250 related articles for article (PubMed ID: 32653916)
1. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
Nada S; Okada M
J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for the assembly of the Ragulator-Rag GTPase complex.
Yonehara R; Nada S; Nakai T; Nakai M; Kitamura A; Ogawa A; Nakatsumi H; Nakayama KI; Li S; Standley DM; Yamashita E; Nakagawa A; Okada M
Nat Commun; 2017 Nov; 8(1):1625. PubMed ID: 29158492
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1.
Zhang T; Wang R; Wang Z; Wang X; Wang F; Ding J
Nat Commun; 2017 Nov; 8(1):1394. PubMed ID: 29123114
[TBL] [Abstract][Full Text] [Related]
4. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Sancak Y; Bar-Peled L; Zoncu R; Markhard AL; Nada S; Sabatini DM
Cell; 2010 Apr; 141(2):290-303. PubMed ID: 20381137
[TBL] [Abstract][Full Text] [Related]
5. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
[TBL] [Abstract][Full Text] [Related]
6. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
Oshiro N; Rapley J; Avruch J
J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
[TBL] [Abstract][Full Text] [Related]
7. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
Shibutani S; Okazaki H; Iwata H
J Biol Chem; 2017 Nov; 292(44):18052-18061. PubMed ID: 28808055
[TBL] [Abstract][Full Text] [Related]
8. Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity.
Yao Y; Hong S; Ikeda T; Mori H; MacDougald OA; Nada S; Okada M; Inoki K
Mol Cell; 2020 Nov; 80(3):437-451.e6. PubMed ID: 33157014
[TBL] [Abstract][Full Text] [Related]
9. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
Shen K; Sabatini DM
Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
[TBL] [Abstract][Full Text] [Related]
10. Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
Cui Z; Napolitano G; de Araujo MEG; Esposito A; Monfregola J; Huber LA; Ballabio A; Hurley JH
Nature; 2023 Feb; 614(7948):572-579. PubMed ID: 36697823
[TBL] [Abstract][Full Text] [Related]
11. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
Jung J; Genau HM; Behrends C
Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
[TBL] [Abstract][Full Text] [Related]
12. Rag GTPase in amino acid signaling.
Kim J; Kim E
Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
[TBL] [Abstract][Full Text] [Related]
13. Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex.
Su MY; Morris KL; Kim DJ; Fu Y; Lawrence R; Stjepanovic G; Zoncu R; Hurley JH
Mol Cell; 2017 Dec; 68(5):835-846.e3. PubMed ID: 29107538
[TBL] [Abstract][Full Text] [Related]
14. A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.
Lawrence RE; Cho KF; Rappold R; Thrun A; Tofaute M; Kim DJ; Moldavski O; Hurley JH; Zoncu R
Nat Cell Biol; 2018 Sep; 20(9):1052-1063. PubMed ID: 30061680
[TBL] [Abstract][Full Text] [Related]
15. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Egri SB; Ouch C; Chou HT; Yu Z; Song K; Xu C; Shen K
Mol Cell; 2022 May; 82(10):1836-1849.e5. PubMed ID: 35338845
[TBL] [Abstract][Full Text] [Related]
16. Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation.
Suryawan A; Davis TA
J Nutr; 2018 Jun; 148(6):825-833. PubMed ID: 29796625
[TBL] [Abstract][Full Text] [Related]
17. Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.
Ögmundsdóttir MH; Heublein S; Kazi S; Reynolds B; Visvalingam SM; Shaw MK; Goberdhan DC
PLoS One; 2012; 7(5):e36616. PubMed ID: 22574197
[TBL] [Abstract][Full Text] [Related]
18. Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.
Shi H; Chapman NM; Wen J; Guy C; Long L; Dhungana Y; Rankin S; Pelletier S; Vogel P; Wang H; Peng J; Guan KL; Chi H
Immunity; 2019 Dec; 51(6):1012-1027.e7. PubMed ID: 31668641
[TBL] [Abstract][Full Text] [Related]
19. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
Bar-Peled L; Schweitzer LD; Zoncu R; Sabatini DM
Cell; 2012 Sep; 150(6):1196-208. PubMed ID: 22980980
[TBL] [Abstract][Full Text] [Related]
20. Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D; Yang Q; Wang H; Melick CH; Navlani R; Frank AR; Jewell JL
J Biol Chem; 2020 Mar; 295(10):2890-2899. PubMed ID: 32019866
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
