BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 32662825)

  • 1. Targeting MmpL3 for anti-tuberculosis drug development.
    Bolla JR
    Biochem Soc Trans; 2020 Aug; 48(4):1463-1472. PubMed ID: 32662825
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria.
    Fay A; Czudnochowski N; Rock JM; Johnson JR; Krogan NJ; Rosenberg O; Glickman MS
    mBio; 2019 Jun; 10(3):. PubMed ID: 31239378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine.
    Su CC; Klenotic PA; Bolla JR; Purdy GE; Robinson CV; Yu EW
    Proc Natl Acad Sci U S A; 2019 Jun; 116(23):11241-11246. PubMed ID: 31113875
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MmpL3 inhibitors as antituberculosis drugs.
    Shao M; McNeil M; Cook GM; Lu X
    Eur J Med Chem; 2020 Aug; 200():112390. PubMed ID: 32447196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis.
    Belardinelli JM; Yazidi A; Yang L; Fabre L; Li W; Jacques B; Angala SK; Rouiller I; Zgurskaya HI; Sygusch J; Jackson M
    ACS Infect Dis; 2016 Oct; 2(10):702-713. PubMed ID: 27737557
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.
    Tahlan K; Wilson R; Kastrinsky DB; Arora K; Nair V; Fischer E; Barnes SW; Walker JR; Alland D; Barry CE; Boshoff HI
    Antimicrob Agents Chemother; 2012 Apr; 56(4):1797-809. PubMed ID: 22252828
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A piperidinol-containing molecule is active against
    Dupont C; Chen Y; Xu Z; Roquet-Banères F; Blaise M; Witt AK; Dubar F; Biot C; Guérardel Y; Maurer FP; Chng SS; Kremer L
    J Biol Chem; 2019 Nov; 294(46):17512-17523. PubMed ID: 31562241
    [No Abstract]   [Full Text] [Related]  

  • 8. Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
    Williams JT; Haiderer ER; Coulson GB; Conner KN; Ellsworth E; Chen C; Alvarez-Cabrera N; Li W; Jackson M; Dick T; Abramovitch RB
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31405862
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1
    Korycka-Machała M; Viljoen A; Pawełczyk J; Borówka P; Dziadek B; Gobis K; Brzostek A; Kawka M; Blaise M; Strapagiel D; Kremer L; Dziadek J
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31332069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3.
    Hu T; Yang X; Liu F; Sun S; Xiong Z; Liang J; Yang X; Wang H; Yang X; Guddat LW; Yang H; Rao Z; Zhang B
    Structure; 2022 Oct; 30(10):1395-1402.e4. PubMed ID: 35981536
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis.
    Li W; Upadhyay A; Fontes FL; North EJ; Wang Y; Crans DC; Grzegorzewicz AE; Jones V; Franzblau SG; Lee RE; Crick DC; Jackson M
    Antimicrob Agents Chemother; 2014 Nov; 58(11):6413-23. PubMed ID: 25136022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat Tuberculosis.
    Umare MD; Khedekar PB; Chikhale RV
    ChemMedChem; 2021 Oct; 16(20):3136-3148. PubMed ID: 34288519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipid transport in Mycobacterium tuberculosis and its implications in virulence and drug development.
    Bailo R; Bhatt A; Aínsa JA
    Biochem Pharmacol; 2015 Aug; 96(3):159-67. PubMed ID: 25986884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MmpL3 Inhibitors: Diverse Chemical Scaffolds Inhibit the Same Target.
    Poce G; Consalvi S; Biava M
    Mini Rev Med Chem; 2016; 16(16):1274-1283. PubMed ID: 26776226
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MmpL3 is the flippase for mycolic acids in mycobacteria.
    Xu Z; Meshcheryakov VA; Poce G; Chng SS
    Proc Natl Acad Sci U S A; 2017 Jul; 114(30):7993-7998. PubMed ID: 28698380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acetylation of trehalose mycolates is required for efficient MmpL-mediated membrane transport in Corynebacterineae.
    Yamaryo-Botte Y; Rainczuk AK; Lea-Smith DJ; Brammananth R; van der Peet PL; Meikle P; Ralton JE; Rupasinghe TW; Williams SJ; Coppel RL; Crellin PK; McConville MJ
    ACS Chem Biol; 2015 Mar; 10(3):734-46. PubMed ID: 25427102
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport.
    Su CC; Klenotic PA; Cui M; Lyu M; Morgan CE; Yu EW
    PLoS Biol; 2021 Aug; 19(8):e3001370. PubMed ID: 34383749
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MmpL3 a potential new target for development of novel anti-tuberculosis drugs.
    Rayasam GV
    Expert Opin Ther Targets; 2014 Mar; 18(3):247-56. PubMed ID: 24325728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter.
    Zheng H; Williams JT; Coulson GB; Haiderer ER; Abramovitch RB
    Antimicrob Agents Chemother; 2018 Jul; 62(7):. PubMed ID: 29661875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO.
    Yang X; Hu T; Yang X; Xu W; Yang H; Guddat LW; Zhang B; Rao Z
    J Mol Biol; 2020 Jul; 432(16):4426-4434. PubMed ID: 32512002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.