BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 32645923)

  • 1. CPPF, A Novel Microtubule Targeting Anticancer Agent, Inhibits the Growth of a Wide Variety of Cancers.
    Han HJ; Park C; Hwang J; N R T; Kim SO; Han J; Woo M; B S; Ryoo IJ; Lee KH; Cha-Molstad H; Kwon YT; Kim BY; Soung NK
    Int J Mol Sci; 2020 Jul; 21(13):. PubMed ID: 32645923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells.
    Dinić J; Ríos-Luci C; Karpaviciene I; Cikotiene I; Fernandes MX; Pešić M; Padrón JM
    Invest New Drugs; 2020 Jun; 38(3):584-598. PubMed ID: 31177401
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
    Wong VK; Chiu P; Chung SS; Chow LM; Zhao YZ; Yang BB; Ko BC
    Clin Cancer Res; 2005 Aug; 11(16):6002-11. PubMed ID: 16115945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-APCAs, the Novel Microtubule Targeting Agents Active Against Distinct Cancer Cell Lines.
    Boichuk S; Galembikova A; Bikinieva F; Dunaev P; Aukhadieva A; Syuzov K; Zykova S; Igidov N; Ksenofontov A; Bocharov P
    Molecules; 2021 Jan; 26(3):. PubMed ID: 33503939
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell.
    Hasanpourghadi M; Karthikeyan C; Pandurangan AK; Looi CY; Trivedi P; Kobayashi K; Tanaka K; Wong WF; Mustafa MR
    J Exp Clin Cancer Res; 2016 Mar; 35():58. PubMed ID: 27030360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
    Bai Z; Liu X; Guan Q; Ding N; Wei Q; Tong B; Zhao M; Zhang W; Ma L
    Chem Biol Interact; 2020 Jan; 315():108886. PubMed ID: 31682804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Systematic Review on Cytotoxic and Anticancer Potential of N-Substituted Isatins as Novel Class of Compounds Useful in Multidrug-Resistant Cancer Therapy: In Silico and In Vitro Analysis.
    Gupta AK; Tulsyan S; Bharadwaj M; Mehrotra R
    Top Curr Chem (Cham); 2019 May; 377(3):15. PubMed ID: 31073777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance.
    Manzoor S; Bilal A; Khan S; Ullah R; Iftikhar S; Emwas AH; Alazmi M; Gao X; Jawaid A; Saleem RSZ; Faisal A
    Sci Rep; 2018 Feb; 8(1):3305. PubMed ID: 29459693
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lx2-32c, a novel taxane derivative, exerts anti-resistance activity by initiating intrinsic apoptosis pathway in vitro and inhibits the growth of resistant tumor in vivo.
    Zhou Q; Li Y; Jin J; Lang L; Zhu Z; Fang W; Chen X
    Biol Pharm Bull; 2012; 35(12):2170-9. PubMed ID: 23207769
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe.
    Bai Z; Gao M; Zhang H; Guan Q; Xu J; Li Y; Qi H; Li Z; Zuo D; Zhang W; Wu Y
    Cancer Lett; 2017 Aug; 402():81-92. PubMed ID: 28576750
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
    Reddy MV; Mallireddigari MR; Pallela VR; Cosenza SC; Billa VK; Akula B; Subbaiah DR; Bharathi EV; Padgaonkar A; Lv H; Gallo JM; Reddy EP
    J Med Chem; 2013 Jul; 56(13):5562-86. PubMed ID: 23750455
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents.
    Wang RC; Chen X; Parissenti AM; Joy AA; Tuszynski J; Brindley DN; Wang Z
    PLoS One; 2017; 12(8):e0182400. PubMed ID: 28787019
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport.
    Zang X; Wang G; Cai Q; Zheng X; Zhang J; Chen Q; Wu B; Zhu X; Hao H; Zhou F
    Drug Metab Dispos; 2018 May; 46(5):542-551. PubMed ID: 29523600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
    Cai P; Lu P; Sharom FJ; Fang WS
    Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
    Liou JP; Hsu KS; Kuo CC; Chang CY; Chang JY
    J Pharmacol Exp Ther; 2007 Oct; 323(1):398-405. PubMed ID: 17660383
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function.
    Lindamulage IK; Vu HY; Karthikeyan C; Knockleby J; Lee YF; Trivedi P; Lee H
    Sci Rep; 2017 Aug; 7(1):10298. PubMed ID: 28860494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors.
    Ning N; Yu Y; Wu M; Zhang R; Zhang T; Zhu C; Huang L; Yun CH; Benes CH; Zhang J; Deng X; Chen Q; Ren R
    Cancer Res; 2018 Oct; 78(20):5949-5957. PubMed ID: 30135190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
    Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells.
    Podolski-Renić A; Banković J; Dinić J; Ríos-Luci C; Fernandes MX; Ortega N; Kovačević-Grujičić N; Martín VS; Padrón JM; Pešić M
    Eur J Pharm Sci; 2017 Jul; 105():159-168. PubMed ID: 28502672
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.
    Grohmann C; Walker F; Devlin M; Luo MX; Chüeh AC; Doherty J; Vaillant F; Ho GY; Wakefield MJ; Weeden CE; Kamili A; Murray J; Po'uha ST; Weinstock J; Kane SR; Faux MC; Broekhuizen E; Zheng Y; Shield-Artin K; Kershaw NJ; Tan CW; Witchard HM; Ebert G; Charman SA; Street I; Kavallaris M; Haber M; Fletcher JI; Asselin-Labat ML; Scott CL; Visvader JE; Lindeman GJ; Watson KG; Burgess AW; Lessene G
    Cell Death Dis; 2021 Mar; 12(3):268. PubMed ID: 33712556
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.