BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 32663591)

  • 1. Shikonin induces tumor apoptosis in glioma cells via endoplasmic reticulum stress, and Bax/Bak mediated mitochondrial outer membrane permeability.
    Ma X; Yu M; Hao C; Yang W
    J Ethnopharmacol; 2020 Dec; 263():113059. PubMed ID: 32663591
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel multiple apoptotic mechanism of shikonin in human glioma cells.
    Chen CH; Lin ML; Ong PL; Yang JT
    Ann Surg Oncol; 2012 Sep; 19(9):3097-106. PubMed ID: 22446899
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway.
    Gara RK; Srivastava VK; Duggal S; Bagga JK; Bhatt M; Sanyal S; Mishra DP
    J Biomed Sci; 2015 Apr; 22(1):26. PubMed ID: 25879420
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling.
    Yahiro K; Morinaga N; Moss J; Noda M
    Microb Pathog; 2010 Oct; 49(4):153-63. PubMed ID: 20561923
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine.
    Seervi M; Rani A; Sharma AK; Santhosh Kumar TR
    Biomed Pharmacother; 2018 Oct; 106():200-209. PubMed ID: 29960166
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shikonin induces apoptosis and prosurvival autophagy in human melanoma A375 cells via ROS-mediated ER stress and p38 pathways.
    Liu Y; Kang X; Niu G; He S; Zhang T; Bai Y; Li Y; Hao H; Chen C; Shou Z; Li B
    Artif Cells Nanomed Biotechnol; 2019 Dec; 47(1):626-635. PubMed ID: 30873870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of PI3K/Akt signaling by synthetic bichalcone analog TSWU-CD4 induces ER stress- and Bax/Bak-mediated apoptosis of cancer cells.
    Lin ML; Chen SS; Huang RY; Lu YC; Liao YR; Reddy MV; Lee CC; Wu TS
    Apoptosis; 2014 Nov; 19(11):1637-53. PubMed ID: 25183449
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress.
    Yang J; Wang Z; Chen DL
    Biomed Pharmacother; 2017 Sep; 93():1343-1357. PubMed ID: 28753907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
    Jing H; Sun W; Fan J; Zhang Y; Yang J; Jia J; Li J; Guo J; Luo S; Zheng Y
    Mol Med Rep; 2016 Apr; 13(4):3009-16. PubMed ID: 26935874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.
    Siu WP; Pun PB; Latchoumycandane C; Boelsterli UA
    Toxicol Appl Pharmacol; 2008 Mar; 227(3):451-61. PubMed ID: 18191430
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway.
    Huang WR; Zhang Y; Tang X
    Molecules; 2014 Jun; 19(6):7785-97. PubMed ID: 24962386
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A; Brady NR
    J Biol Chem; 2015 Sep; 290(36):22005-18. PubMed ID: 26134559
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death.
    Darling NJ; Balmanno K; Cook SJ
    PLoS One; 2017; 12(9):e0184907. PubMed ID: 28931068
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The functional role of Bax/Bak in palmitate-induced lipoapoptosis.
    Zhang E; Lu X; Yin S; Yan M; Lu S; Fan L; Hu H
    Food Chem Toxicol; 2019 Jan; 123():268-274. PubMed ID: 30408539
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rutin hydrate inhibits apoptosis in the brains of cadmium chloride-treated rats via preserving the mitochondrial integrity and inhibiting endoplasmic reticulum stress.
    Mostafa DG; Khaleel EF; Badi RM; Abdel-Aleem GA; Abdeen HM
    Neurol Res; 2019 Jul; 41(7):594-608. PubMed ID: 30973085
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection.
    Niu X; Brahmbhatt H; Mergenthaler P; Zhang Z; Sang J; Daude M; Ehlert FGR; Diederich WE; Wong E; Zhu W; Pogmore J; Nandy JP; Satyanarayana M; Jimmidi RK; Arya P; Leber B; Lin J; Culmsee C; Yi J; Andrews DW
    Cell Chem Biol; 2017 Apr; 24(4):493-506.e5. PubMed ID: 28392146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Shikonin Protects PC12 Cells Against β-amyloid Peptide-Induced Cell Injury Through Antioxidant and Antiapoptotic Activities.
    Tong Y; Bai L; Gong R; Chuan J; Duan X; Zhu Y
    Sci Rep; 2018 Jan; 8(1):26. PubMed ID: 29311595
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shikonin inhibits the proliferation and induces the apoptosis of human HepG2 cells.
    Yingkun N; Lvsong Z; Huimin Y
    Can J Physiol Pharmacol; 2010 Dec; 88(12):1138-46. PubMed ID: 21164560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH; Lin R; Perez-Soler R
    Mol Pharmacol; 2008 Sep; 74(3):793-806. PubMed ID: 18524889
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis.
    Han W; Xie J; Li L; Liu Z; Hu X
    Apoptosis; 2009 May; 14(5):674-86. PubMed ID: 19288276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.