BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 32667798)

  • 1. Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors.
    Robles O; Jackson JJ; Marshall L; Talay O; Chian D; Cutler G; Diokno R; Hu DX; Jacobson S; Karbarz E; Kassner PD; Ketcham JM; McKinnell J; Meleza C; Reilly MK; Riegler E; Shunatona HP; Wadsworth A; Younai A; Brockstedt DG; Wustrow DJ; Zibinsky M
    J Med Chem; 2020 Aug; 63(15):8584-8607. PubMed ID: 32667798
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tumors establish resistance to immunotherapy by regulating T
    Marshall LA; Marubayashi S; Jorapur A; Jacobson S; Zibinsky M; Robles O; Hu DX; Jackson JJ; Pookot D; Sanchez J; Brovarney M; Wadsworth A; Chian D; Wustrow D; Kassner PD; Cutler G; Wong B; Brockstedt DG; Talay O
    J Immunother Cancer; 2020 Nov; 8(2):. PubMed ID: 33243932
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T
    Jackson JJ; Ketcham JM; Younai A; Abraham B; Biannic B; Beck HP; Bui MHT; Chian D; Cutler G; Diokno R; Hu DX; Jacobson S; Karbarz E; Kassner PD; Marshall L; McKinnell J; Meleza C; Okal A; Pookot D; Reilly MK; Robles O; Shunatona HP; Talay O; Walker JR; Wadsworth A; Wustrow DJ; Zibinsky M
    J Med Chem; 2019 Jul; 62(13):6190-6213. PubMed ID: 31259550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A CCR4 antagonist enhances DC activation and homing to the regional lymph node and shows potent vaccine adjuvant activity through the inhibition of regulatory T-cell recruitment.
    Yamamoto S; Matsuo K; Nagakubo D; Higashiyama S; Nishiwaki K; Oiso N; Kawada A; Yoshie O; Nakayama T
    J Pharmacol Sci; 2018 Mar; 136(3):165-171. PubMed ID: 29519579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target?
    Ohue Y; Nishikawa H
    Cancer Sci; 2019 Jul; 110(7):2080-2089. PubMed ID: 31102428
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CCR4 Blockade Depletes Regulatory T Cells and Prolongs Survival in a Canine Model of Bladder Cancer.
    Maeda S; Murakami K; Inoue A; Yonezawa T; Matsuki N
    Cancer Immunol Res; 2019 Jul; 7(7):1175-1187. PubMed ID: 31160277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CCR4 Antagonists Inhibit T
    Ketcham JM; Marshall LA; Talay O
    ACS Med Chem Lett; 2018 Oct; 9(10):953-955. PubMed ID: 30344896
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination.
    Bayry J; Tchilian EZ; Davies MN; Forbes EK; Draper SJ; Kaveri SV; Hill AV; Kazatchkine MD; Beverley PC; Flower DR; Tough DF
    Proc Natl Acad Sci U S A; 2008 Jul; 105(29):10221-6. PubMed ID: 18621704
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma.
    Sun W; Li WJ; Wei FQ; Wong TS; Lei WB; Zhu XL; Li J; Wen WP
    Oncotarget; 2016 Jun; 7(25):37714-37727. PubMed ID: 27177223
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epstein-Barr virus-positive pyothorax-associated lymphoma expresses CCL17 and CCL22 chemokines that attract CCR4-expressing regulatory T cells.
    Higuchi T; Matsuo K; Hashida Y; Kitahata K; Ujihara T; Taniguchi A; Yoshie O; Nakayama T; Daibata M
    Cancer Lett; 2019 Jul; 453():184-192. PubMed ID: 30953706
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Foxp3
    Maeda S; Nakazawa M; Uchida M; Yoshitake R; Nakagawa T; Nishimura R; Miyamoto R; Bonkobara M; Yonezawa T; Momoi Y
    Vet Pathol; 2020 Jul; 57(4):497-506. PubMed ID: 32347186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Humanization of an anti-CCR4 antibody that kills cutaneous T-cell lymphoma cells and abrogates suppression by T-regulatory cells.
    Chang DK; Sui J; Geng S; Muvaffak A; Bai M; Fuhlbrigge RC; Lo A; Yammanuru A; Hubbard L; Sheehan J; Campbell JJ; Zhu Q; Kupper TS; Marasco WA
    Mol Cancer Ther; 2012 Nov; 11(11):2451-61. PubMed ID: 22869555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis.
    Hagemann UB; Gunnarsson L; GĂ©raudie S; Scheffler U; Griep RA; Reiersen H; Duncan AR; Kiprijanov SM
    PLoS One; 2014; 9(7):e103776. PubMed ID: 25080123
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical Application of Anti-CCR4 Monoclonal Antibody.
    Ueda R
    Oncology; 2015; 89 Suppl 1():16-21. PubMed ID: 26550987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dosing optimization of CCR4 immunotoxin for improved depletion of CCR4
    Wang Z; Louras NJ; Lellouch AG; Pratts SG; Zhang H; Wang H; Huang CA; Cetrulo CL; Madsen JC; Sachs DH; Wang Z
    Mol Oncol; 2018 Aug; 12(8):1374-1382. PubMed ID: 29873181
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-CCR4 treatment depletes regulatory T cells and leads to clinical activity in a canine model of advanced prostate cancer.
    Maeda S; Motegi T; Iio A; Kaji K; Goto-Koshino Y; Eto S; Ikeda N; Nakagawa T; Nishimura R; Yonezawa T; Momoi Y
    J Immunother Cancer; 2022 Feb; 10(2):. PubMed ID: 35131860
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.
    Pere H; Montier Y; Bayry J; Quintin-Colonna F; Merillon N; Dransart E; Badoual C; Gey A; Ravel P; Marcheteau E; Batteux F; Sandoval F; Adotevi O; Chiu C; Garcia S; Tanchot C; Lone YC; Ferreira LC; Nelson BH; Hanahan D; Fridman WH; Johannes L; Tartour E
    Blood; 2011 Nov; 118(18):4853-62. PubMed ID: 21908423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients.
    Kurose K; Ohue Y; Wada H; Iida S; Ishida T; Kojima T; Doi T; Suzuki S; Isobe M; Funakoshi T; Kakimi K; Nishikawa H; Udono H; Oka M; Ueda R; Nakayama E
    Clin Cancer Res; 2015 Oct; 21(19):4327-36. PubMed ID: 26429981
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Anti-CCR4 mAb and regulatory T cells].
    Kurose K; Ohue Y; Oka M
    Gan To Kagaku Ryoho; 2013 Sep; 40(9):1150-5. PubMed ID: 24047773
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin.
    Wang Z; Pratts SG; Zhang H; Spencer PJ; Yu R; Tonsho M; Shah JA; Tanabe T; Powell HR; Huang CA; Madsen JC; Sachs DH; Wang Z
    Mol Oncol; 2016 Apr; 10(4):553-65. PubMed ID: 26643572
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.