BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

432 related articles for article (PubMed ID: 32673658)

  • 1. Pyridoxal isonicotinoyl hydrazone inhibition of FXR is involved in the pathogenesis of isoniazid-induced liver injury.
    Zhang G; Chen L; Wen Y; Rao Z; Wei Y; Wu X
    Toxicol Appl Pharmacol; 2020 Sep; 402():115134. PubMed ID: 32673658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells.
    Qu X; Zhang Y; Zhang S; Zhai J; Gao H; Tao L; Song Y
    Biol Pharm Bull; 2018; 41(8):1211-1218. PubMed ID: 30068870
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
    Gao X; Fu T; Wang C; Ning C; Liu K; Liu Z; Sun H; Ma X; Huo X; Yang X; Zou M; Meng Q
    Toxicol Appl Pharmacol; 2018 Jun; 348():105-116. PubMed ID: 29660435
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of the farnesoid X receptor in quadruple anti-tuberculosis drug-induced liver injury.
    Wen Y; Zhang G; Wu X
    Toxicology; 2022 Jun; 476():153256. PubMed ID: 35835356
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis.
    Brewer CT; Yang L; Edwards A; Lu Y; Low J; Wu J; Lee RE; Chen T
    Toxicol Sci; 2019 Mar; 168(1):209-224. PubMed ID: 30517741
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation.
    Xiong X; Ren Y; Cui Y; Li R; Wang C; Zhang Y
    Biomed Pharmacother; 2017 Dec; 96():1292-1298. PubMed ID: 29174575
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative potency of obeticholic acid and natural bile acids on FXR in hepatic and intestinal in vitro cell models.
    Zhang Y; LaCerte C; Kansra S; Jackson JP; Brouwer KR; Edwards JE
    Pharmacol Res Perspect; 2017 Dec; 5(6):. PubMed ID: 29226620
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.
    Meng Q; Chen XL; Wang CY; Liu Q; Sun HJ; Sun PY; Huo XK; Liu ZH; Yao JH; Liu KX
    Toxicol Appl Pharmacol; 2015 Mar; 283(3):178-86. PubMed ID: 25655198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FXR agonist GW4064 improves liver and intestinal pathology and alters bile acid metabolism in rats undergoing small intestinal resection.
    Cao Y; Xiao Y; Zhou K; Yan J; Wang P; Yan W; Cai W
    Am J Physiol Gastrointest Liver Physiol; 2019 Aug; 317(2):G108-G115. PubMed ID: 30920307
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport.
    Guo HL; Hassan HM; Zhang Y; Dong SZ; Ding PP; Wang T; Sun LX; Zhang LY; Jiang ZZ
    Toxicol Sci; 2016 Aug; 152(2):417-28. PubMed ID: 27255380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The inhibition of hepatic bile acids transporters Ntcp and Bsep is involved in the pathogenesis of isoniazid/rifampicin-induced hepatotoxicity.
    Guo YX; Xu XF; Zhang QZ; Li C; Deng Y; Jiang P; He LY; Peng WX
    Toxicol Mech Methods; 2015; 25(5):382-7. PubMed ID: 25886055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice.
    Zhang H; Wen M; Chen J; Yao C; Lin X; Lin Z; Ru J; Zhuge Q; Yang S
    Biomed Res Int; 2021; 2021():9916328. PubMed ID: 34541001
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
    Pineda Torra I; Claudel T; Duval C; Kosykh V; Fruchart JC; Staels B
    Mol Endocrinol; 2003 Feb; 17(2):259-72. PubMed ID: 12554753
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis.
    Bechmann LP; Kocabayoglu P; Sowa JP; Sydor S; Best J; Schlattjan M; Beilfuss A; Schmitt J; Hannivoort RA; Kilicarslan A; Rust C; Berr F; Tschopp O; Gerken G; Friedman SL; Geier A; Canbay A
    Hepatology; 2013 Apr; 57(4):1394-406. PubMed ID: 23299969
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.
    Li X; Liu R; Yu L; Yuan Z; Sun R; Yang H; Zhang L; Jiang Z
    Toxicology; 2016 Aug; 370():106-115. PubMed ID: 27702592
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes.
    Lee KK; Fujimoto K; Zhang C; Schwall CT; Alder NN; Pinkert CA; Krueger W; Rasmussen T; Boelsterli UA
    Free Radic Biol Med; 2013 Dec; 65():584-594. PubMed ID: 23911619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of in vivo iron chelation by pyridoxal isonicotinoyl hydrazone and other imino derivatives of pyridoxal.
    Hershko C; Avramovici-Grisaru S; Link G; Gelfand L; Sarel S
    J Lab Clin Med; 1981 Jul; 98(1):99-108. PubMed ID: 7252329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bile acids, lipid and purine metabolism involved in hepatotoxicity of first-line anti-tuberculosis drugs.
    Liu L; Li X; Huang C; Bian Y; Liu X; Cao J; Qu W; Miao L
    Expert Opin Drug Metab Toxicol; 2020 Jun; 16(6):527-537. PubMed ID: 32436768
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition.
    Vaquero J; Monte MJ; Dominguez M; Muntané J; Marin JJ
    Biochem Pharmacol; 2013 Oct; 86(7):926-39. PubMed ID: 23928191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hesperidin alleviates cholestasis via activation of the farnesoid X receptor in vitro and in vivo.
    Zhang G; Sun X; Wen Y; Shi A; Zhang J; Wei Y; Wu X
    Eur J Pharmacol; 2020 Oct; 885():173498. PubMed ID: 32841642
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.