283 related articles for article (PubMed ID: 32673568)
1. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Tovy A; Reyes JM; Gundry MC; Brunetti L; Lee-Six H; Petljak M; Park HJ; Guzman AG; Rosas C; Jeffries AR; Baple E; Mill J; Crosby AH; Sency V; Xin B; Machado HE; Castillo D; Weitzel JN; Li W; Stratton MR; Campbell PJ; Wang H; Sanders MA; Goodell MA
Cell Stem Cell; 2020 Aug; 27(2):326-335.e4. PubMed ID: 32673568
[TBL] [Abstract][Full Text] [Related]
2. Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling.
Hormaechea-Agulla D; Matatall KA; Le DT; Kain B; Long X; Kus P; Jaksik R; Challen GA; Kimmel M; King KY
Cell Stem Cell; 2021 Aug; 28(8):1428-1442.e6. PubMed ID: 33743191
[TBL] [Abstract][Full Text] [Related]
3. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.
Jeong M; Park HJ; Celik H; Ostrander EL; Reyes JM; Guzman A; Rodriguez B; Lei Y; Lee Y; Ding L; Guryanova OA; Li W; Goodell MA; Challen GA
Cell Rep; 2018 Apr; 23(1):1-10. PubMed ID: 29617651
[TBL] [Abstract][Full Text] [Related]
4. Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21.
Zhang CR; Ostrander EL; Kukhar O; Mallaney C; Sun J; Haussler E; Celik H; Koh WK; King KY; Gontarz P; Challen GA
Blood Cancer Discov; 2022 May; 3(3):220-239. PubMed ID: 35394496
[TBL] [Abstract][Full Text] [Related]
5. Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders.
Midic D; Rinke J; Perner F; Müller V; Hinze A; Pester F; Landschulze J; Ernst J; Gruhn B; Matziolis G; Heidel FH; Hochhaus A; Ernst T
Leukemia; 2020 Aug; 34(8):2198-2205. PubMed ID: 32457355
[TBL] [Abstract][Full Text] [Related]
6. Heterozygous Dnmt3a R878C induces expansion of quiescent hematopoietic stem cell pool.
Higo T; Suzuki Y; Sato M; Koya J; Mizuno H; Miyauchi M; Masamoto Y; Kataoka K; Sumitomo Y; Tsuruta-Kishino T; Sato T; Kurokawa M
Exp Hematol; 2022 May; 109():45-54. PubMed ID: 35245608
[TBL] [Abstract][Full Text] [Related]
7. Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation.
Cypris O; Franzen J; Frobel J; Glück P; Kuo CC; Schmitz S; Nüchtern S; Zenke M; Wagner W
BMC Biol; 2022 Jun; 20(1):141. PubMed ID: 35705990
[TBL] [Abstract][Full Text] [Related]
8. Dnmt3a-null hematopoietic stem and progenitor cells expand after busulfan treatment.
Chen J; Matatall KA; Feng X; Hormaechea-Agulla D; Maharjan M; Young N; King KY
Exp Hematol; 2020 Nov; 91():39-45.e2. PubMed ID: 32961298
[TBL] [Abstract][Full Text] [Related]
9. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
Rau RE; Rodriguez BA; Luo M; Jeong M; Rosen A; Rogers JH; Campbell CT; Daigle SR; Deng L; Song Y; Sweet S; Chevassut T; Andreeff M; Kornblau SM; Li W; Goodell MA
Blood; 2016 Aug; 128(7):971-81. PubMed ID: 27335278
[TBL] [Abstract][Full Text] [Related]
10. Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome.
Tovy A; Rosas C; Gaikwad AS; Medrano G; Zhang L; Reyes JM; Huang YH; Arakawa T; Kurtz K; Conneely SE; Guzman AG; Aguilar R; Gao A; Chen CW; Kim JJ; Carter MT; Lasa-Aranzasti A; Valenzuela I; Van Maldergem L; Brunetti L; Hicks MJ; Marcogliese AN; Goodell MA; Rau RE
Haematologica; 2022 Apr; 107(4):887-898. PubMed ID: 34092059
[TBL] [Abstract][Full Text] [Related]
11. Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
Smith AM; LaValle TA; Shinawi M; Ramakrishnan SM; Abel HJ; Hill CA; Kirkland NM; Rettig MP; Helton NM; Heath SE; Ferraro F; Chen DY; Adak S; Semenkovich CF; Christian DL; Martin JR; Gabel HW; Miller CA; Ley TJ
Nat Commun; 2021 Jul; 12(1):4549. PubMed ID: 34315901
[TBL] [Abstract][Full Text] [Related]
12. Alterations to
Venugopal K; Feng Y; Shabashvili D; Guryanova OA
Cancer Res; 2021 Jan; 81(2):254-263. PubMed ID: 33087320
[TBL] [Abstract][Full Text] [Related]
13. Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis.
Loberg MA; Bell RK; Goodwin LO; Eudy E; Miles LA; SanMiguel JM; Young K; Bergstrom DE; Levine RL; Schneider RK; Trowbridge JJ
Leukemia; 2019 Jul; 33(7):1635-1649. PubMed ID: 30692594
[TBL] [Abstract][Full Text] [Related]
14. Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Nam AS; Dusaj N; Izzo F; Murali R; Myers RM; Mouhieddine TH; Sotelo J; Benbarche S; Waarts M; Gaiti F; Tahri S; Levine R; Abdel-Wahab O; Godley LA; Chaligne R; Ghobrial I; Landau DA
Nat Genet; 2022 Oct; 54(10):1514-1526. PubMed ID: 36138229
[TBL] [Abstract][Full Text] [Related]
15. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
Yang L; Rodriguez B; Mayle A; Park HJ; Lin X; Luo M; Jeong M; Curry CV; Kim SB; Ruau D; Zhang X; Zhou T; Zhou M; Rebel VI; Challen GA; Gottgens B; Lee JS; Rau R; Li W; Goodell MA
Cancer Cell; 2016 Jun; 29(6):922-934. PubMed ID: 27300438
[TBL] [Abstract][Full Text] [Related]
16. [Functional role of DNMT3A mutation in acute myeloid leukemia].
Koya J; Kurokawa M
Rinsho Ketsueki; 2018; 59(5):602-610. PubMed ID: 29877252
[TBL] [Abstract][Full Text] [Related]
17. Sowing the Seeds of Clonal Hematopoiesis.
Liggett LA; Voit RA; Sankaran VG
Cell Stem Cell; 2020 Aug; 27(2):195-197. PubMed ID: 32763180
[TBL] [Abstract][Full Text] [Related]
18. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis.
Zhang X; Wang X; Wang XQD; Su J; Putluri N; Zhou T; Qu Y; Jeong M; Guzman A; Rosas C; Huang Y; Sreekumar A; Li W; Goodell MA
Blood; 2020 Mar; 135(11):845-856. PubMed ID: 31932841
[TBL] [Abstract][Full Text] [Related]
19. Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.
Zioni N; Bercovich AA; Chapal-Ilani N; Bacharach T; Rappoport N; Solomon A; Avraham R; Kopitman E; Porat Z; Sacma M; Hartmut G; Scheller M; Muller-Tidow C; Lipka D; Shlush E; Minden M; Kaushansky N; Shlush LI
Nat Commun; 2023 Apr; 14(1):2070. PubMed ID: 37045808
[TBL] [Abstract][Full Text] [Related]
20. DNMT3A mutations in acute myeloid leukemia.
Shah MY; Licht JD
Nat Genet; 2011 Mar; 43(4):289-90. PubMed ID: 21445072
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
