BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 32636302)

  • 1. The molecular basis for immune dysregulation by the hyperactivated E62K mutant of the GTPase RAC2.
    Arrington ME; Temple B; Schaefer A; Campbell SL
    J Biol Chem; 2020 Aug; 295(34):12130-12142. PubMed ID: 32636302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects.
    Hsu AP; Donkó A; Arrington ME; Swamydas M; Fink D; Das A; Escobedo O; Bonagura V; Szabolcs P; Steinberg HN; Bergerson J; Skoskiewicz A; Makhija M; Davis J; Foruraghi L; Palmer C; Fuleihan RL; Church JA; Bhandoola A; Lionakis MS; Campbell S; Leto TL; Kuhns DB; Holland SM
    Blood; 2019 May; 133(18):1977-1988. PubMed ID: 30723080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors.
    Kwofie MA; Skowronski J
    J Biol Chem; 2008 Feb; 283(6):3088-3096. PubMed ID: 18056264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.
    Ingram DA; Hiatt K; King AJ; Fisher L; Shivakumar R; Derstine C; Wenning MJ; Diaz B; Travers JB; Hood A; Marshall M; Williams DA; Clapp DW
    J Exp Med; 2001 Jul; 194(1):57-69. PubMed ID: 11435472
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation.
    Yin G; Kistler S; George SD; Kuhlmann N; Garvey L; Huynh M; Bagni RK; Lammers M; Der CJ; Campbell SL
    J Biol Chem; 2017 Mar; 292(11):4446-4456. PubMed ID: 28154176
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative functional analysis of the Rac GTPases.
    Haeusler LC; Blumenstein L; Stege P; Dvorsky R; Ahmadian MR
    FEBS Lett; 2003 Dec; 555(3):556-60. PubMed ID: 14675773
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases.
    Ren Y; Li R; Zheng Y; Busch H
    J Biol Chem; 1998 Dec; 273(52):34954-60. PubMed ID: 9857026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
    Wang L; Zhu K; Zheng Y
    Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2.
    Mahankali M; Peng HJ; Henkels KM; Dinauer MC; Gomez-Cambronero J
    Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19617-22. PubMed ID: 22106281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural requirements for PAK activation by Rac GTPases.
    Knaus UG; Wang Y; Reilly AM; Warnock D; Jackson JH
    J Biol Chem; 1998 Aug; 273(34):21512-8. PubMed ID: 9705280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.
    Pick E
    Small GTPases; 2014; 5():e27952. PubMed ID: 24598074
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox).
    Ahmed S; Prigmore E; Govind S; Veryard C; Kozma R; Wientjes FB; Segal AW; Lim L
    J Biol Chem; 1998 Jun; 273(25):15693-701. PubMed ID: 9624165
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
    Buchsbaum RJ; Connolly BA; Feig LA
    J Biol Chem; 2003 May; 278(21):18833-41. PubMed ID: 12531897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis.
    Spoerner M; Hozsa C; Poetzl JA; Reiss K; Ganser P; Geyer M; Kalbitzer HR
    J Biol Chem; 2010 Dec; 285(51):39768-78. PubMed ID: 20937837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combined Immunodeficiency Caused by a Novel De Novo Gain-of-Function RAC2 Mutation.
    Zhang L; Chen Z; Li W; Liu Q; Wang Y; Chen X; Tian Z; Yang Q; An Y; Zhang Z; Mao H; Tang X; Lv G; Zhao X
    J Clin Immunol; 2022 Aug; 42(6):1280-1292. PubMed ID: 35596857
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction.
    Kowluru A
    Small GTPases; 2021; 12(5-6):323-335. PubMed ID: 32867592
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase.
    Ando S; Kaibuchi K; Sasaki T; Hiraoka K; Nishiyama T; Mizuno T; Asada M; Nunoi H; Matsuda I; Matsuura Y
    J Biol Chem; 1992 Dec; 267(36):25709-13. PubMed ID: 1464587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new function of p120-GTPase-activating protein. Prevention of the guanine nucleotide exchange factor-stimulated nucleotide exchange on the active form of Ha-ras p21.
    Giglione C; Parrini MC; Baouz S; Bernardi A; Parmeggiani A
    J Biol Chem; 1997 Oct; 272(40):25128-34. PubMed ID: 9312123
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins.
    Zhang B; Zhang Y; Wang Z; Zheng Y
    J Biol Chem; 2000 Aug; 275(33):25299-307. PubMed ID: 10843989
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production.
    Matono R; Miyano K; Kiyohara T; Sumimoto H
    J Biol Chem; 2014 Sep; 289(36):24874-84. PubMed ID: 25056956
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.