These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 32668192)

  • 1. TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.
    O'Leary EM; Tian Y; Nigdelioglu R; Witt LJ; Cetin-Atalay R; Meliton AY; Woods PS; Kimmig LM; Sun KA; Gökalp GA; Mutlu GM; Hamanaka RB
    Am J Respir Cell Mol Biol; 2020 Nov; 63(5):601-612. PubMed ID: 32668192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β
    Selvarajah B; Azuelos I; Platé M; Guillotin D; Forty EJ; Contento G; Woodcock HV; Redding M; Taylor A; Brunori G; Durrenberger PF; Ronzoni R; Blanchard AD; Mercer PF; Anastasiou D; Chambers RC
    Sci Signal; 2019 May; 12(582):. PubMed ID: 31113850
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATF4 and mTOR regulate metabolic reprogramming in TGF-β-treated lung fibroblasts.
    Shin KWD; Atalay MV; Cetin-Atalay R; O'Leary EM; Glass ME; Szafran JCH; Woods PS; Meliton AY; Shamaa OR; Tian Y; Mutlu GM; Hamanaka RB
    bioRxiv; 2024 Jun; ():. PubMed ID: 38915485
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Novel mTOR Complex 1/2 Inhibitor P529 Inhibits Human Lung Myofibroblast Differentiation.
    Ferguson KT; Torr EE; Bernau K; Leet J; Sherris D; Sandbo N
    J Cell Biochem; 2017 Aug; 118(8):2241-2249. PubMed ID: 28078713
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.
    Rahimi RA; Andrianifahanana M; Wilkes MC; Edens M; Kottom TJ; Blenis J; Leof EB
    Cancer Res; 2009 Jan; 69(1):84-93. PubMed ID: 19117990
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway.
    Saito S; Zhuang Y; Shan B; Danchuk S; Luo F; Korfei M; Guenther A; Lasky JA
    PLoS One; 2017; 12(10):e0186615. PubMed ID: 29045477
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A critical role for the mTORC2 pathway in lung fibrosis.
    Chang W; Wei K; Ho L; Berry GJ; Jacobs SS; Chang CH; Rosen GD
    PLoS One; 2014; 9(8):e106155. PubMed ID: 25162417
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals.
    Torrence ME; MacArthur MR; Hosios AM; Valvezan AJ; Asara JM; Mitchell JR; Manning BD
    Elife; 2021 Mar; 10():. PubMed ID: 33646118
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anoctamin-1 is induced by TGF-β and contributes to lung myofibroblast differentiation.
    Reed EB; Orbeta S; Miao BA; Sitikov A; Chen B; Levitan I; Solway J; Mutlu GM; Fang Y; Mongin AA; Dulin NO
    Am J Physiol Lung Cell Mol Physiol; 2024 Jan; 326(1):L111-L123. PubMed ID: 38084409
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial One-Carbon Metabolism is Required for TGF-β-Induced Glycine Synthesis and Collagen Protein Production.
    Meliton AY; Cetin-Atalay R; Tian Y; Szafran JCH; Shin KWD; Cho T; Sun KA; Woods PS; Shamaa OR; Chen B; Muir A; Mutlu GM; Hamanaka RB
    bioRxiv; 2023 Nov; ():. PubMed ID: 37986788
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.
    Woodcock HV; Eley JD; Guillotin D; Platé M; Nanthakumar CB; Martufi M; Peace S; Joberty G; Poeckel D; Good RB; Taylor AR; Zinn N; Redding M; Forty EJ; Hynds RE; Swanton C; Karsdal M; Maher TM; Fisher A; Bergamini G; Marshall RP; Blanchard AD; Mercer PF; Chambers RC
    Nat Commun; 2019 Jan; 10(1):6. PubMed ID: 30602778
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapamycin inhibits transforming growth factor beta 1 induced myofibroblast differentiation via the phosphorylated-phosphatidylinositol 3-kinase mammalian target of rapamycin signal pathways in nasal polyp-derived fibroblasts.
    Ko DY; Shin JM; Um JY; Kang B; Park IH; Lee HM
    Am J Rhinol Allergy; 2016 Nov; 30(6):211-217. PubMed ID: 28124643
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transforming growth factor β suppresses osteoblast differentiation via the vimentin activating transcription factor 4 (ATF4) axis.
    Lian N; Lin T; Liu W; Wang W; Li L; Sun S; Nyman JS; Yang X
    J Biol Chem; 2012 Oct; 287(43):35975-84. PubMed ID: 22952236
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
    Hamanaka RB; Nigdelioglu R; Meliton AY; Tian Y; Witt LJ; O'Leary E; Sun KA; Woods PS; Wu D; Ansbro B; Ard S; Rohde JM; Dulin NO; Guzy RD; Mutlu GM
    Am J Respir Cell Mol Biol; 2018 May; 58(5):585-593. PubMed ID: 29019702
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI3K signaling mediates diverse regulation of ATF4 expression for the survival of HK-2 cells exposed to cadmium.
    Fujiki K; Inamura H; Matsuoka M
    Arch Toxicol; 2014 Feb; 88(2):403-14. PubMed ID: 24057571
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis.
    Hu X; Xu Q; Wan H; Hu Y; Xing S; Yang H; Gao Y; He Z
    Lab Invest; 2020 Jun; 100(6):801-811. PubMed ID: 32051533
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production.
    Nigdelioglu R; Hamanaka RB; Meliton AY; O'Leary E; Witt LJ; Cho T; Sun K; Bonham C; Wu D; Woods PS; Husain AN; Wolfgeher D; Dulin NO; Chandel NS; Mutlu GM
    J Biol Chem; 2016 Dec; 291(53):27239-27251. PubMed ID: 27836973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TGF-β/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1α expression.
    Rozen-Zvi B; Hayashida T; Hubchak SC; Hanna C; Platanias LC; Schnaper HW
    Am J Physiol Renal Physiol; 2013 Aug; 305(4):F485-94. PubMed ID: 23761672
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resveratrol inhibits transforming growth factor-β-induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt inhibition and PTEN restoration.
    Fagone E; Conte E; Gili E; Fruciano M; Pistorio MP; Lo Furno D; Giuffrida R; Crimi N; Vancheri C
    Exp Lung Res; 2011 Apr; 37(3):162-74. PubMed ID: 21269063
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF.
    Bernard M; Dieudé M; Yang B; Hamelin K; Underwood K; Hébert MJ
    Autophagy; 2014; 10(12):2193-207. PubMed ID: 25495560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.