239 related articles for article (PubMed ID: 32666270)
1. miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.
Readhead B; Haure-Mirande JV; Mastroeni D; Audrain M; Fanutza T; Kim SH; Blitzer RD; Gandy S; Dudley JT; Ehrlich ME
Acta Neuropathol; 2020 Sep; 140(3):295-315. PubMed ID: 32666270
[TBL] [Abstract][Full Text] [Related]
2. Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology.
Rothman SM; Tanis KQ; Gandhi P; Malkov V; Marcus J; Pearson M; Stevens R; Gilliland J; Ware C; Mahadomrongkul V; O'Loughlin E; Zeballos G; Smith R; Howell BJ; Klappenbach J; Kennedy M; Mirescu C
J Neuroinflammation; 2018 Sep; 15(1):256. PubMed ID: 30189875
[TBL] [Abstract][Full Text] [Related]
3. Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead B; Haure-Mirande JV; Funk CC; Richards MA; Shannon P; Haroutunian V; Sano M; Liang WS; Beckmann ND; Price ND; Reiman EM; Schadt EE; Ehrlich ME; Gandy S; Dudley JT
Neuron; 2018 Jul; 99(1):64-82.e7. PubMed ID: 29937276
[TBL] [Abstract][Full Text] [Related]
4. Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.
Haure-Mirande JV; Wang M; Audrain M; Fanutza T; Kim SH; Heja S; Readhead B; Dudley JT; Blitzer RD; Schadt EE; Zhang B; Gandy S; Ehrlich ME
Mol Psychiatry; 2019 Mar; 24(3):431-446. PubMed ID: 30283032
[TBL] [Abstract][Full Text] [Related]
5. Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice.
Fitz NF; Wolfe CM; Playso BE; Biedrzycki RJ; Lu Y; Nam KN; Lefterov I; Koldamova R
Mol Neurodegener; 2020 Jul; 15(1):41. PubMed ID: 32703241
[TBL] [Abstract][Full Text] [Related]
6. The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.
Collins JM; King AE; Woodhouse A; Kirkcaldie MT; Vickers JC
Exp Neurol; 2015 May; 267():219-29. PubMed ID: 25747037
[TBL] [Abstract][Full Text] [Related]
7. Alzheimer's disease amyloid-β pathology in the lens of the eye.
Moncaster JA; Moir RD; Burton MA; Chadwick O; Minaeva O; Alvarez VE; Ericsson M; Clark JI; McKee AC; Tanzi RE; Goldstein LE
Exp Eye Res; 2022 Aug; 221():108974. PubMed ID: 35202705
[TBL] [Abstract][Full Text] [Related]
8. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
[TBL] [Abstract][Full Text] [Related]
9. Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases.
Wirths O; Bethge T; Marcello A; Harmeier A; Jawhar S; Lucassen PJ; Multhaup G; Brody DL; Esparza T; Ingelsson M; Kalimo H; Lannfelt L; Bayer TA
J Neural Transm (Vienna); 2010 Jan; 117(1):85-96. PubMed ID: 19823761
[TBL] [Abstract][Full Text] [Related]
10. Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model.
Blacher E; Dadali T; Bespalko A; Haupenthal VJ; Grimm MO; Hartmann T; Lund FE; Stein R; Levy A
Ann Neurol; 2015 Jul; 78(1):88-103. PubMed ID: 25893674
[TBL] [Abstract][Full Text] [Related]
11. Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.
Ma C; Hunt JB; Kovalenko A; Liang H; Selenica MB; Orr MB; Zhang B; Gensel JC; Feola DJ; Gordon MN; Morgan D; Bickford PC; Lee DC
Front Immunol; 2021; 12():628156. PubMed ID: 34046031
[TBL] [Abstract][Full Text] [Related]
12. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Xia D; Lianoglou S; Sandmann T; Calvert M; Suh JH; Thomsen E; Dugas J; Pizzo ME; DeVos SL; Earr TK; Lin CC; Davis S; Ha C; Leung AW; Nguyen H; Chau R; Yulyaningsih E; Lopez I; Solanoy H; Masoud ST; Liang CC; Lin K; Astarita G; Khoury N; Zuchero JY; Thorne RG; Shen K; Miller S; Palop JJ; Garceau D; Sasner M; Whitesell JD; Harris JA; Hummel S; Gnörich J; Wind K; Kunze L; Zatcepin A; Brendel M; Willem M; Haass C; Barnett D; Zimmer TS; Orr AG; Scearce-Levie K; Lewcock JW; Di Paolo G; Sanchez PE
Mol Neurodegener; 2022 Jun; 17(1):41. PubMed ID: 35690868
[TBL] [Abstract][Full Text] [Related]
13. Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease.
Pandey RS; Graham L; Uyar A; Preuss C; Howell GR; Carter GW
Mol Neurodegener; 2019 Dec; 14(1):50. PubMed ID: 31878951
[TBL] [Abstract][Full Text] [Related]
14. Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer's disease.
Sakakibara Y; Sekiya M; Saito T; Saido TC; Iijima KM
BMC Neurosci; 2019 Mar; 20(1):13. PubMed ID: 30894120
[TBL] [Abstract][Full Text] [Related]
15. Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
Haure-Mirande JV; Audrain M; Fanutza T; Kim SH; Klein WL; Glabe C; Readhead B; Dudley JT; Blitzer RD; Wang M; Zhang B; Schadt EE; Gandy S; Ehrlich ME
Acta Neuropathol; 2017 Nov; 134(5):769-788. PubMed ID: 28612290
[TBL] [Abstract][Full Text] [Related]
16. Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer's Disease.
Weissmann R; Hüttenrauch M; Kacprowski T; Bouter Y; Pradier L; Bayer TA; Kuss AW; Wirths O
J Alzheimers Dis; 2016; 50(2):397-409. PubMed ID: 26639971
[TBL] [Abstract][Full Text] [Related]
17. First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression.
Cummings DM; Liu W; Portelius E; Bayram S; Yasvoina M; Ho SH; Smits H; Ali SS; Steinberg R; Pegasiou CM; James OT; Matarin M; Richardson JC; Zetterberg H; Blennow K; Hardy JA; Salih DA; Edwards FA
Brain; 2015 Jul; 138(Pt 7):1992-2004. PubMed ID: 25981962
[TBL] [Abstract][Full Text] [Related]
18. Over-expression of miR-34a induces rapid cognitive impairment and Alzheimer's disease-like pathology.
Sarkar S; Engler-Chiurazzi EB; Cavendish JZ; Povroznik JM; Russell AE; Quintana DD; Mathers PH; Simpkins JW
Brain Res; 2019 Oct; 1721():146327. PubMed ID: 31295467
[TBL] [Abstract][Full Text] [Related]
19. Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease.
Wang X; Xie Y; Fan X; Wu X; Wang D; Zhu L
Alzheimers Res Ther; 2024 Jun; 16(1):121. PubMed ID: 38831312
[TBL] [Abstract][Full Text] [Related]
20. Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.
Zhou FQ; Jiang J; Griffith CM; Patrylo PR; Cai H; Chu Y; Yan XX
Alzheimers Res Ther; 2018 Apr; 10(1):40. PubMed ID: 29690919
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]