158 related articles for article (PubMed ID: 32631508)
1. Synthesis and biological evaluation of novel isothiazoloquinoline quinone analogues.
Chen L; Xie YZ; Luo ZY; Liu LJ; Zou ZZ; Liu HD; Kong FR; Hao Y; Gao JL; Wang LL; Ma DY; Liu SY
Bioorg Med Chem Lett; 2020 Aug; 30(16):127286. PubMed ID: 32631508
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological activity of 1,4-quinone moiety attached to betulin derivatives as potent DT-diaphorase substrate.
Kadela-Tomanek M; Jastrzębska M; Marciniec K; Chrobak E; Bębenek E; Latocha M; Kuśmierz D; Boryczka S
Bioorg Chem; 2021 Jan; 106():104478. PubMed ID: 33272711
[TBL] [Abstract][Full Text] [Related]
3. 2-Substituted 3-methylnaphtho[1,2-b]furan-4,5-diones as novel L-shaped ortho-quinone substrates for NAD(P)H:quinone oxidoreductase (NQO1).
Bian J; Deng B; Xu L; Xu X; Wang N; Hu T; Yao Z; Du J; Yang L; Lei Y; Li X; Sun H; Zhang X; You Q
Eur J Med Chem; 2014 Jul; 82():56-67. PubMed ID: 24874653
[TBL] [Abstract][Full Text] [Related]
4. Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.
Zhang L; Liu P; Jiang Y; Fan D; He X; Zhang J; Luo B; Sui J; Luo Y; Fu X; Yang T
Eur J Med Chem; 2024 Jun; 272():116448. PubMed ID: 38704936
[TBL] [Abstract][Full Text] [Related]
5. Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.
Colucci MA; Moody CJ; Couch GD
Org Biomol Chem; 2008 Feb; 6(4):637-56. PubMed ID: 18264564
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of (±)-dunnione and its ortho-quinone analogues as substrates for NAD(P)H:quinone oxidoreductase 1 (NQO1).
Bian J; Xu L; Deng B; Qian X; Fan J; Yang X; Liu F; Xu X; Guo X; Li X; Sun H; You Q; Zhang X
Bioorg Med Chem Lett; 2015 Mar; 25(6):1244-8. PubMed ID: 25677663
[TBL] [Abstract][Full Text] [Related]
7. Betulin-1,4-quinone hybrids: Synthesis, anticancer activity and molecular docking study with NQO1 enzyme.
Kadela-Tomanek M; Bębenek E; Chrobak E; Marciniec K; Latocha M; Kuśmierz D; Jastrzębska M; Boryczka S
Eur J Med Chem; 2019 Sep; 177():302-315. PubMed ID: 31158746
[TBL] [Abstract][Full Text] [Related]
8. Development of novel amino-quinoline-5,8-dione derivatives as NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with potent antiproliferative activities.
Ling Y; Yang QX; Teng YN; Chen S; Gao WJ; Guo J; Hsu PL; Liu Y; Morris-Natschke SL; Hung CC; Lee KH
Eur J Med Chem; 2018 Jun; 154():199-209. PubMed ID: 29803003
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological evaluation of 3-(1-benzotriazole)-nor-β-lapachones as NQO1-directed antitumor agents.
Wu LQ; Ma X; Liu ZP
Bioorg Chem; 2021 Aug; 113():104995. PubMed ID: 34034133
[TBL] [Abstract][Full Text] [Related]
10. NAD(P)H:Quinone Oxidoreductase 1 (NQO1) as a Therapeutic and Diagnostic Target in Cancer.
Zhang K; Chen D; Ma K; Wu X; Hao H; Jiang S
J Med Chem; 2018 Aug; 61(16):6983-7003. PubMed ID: 29712428
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity.
Colucci MA; Reigan P; Siegel D; Chilloux A; Ross D; Moody CJ
J Med Chem; 2007 Nov; 50(23):5780-9. PubMed ID: 17944451
[TBL] [Abstract][Full Text] [Related]
12. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1).
Fryatt T; Pettersson HI; Gardipee WT; Bray KC; Green SJ; Slawin AM; Beall HD; Moody CJ
Bioorg Med Chem; 2004 Apr; 12(7):1667-87. PubMed ID: 15028260
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity.
Blunt CE; Torcuk C; Liu Y; Lewis W; Siegel D; Ross D; Moody CJ
Angew Chem Int Ed Engl; 2015 Jul; 54(30):8740-5. PubMed ID: 26096359
[TBL] [Abstract][Full Text] [Related]
14. Novel β-carboline-based indole-4,7-quinone derivatives as NAD(P)H: Quinone-oxidoreductase-1 inhibitor with potent antitumor activities by inducing reactive oxygen species, apoptosis, and DNA damage.
Guo Y; Xu L; Ling C; Yang T; Zheng W; Lv J; Guo Q; Chen B
Chem Biol Drug Des; 2020 Dec; 96(6):1433-1446. PubMed ID: 32592323
[TBL] [Abstract][Full Text] [Related]
15. Effects of 6-arylamino-5,8-quinolinediones and 6-chloro-7-arylamino-5,8-isoquinolinediones on NAD(P)H: quinone oxidoreductase (NQO1) activity and their cytotoxic potential.
Ryu CK; Jeong HJ; Lee SK; You HJ; Choi KU; Shim JY; Heo YH; Lee CO
Arch Pharm Res; 2001 Oct; 24(5):390-6. PubMed ID: 11693537
[TBL] [Abstract][Full Text] [Related]
16. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.
den Braver-Sewradj SP; den Braver MW; Toorneman RM; van Leeuwen S; Zhang Y; Dekker SJ; Vermeulen NPE; Commandeur JNM; Vos JC
Chem Res Toxicol; 2018 Feb; 31(2):116-126. PubMed ID: 29281794
[TBL] [Abstract][Full Text] [Related]
17. Indolequinone antitumor agents: correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity.
Beall HD; Winski S; Swann E; Hudnott AR; Cotterill AS; O'Sullivan N; Green SJ; Bien R; Siegel D; Ross D; Moody CJ
J Med Chem; 1998 Nov; 41(24):4755-66. PubMed ID: 9822546
[TBL] [Abstract][Full Text] [Related]
18. Indolequinone antitumor agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase. Part 2.
Swann E; Barraja P; Oberlander AM; Gardipee WT; Hudnott AR; Beall HD; Moody CJ
J Med Chem; 2001 Sep; 44(20):3311-9. PubMed ID: 11563930
[TBL] [Abstract][Full Text] [Related]
19. Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1.
Newsome JJ; Hassani M; Swann E; Bibby JM; Beall HD; Moody CJ
Bioorg Med Chem; 2013 Jun; 21(11):2999-3009. PubMed ID: 23635904
[TBL] [Abstract][Full Text] [Related]
20. Application of cation-π interactions in enzyme-substrate binding: Design, synthesis, biological evaluation, and molecular dynamics insights of novel hydrophilic substrates for NQO1.
Gong Q; Yu Q; Wang N; Hu J; Wang P; Yang F; Li T; You Q; Li X; Zhang X
Eur J Med Chem; 2021 Oct; 221():113515. PubMed ID: 33984806
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]