BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 32673563)

  • 1. G
    Coyne AN; Zaepfel BL; Hayes L; Fitchman B; Salzberg Y; Luo EC; Bowen K; Trost H; Aigner S; Rigo F; Yeo GW; Harel A; Svendsen CN; Sareen D; Rothstein JD
    Neuron; 2020 Sep; 107(6):1124-1140.e11. PubMed ID: 32673563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.
    Wang SM; Wu HE; Yasui Y; Geva M; Hayden M; Maurice T; Cozzolino M; Su TP
    Autophagy; 2023 Jan; 19(1):126-151. PubMed ID: 35507432
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei.
    Coyne AN; Rothstein JD
    Acta Neuropathol Commun; 2021 Jul; 9(1):127. PubMed ID: 34281622
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stress Granule Assembly Disrupts Nucleocytoplasmic Transport.
    Zhang K; Daigle JG; Cunningham KM; Coyne AN; Ruan K; Grima JC; Bowen KE; Wadhwa H; Yang P; Rigo F; Taylor JP; Gitler AD; Rothstein JD; Lloyd TE
    Cell; 2018 May; 173(4):958-971.e17. PubMed ID: 29628143
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient.
    Lee J; Park J; Kim JH; Lee G; Park TE; Yoon KJ; Kim YK; Lim C
    PLoS Biol; 2020 Dec; 18(12):e3001002. PubMed ID: 33362237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models.
    Yuva-Aydemir Y; Almeida S; Gao FB
    Trends Neurosci; 2018 Jul; 41(7):457-469. PubMed ID: 29729808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
    Chou CC; Zhang Y; Umoh ME; Vaughan SW; Lorenzini I; Liu F; Sayegh M; Donlin-Asp PG; Chen YH; Duong DM; Seyfried NT; Powers MA; Kukar T; Hales CM; Gearing M; Cairns NJ; Boylan KB; Dickson DW; Rademakers R; Zhang YJ; Petrucelli L; Sattler R; Zarnescu DC; Glass JD; Rossoll W
    Nat Neurosci; 2018 Feb; 21(2):228-239. PubMed ID: 29311743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS.
    Coyne AN; Baskerville V; Zaepfel BL; Dickson DW; Rigo F; Bennett F; Lusk CP; Rothstein JD
    Sci Transl Med; 2021 Jul; 13(604):. PubMed ID: 34321318
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
    Zhang K; Donnelly CJ; Haeusler AR; Grima JC; Machamer JB; Steinwald P; Daley EL; Miller SJ; Cunningham KM; Vidensky S; Gupta S; Thomas MA; Hong I; Chiu SL; Huganir RL; Ostrow LW; Matunis MJ; Wang J; Sattler R; Lloyd TE; Rothstein JD
    Nature; 2015 Sep; 525(7567):56-61. PubMed ID: 26308891
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.
    Ortega JA; Daley EL; Kour S; Samani M; Tellez L; Smith HS; Hall EA; Esengul YT; Tsai YH; Gendron TF; Donnelly CJ; Siddique T; Savas JN; Pandey UB; Kiskinis E
    Neuron; 2020 Apr; 106(1):90-107.e13. PubMed ID: 32059759
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
    Ramesh N; Daley EL; Gleixner AM; Mann JR; Kour S; Mawrie D; Anderson EN; Kofler J; Donnelly CJ; Kiskinis E; Pandey UB
    Acta Neuropathol Commun; 2020 Oct; 8(1):177. PubMed ID: 33129345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.
    Moore S; Alsop E; Lorenzini I; Starr A; Rabichow BE; Mendez E; Levy JL; Burciu C; Reiman R; Chew J; Belzil VV; W Dickson D; Robertson J; Staats KA; Ichida JK; Petrucelli L; Van Keuren-Jensen K; Sattler R
    Acta Neuropathol; 2019 Jul; 138(1):49-65. PubMed ID: 30945056
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SUN1 facilitates CHMP7 nuclear influx and injury cascades in sporadic amyotrophic lateral sclerosis.
    Baskerville V; Rapuri S; Mehlhop E; Coyne AN
    Brain; 2024 Jan; 147(1):109-121. PubMed ID: 37639327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD.
    Yuva-Aydemir Y; Almeida S; Krishnan G; Gendron TF; Gao FB
    Nat Commun; 2019 Nov; 10(1):5466. PubMed ID: 31784536
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction.
    Perkins EM; Burr K; Banerjee P; Mehta AR; Dando O; Selvaraj BT; Suminaite D; Nanda J; Henstridge CM; Gillingwater TH; Hardingham GE; Wyllie DJA; Chandran S; Livesey MR
    Mol Neurodegener; 2021 Mar; 16(1):13. PubMed ID: 33663561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The progress in
    Jiang L; Zhang T; Lu K; Qi S
    Small GTPases; 2022 Jan; 13(1):56-76. PubMed ID: 33663328
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
    Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
    Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD.
    Fallini C; Khalil B; Smith CL; Rossoll W
    Neurobiol Dis; 2020 Jul; 140():104835. PubMed ID: 32179176
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear lamina invaginations are not a pathological feature of C9orf72 ALS/FTD.
    Coyne AN; Rothstein JD
    Acta Neuropathol Commun; 2021 Mar; 9(1):45. PubMed ID: 33741069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.