189 related articles for article (PubMed ID: 32675407)
1. Glutamine Antagonist JHU-083 Normalizes Aberrant Hippocampal Glutaminase Activity and Improves Cognition in APOE4 Mice.
Hollinger KR; Zhu X; Khoury ES; Thomas AG; Liaw K; Tallon C; Wu Y; Prchalova E; Kamiya A; Rojas C; Kannan S; Slusher BS
J Alzheimers Dis; 2020; 77(1):437-447. PubMed ID: 32675407
[TBL] [Abstract][Full Text] [Related]
2. Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders.
Nedelcovych MT; Kim BH; Zhu X; Lovell LE; Manning AA; Kelschenbach J; Hadas E; Chao W; Prchalová E; Dash RP; Wu Y; Alt J; Thomas AG; Rais R; Kamiya A; Volsky DJ; Slusher BS
J Neuroimmune Pharmacol; 2019 Sep; 14(3):391-400. PubMed ID: 31209775
[TBL] [Abstract][Full Text] [Related]
3. Glutamine antagonism attenuates physical and cognitive deficits in a model of MS.
Hollinger KR; Smith MD; Kirby LA; Prchalova E; Alt J; Rais R; Calabresi PA; Slusher BS
Neurol Neuroimmunol Neuroinflamm; 2019 Nov; 6(6):. PubMed ID: 31467038
[TBL] [Abstract][Full Text] [Related]
4. Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome.
Khoury ES; Sharma A; Ramireddy RR; Thomas AG; Alt J; Fowler A; Rais R; Tsukamoto T; Blue ME; Slusher B; Kannan S; Kannan RM
Theranostics; 2020; 10(13):5736-5748. PubMed ID: 32483415
[No Abstract] [Full Text] [Related]
5. Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice.
Ophir G; Meilin S; Efrati M; Chapman J; Karussis D; Roses A; Michaelson DM
Neurobiol Dis; 2003 Feb; 12(1):56-64. PubMed ID: 12609489
[TBL] [Abstract][Full Text] [Related]
6. A mouse model of chemotherapy-related cognitive impairments integrating the risk factors of aging and APOE4 genotype.
Demby TC; Rodriguez O; McCarthy CW; Lee YC; Albanese C; Mandelblatt J; Rebeck GW
Behav Brain Res; 2020 Apr; 384():112534. PubMed ID: 32027870
[TBL] [Abstract][Full Text] [Related]
7. JHU-083 selectively blocks glutaminase activity in brain CD11b
Zhu X; Nedelcovych MT; Thomas AG; Hasegawa Y; Moreno-Megui A; Coomer W; Vohra V; Saito A; Perez G; Wu Y; Alt J; Prchalova E; Tenora L; Majer P; Rais R; Rojas C; Slusher BS; Kamiya A
Neuropsychopharmacology; 2019 Mar; 44(4):683-694. PubMed ID: 30127344
[TBL] [Abstract][Full Text] [Related]
8. APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.
Liu DS; Pan XD; Zhang J; Shen H; Collins NC; Cole AM; Koster KP; Ben Aissa M; Dai XM; Zhou M; Tai LM; Zhu YG; LaDu M; Chen XC
Mol Neurodegener; 2015 Mar; 10():7. PubMed ID: 25871877
[TBL] [Abstract][Full Text] [Related]
9. Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice.
Dolejší E; Liraz O; Rudajev V; Zimčík P; Doležal V; Michaelson DM
J Neurochem; 2016 Feb; 136(3):503-9. PubMed ID: 26526158
[TBL] [Abstract][Full Text] [Related]
10. ApoE4-dependent Abeta-mediated neurodegeneration is associated with inflammatory activation in the hippocampus but not the septum.
Belinson H; Michaelson DM
J Neural Transm (Vienna); 2009 Nov; 116(11):1427-34. PubMed ID: 19370389
[TBL] [Abstract][Full Text] [Related]
11. Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology.
Koren-Iton A; Salomon-Zimri S; Smolar A; Shavit-Stein E; Dori A; Chapman J; Michaelson DM
Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32075060
[TBL] [Abstract][Full Text] [Related]
12. Development of a Human APOE Knock-in Mouse Model for Study of Cognitive Function After Cancer Chemotherapy.
Speidell AP; Demby T; Lee Y; Rodriguez O; Albanese C; Mandelblatt J; Rebeck GW
Neurotox Res; 2019 Feb; 35(2):291-303. PubMed ID: 30284204
[TBL] [Abstract][Full Text] [Related]
13. Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice.
Engstrom AK; Snyder JM; Maeda N; Xia Z
Mol Neurodegener; 2017 Feb; 12(1):14. PubMed ID: 28173832
[TBL] [Abstract][Full Text] [Related]
14. PKR Inhibition Rescues Memory Deficit and ATF4 Overexpression in ApoE ε4 Human Replacement Mice.
Segev Y; Barrera I; Ounallah-Saad H; Wibrand K; Sporild I; Livne A; Rosenberg T; David O; Mints M; Bramham CR; Rosenblum K
J Neurosci; 2015 Sep; 35(38):12986-93. PubMed ID: 26400930
[TBL] [Abstract][Full Text] [Related]
15. ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.
Liraz O; Boehm-Cagan A; Michaelson DM
Mol Neurodegener; 2013 May; 8():16. PubMed ID: 23684315
[TBL] [Abstract][Full Text] [Related]
16. Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate.
Wu B; Liu J; Zhao R; Li Y; Peer J; Braun AL; Zhao L; Wang Y; Tong Z; Huang Y; Zheng JC
J Neuroinflammation; 2018 Mar; 15(1):79. PubMed ID: 29540215
[TBL] [Abstract][Full Text] [Related]
17. Small molecule glutaminase inhibitors block glutamate release from stimulated microglia.
Thomas AG; O'Driscoll CM; Bressler J; Kaufmann W; Rojas CJ; Slusher BS
Biochem Biophys Res Commun; 2014 Jan; 443(1):32-6. PubMed ID: 24269238
[TBL] [Abstract][Full Text] [Related]
18. Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples.
Gillespie AK; Jones EA; Lin YH; Karlsson MP; Kay K; Yoon SY; Tong LM; Nova P; Carr JS; Frank LM; Huang Y
Neuron; 2016 May; 90(4):740-51. PubMed ID: 27161522
[TBL] [Abstract][Full Text] [Related]
19. Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E.
Kitamura HW; Hamanaka H; Watanabe M; Wada K; Yamazaki C; Fujita SC; Manabe T; Nukina N
Neurosci Lett; 2004 Oct; 369(3):173-8. PubMed ID: 15464259
[TBL] [Abstract][Full Text] [Related]
20. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]