168 related articles for article (PubMed ID: 32667058)
1. Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells.
Abdulrahman N; Siveen KS; Joseph JM; Osman A; Yalcin HC; Hasan A; Uddin S; Mraiche F
J Pharm Pharmacol; 2020 Nov; 72(11):1536-1545. PubMed ID: 32667058
[TBL] [Abstract][Full Text] [Related]
2. Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner.
Roffé M; Lupinacci FC; Soares LC; Hajj GN; Martins VR
Cell Signal; 2015 Aug; 27(8):1630-42. PubMed ID: 25889895
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of p90 ribosomal S6 kinase attenuates cell migration and proliferation of the human lung adenocarcinoma through phospho-GSK-3β and osteopontin.
Abdulrahman N; Jaballah M; Poomakkoth N; Riaz S; Abdelaziz S; Issa A; Mraiche F
Mol Cell Biochem; 2016 Jul; 418(1-2):21-9. PubMed ID: 27236820
[TBL] [Abstract][Full Text] [Related]
4. The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.
Neise D; Sohn D; Stefanski A; Goto H; Inagaki M; Wesselborg S; Budach W; Stühler K; Jänicke RU
Cell Death Dis; 2013 Oct; 4(10):e859. PubMed ID: 24136223
[TBL] [Abstract][Full Text] [Related]
5. RSK Inhibition Induces Apoptosis by Downregulating Protein Synthesis in a Variety of Acute Myeloid Leukemia Cell Lines.
Katayama K; Nishihata A
Biol Pharm Bull; 2021 Dec; 44(12):1843-1850. PubMed ID: 34602526
[TBL] [Abstract][Full Text] [Related]
6. Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.
Pambid MR; Berns R; Adomat HH; Hu K; Triscott J; Maurer N; Zisman N; Ramaswamy V; Hawkins CE; Taylor MD; Dunham C; Guns E; Dunn SE
Pediatr Blood Cancer; 2014 Jan; 61(1):107-15. PubMed ID: 23940083
[TBL] [Abstract][Full Text] [Related]
7. BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.
Sapkota GP; Cummings L; Newell FS; Armstrong C; Bain J; Frodin M; Grauert M; Hoffmann M; Schnapp G; Steegmaier M; Cohen P; Alessi DR
Biochem J; 2007 Jan; 401(1):29-38. PubMed ID: 17040210
[TBL] [Abstract][Full Text] [Related]
8. Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study.
Casalvieri KA; Matheson CJ; Backos DS; Reigan P
Bioorg Med Chem; 2020 Mar; 28(5):115303. PubMed ID: 31982240
[TBL] [Abstract][Full Text] [Related]
9. Antitumor effects of BI-D1870 on human oral squamous cell carcinoma.
Chiu CF; Bai LY; Kapuriya N; Peng SY; Wu CY; Sargeant AM; Chen MY; Weng JR
Cancer Chemother Pharmacol; 2014 Feb; 73(2):237-47. PubMed ID: 24241211
[TBL] [Abstract][Full Text] [Related]
10. A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.
Edgar AJ; Trost M; Watts C; Zaru R
Biosci Rep; 2014 Feb; 34(1):. PubMed ID: 27919044
[TBL] [Abstract][Full Text] [Related]
11. RSK2(Ser227) at N-terminal kinase domain is a potential therapeutic target for multiple myeloma.
Shimura Y; Kuroda J; Ri M; Nagoshi H; Yamamoto-Sugitani M; Kobayashi T; Kiyota M; Nakayama R; Mizutani S; Chinen Y; Sakamoto N; Matsumoto Y; Horiike S; Shiotsu Y; Iida S; Taniwaki M
Mol Cancer Ther; 2012 Dec; 11(12):2600-9. PubMed ID: 23012246
[TBL] [Abstract][Full Text] [Related]
12. The ribosomal S6 kinase inhibitor BI-D1870 ameliorated experimental autoimmune encephalomyelitis in mice.
Takada I; Yogiashi Y; Makishima M
Immunobiology; 2016 Feb; 221(2):188-92. PubMed ID: 26386981
[TBL] [Abstract][Full Text] [Related]
13. Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells.
Pan ST; Zhou J; Yang F; Zhou SF; Ren T
BMC Cancer; 2020 Jul; 20(1):634. PubMed ID: 32641008
[TBL] [Abstract][Full Text] [Related]
14. Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase.
Kosnopfel C; Sinnberg T; Sauer B; Niessner H; Schmitt A; Makino E; Forschner A; Hailfinger S; Garbe C; Schittek B
Oncotarget; 2017 May; 8(22):35761-35775. PubMed ID: 28415756
[TBL] [Abstract][Full Text] [Related]
15. Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes.
Stathopoulou K; Schobesberger S; Bork NI; Sprenger JU; Perera RK; Sotoud H; Geertz B; David JP; Christ T; Nikolaev VO; Cuello F
Cell Signal; 2019 Nov; 63():109362. PubMed ID: 31344438
[TBL] [Abstract][Full Text] [Related]
16. XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells.
Teng X; Fan XF; Li Q; Liu S; Wu DY; Wang SY; Shi Y; Dong M
Oncol Rep; 2019 Mar; 41(3):1875-1882. PubMed ID: 30628719
[TBL] [Abstract][Full Text] [Related]
17. Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1).
Reipas KM; Law JH; Couto N; Islam S; Li Y; Li H; Cherkasov A; Jung K; Cheema AS; Jones SJ; Hassell JA; Dunn SE
Oncotarget; 2013 Feb; 4(2):329-45. PubMed ID: 23593654
[TBL] [Abstract][Full Text] [Related]
18. Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway.
Kochetkova EY; Blinova GI; Bystrova OA; Martynova MG; Pospelov VA; Pospelova TV
Aging (Albany NY); 2017 Nov; 9(11):2352-2375. PubMed ID: 29140794
[TBL] [Abstract][Full Text] [Related]
19. BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells.
Lian G; Li L; Shi Y; Jing C; Liu J; Guo X; Zhang Q; Dai T; Ye F; Wang Y; Chen M
Int J Oncol; 2018 Mar; 52(3):804-814. PubMed ID: 29393385
[TBL] [Abstract][Full Text] [Related]
20. p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis.
Theodosakis N; Micevic G; Langdon CG; Ventura A; Means R; Stern DF; Bosenberg MW
J Invest Dermatol; 2017 Oct; 137(10):2187-2196. PubMed ID: 28599981
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
