Schreuder H; Ruf S
Molecules; 2021 Feb; 26(4):. PubMed ID: 33668468
[TBL] [Abstract][Full Text] [Related]
12. Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.
Swaminathan S; Birudukota S; Thakur MK; Parveen R; Kandan S; Juluri S; Shaik S; Anand NN; Burri RR; Kristam R; Hallur MS; Rajagopal S; Schreuder H; Langer T; Rudolph C; Ruf S; Dhakshinamoorthy S; Gosu R; Kannt A
Biochem Biophys Res Commun; 2017 Sep; 491(2):416-422. PubMed ID: 28720493
[TBL] [Abstract][Full Text] [Related]
13. Bisubstrate Inhibitors of Nicotinamide
Gao Y; van Haren MJ; Moret EE; Rood JJM; Sartini D; Salvucci A; Emanuelli M; Craveur P; Babault N; Jin J; Martin NI
J Med Chem; 2019 Jul; 62(14):6597-6614. PubMed ID: 31265285
[TBL] [Abstract][Full Text] [Related]
14. Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state.
van Haren MJ; Taig R; Kuppens J; Sastre Toraño J; Moret EE; Parsons RB; Sartini D; Emanuelli M; Martin NI
Org Biomol Chem; 2017 Aug; 15(31):6656-6667. PubMed ID: 28758655
[TBL] [Abstract][Full Text] [Related]
15. Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation.
Roberti A; Fernández AF; Fraga MF
Mol Metab; 2021 Mar; 45():101165. PubMed ID: 33453420
[TBL] [Abstract][Full Text] [Related]
16. Kinetic Mechanism of Nicotinamide N-Methyltransferase.
Loring HS; Thompson PR
Biochemistry; 2018 Sep; 57(38):5524-5532. PubMed ID: 30148963
[TBL] [Abstract][Full Text] [Related]
17. Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase.
Neelakantan H; Wang HY; Vance V; Hommel JD; McHardy SF; Watowich SJ
J Med Chem; 2017 Jun; 60(12):5015-5028. PubMed ID: 28548833
[TBL] [Abstract][Full Text] [Related]
18. Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase.
Sen S; Mondal S; Zheng L; Salinger AJ; Fast W; Weerapana E; Thompson PR
ACS Chem Biol; 2019 Apr; 14(4):613-618. PubMed ID: 30933557
[TBL] [Abstract][Full Text] [Related]
19. Macrocyclic peptides as allosteric inhibitors of nicotinamide
van Haren MJ; Zhang Y; Thijssen V; Buijs N; Gao Y; Mateuszuk L; Fedak FA; Kij A; Campagna R; Sartini D; Emanuelli M; Chlopicki S; Jongkees SAK; Martin NI
RSC Chem Biol; 2021 Oct; 2(5):1546-1555. PubMed ID: 34704059
[TBL] [Abstract][Full Text] [Related]
20. Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.
Ruf S; Hallur MS; Anchan NK; Swamy IN; Murugesan KR; Sarkar S; Narasimhulu LK; Putta VPRK; Shaik S; Chandrasekar DV; Mane VS; Kadnur SV; Suresh J; Bhamidipati RK; Singh M; Burri RR; Kristam R; Schreuder H; Czech J; Rudolph C; Marker A; Langer T; Mullangi R; Yura T; Gosu R; Kannt A; Dhakshinamoorthy S; Rajagopal S
Bioorg Med Chem Lett; 2018 Mar; 28(5):922-925. PubMed ID: 29433927
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
