These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 3266830)

  • 1. Selectivity of CF and 5-fluorouracil: critical role of polyglutamylation.
    Houghton JA; Williams LG; deGraaf SS; Radparvar S; Wainer IW; Rodman JR; Houghton PJ
    Adv Exp Med Biol; 1988; 244():85-95. PubMed ID: 3266830
    [No Abstract]   [Full Text] [Related]  

  • 2. New therapeutic strategies for patients with gastrointestinal malignancies using biochemical modulation of fluorouracil.
    Allegra CJ
    JAMA; 1995 Jan; 273(3):236-9. PubMed ID: 7807664
    [No Abstract]   [Full Text] [Related]  

  • 3. The efficacy of 5-fluorouracil in human colorectal cancer is not enhanced by thymidylate synthetase inhibition with CB3717 (N10-propargyl-5,8 dideazafolic acid).
    Cantwell BM; Harris AL
    Br J Cancer; 1988 Aug; 58(2):189-90. PubMed ID: 3166908
    [No Abstract]   [Full Text] [Related]  

  • 4. Effect of leucovorin on 5-fluorouracil induced inhibition of thymidylate synthase in patients with colon cancer.
    Peters GJ; van Groeningen CJ; van der Wilt CL; Smid K; Meijer S; Pinedo HM
    Adv Exp Med Biol; 1991; 309A():131-4. PubMed ID: 1789191
    [No Abstract]   [Full Text] [Related]  

  • 5. Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft.
    Radparvar S; Houghton PJ; Houghton JA
    Biochem Pharmacol; 1989 Jan; 38(2):335-42. PubMed ID: 2914018
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characteristics of thymidylate synthase purified from a human colon adenocarcinoma.
    Radparvar S; Houghton PJ; Houghton JA
    Arch Biochem Biophys; 1988 Jan; 260(1):342-50. PubMed ID: 3341747
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo.
    Kase S; Kubota T; Watanabe M; Takahara T; Takeuchi T; Yamaguchi H; Furukawa T; Teramoto T; Kodaira S; Ishibiki K
    Surg Today; 1993; 23(7):615-20. PubMed ID: 8369613
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.
    Fernandes DJ; Bertino JR
    Proc Natl Acad Sci U S A; 1980 Oct; 77(10):5663-7. PubMed ID: 6160578
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacodynamics of 5-fluorouracil and leucovorin.
    Gustavsson BG; Carlsson G; Frösing R; Spears CP
    Adv Exp Med Biol; 1988; 244():219-24. PubMed ID: 3266824
    [No Abstract]   [Full Text] [Related]  

  • 11. Thymidylate synthetase activity and fluorouracil sensitivity of human colonic cancer and normal mucosal tissue preparations.
    Wolberg WH; Morin J
    Cancer; 1981 Mar; 47(6):1313-7. PubMed ID: 7226054
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vivo antitumor effects of fluoropyrimidines on colon adenocarcinoma 38 and enhancement by leucovorin.
    Iigo M; Nishikata K; Hoshi A
    Jpn J Cancer Res; 1992 Apr; 83(4):392-6. PubMed ID: 1387127
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
    Fernandes DJ; Moroson BA; Bertino JR
    Cancer Treat Rep; 1981; 65 Suppl 1():29-35. PubMed ID: 6173121
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil.
    Spears CP; Gustavsson BG; Berne M; Frösing R; Bernstein L; Hayes AA
    Cancer Res; 1988 Oct; 48(20):5894-900. PubMed ID: 3167844
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of continuous infusions and bolus injections of 5-fluorouracil with or without leucovorin: implications for inhibition of thymidylate synthase.
    Peters GJ; Codacci-Pisanelli G; van der Wilt CL; van Laar JA; Smid K; Noordhuis P; Pinedo HM
    Adv Exp Med Biol; 1993; 339():9-20; discussion 21. PubMed ID: 8178733
    [No Abstract]   [Full Text] [Related]  

  • 16. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
    Spears CP; Shahinian AH; Moran RG; Heidelberger C; Corbett TH
    Cancer Res; 1982 Feb; 42(2):450-6. PubMed ID: 6173112
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cell cycle patterns of thymidylate synthetase and 5,10-methylenetetrahydrofolate polyglutamates in cultured mouse hepatoma cells.
    Priest DG; Doig MT; Ledford BE
    Experientia; 1982 Jan; 38(1):88-9. PubMed ID: 7056367
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin.
    Romanini A; Lin JT; Niedzwiecki D; Bunni M; Priest DG; Bertino JR
    Cancer Res; 1991 Feb; 51(3):789-93. PubMed ID: 1988119
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates.
    Houghton PJ; Rahman A; Will CL; Dolnick BJ; Houghton JA
    Cancer Res; 1992 Feb; 52(3):558-65. PubMed ID: 1732043
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual modulation by l-leucovorin and recombinant human interferon alpha 2a of 5-fluorouracil antitumor activity against the human colon carcinoma xenograft Co-4.
    Kase S; Kubota T; Watanabe M; Furukawa T; Tanino H; Kuo TH; Saikawa Y; Teramoto T; Kitajima M
    J Interferon Cytokine Res; 1995 Dec; 15(12):1089-93. PubMed ID: 8746791
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.