These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 32675848)

  • 1. TRIGGERING ANAPHASE CATASTROPHE TO COMBAT ANEUPLOID CANCERS.
    Dmitrovsky E; Kawakami M; Liu XI; Freemantle SJ; Kurie JM
    Trans Am Clin Climatol Assoc; 2020; 131():82-94. PubMed ID: 32675848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers.
    Kawakami M; Mustachio LM; Liu X; Dmitrovsky E
    Mol Cancer Ther; 2018 Apr; 17(4):724-731. PubMed ID: 29559545
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.
    Hu S; Danilov AV; Godek K; Orr B; Tafe LJ; Rodriguez-Canales J; Behrens C; Mino B; Moran CA; Memoli VA; Mustachio LM; Galimberti F; Ravi S; DeCastro A; Lu Y; Sekula D; Andrew AS; Wistuba II; Freemantle S; Compton DA; Dmitrovsky E
    Cancer Res; 2015 May; 75(10):2029-38. PubMed ID: 25808870
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers.
    Kawakami M; Mustachio LM; Chen Y; Chen Z; Liu X; Wei CH; Roszik J; Kittai AS; Danilov AV; Zhang X; Fang B; Wang J; Heymach JV; Tyutyunyk-Massey L; Freemantle SJ; Kurie JM; Liu X; Dmitrovsky E
    Mol Cancer Ther; 2021 Mar; 20(3):477-489. PubMed ID: 33277443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown.
    Hu S; Lu Y; Orr B; Godek K; Mustachio LM; Kawakami M; Sekula D; Compton DA; Freemantle S; Dmitrovsky E
    Mol Cancer Ther; 2015 Nov; 14(11):2576-85. PubMed ID: 26304236
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells.
    Chen Z; Liu X; Kawakami M; Liu X; Baker A; Bhatawadekar A; Tyutyunyk-Massey L; Narayan K; Dmitrovsky E
    Cancer Biol Ther; 2023 Dec; 24(1):2279241. PubMed ID: 38031910
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer.
    Kawakami M; Mustachio LM; Rodriguez-Canales J; Mino B; Roszik J; Tong P; Wang J; Lee JJ; Myung JH; Heymach JV; Johnson FM; Hong S; Zheng L; Hu S; Villalobos PA; Behrens C; Wistuba I; Freemantle S; Liu X; Dmitrovsky E
    J Natl Cancer Inst; 2017 Jun; 109(6):. PubMed ID: 28376145
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anaphase catastrophe is a target for cancer therapy.
    Galimberti F; Thompson SL; Ravi S; Compton DA; Dmitrovsky E
    Clin Cancer Res; 2011 Mar; 17(6):1218-22. PubMed ID: 21288923
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2.
    Danilov AV; Hu S; Orr B; Godek K; Mustachio LM; Sekula D; Liu X; Kawakami M; Johnson FM; Compton DA; Freemantle SJ; Dmitrovsky E
    Mol Cancer Ther; 2016 Nov; 15(11):2758-2766. PubMed ID: 27550941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes.
    Navarro-Serer B; Childers EP; Hermance NM; Mercadante D; Manning AL
    Oncotarget; 2019 Feb; 10(17):1649-1659. PubMed ID: 30899434
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A p27Kip1 mutant that does not inhibit CDK activity promotes centrosome amplification and micronucleation.
    Sharma SS; Ma L; Bagui TK; Forinash KD; Pledger WJ
    Oncogene; 2012 Aug; 31(35):3989-98. PubMed ID: 22158041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mechanism linking extra centrosomes to chromosomal instability.
    Ganem NJ; Godinho SA; Pellman D
    Nature; 2009 Jul; 460(7252):278-82. PubMed ID: 19506557
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.
    Koo CY; Giacomini C; Reyes-Corral M; Olmos Y; Tavares IA; Marson CM; Linardopoulos S; Tutt AN; Morris JDH
    Mol Cancer Ther; 2017 Nov; 16(11):2410-2421. PubMed ID: 28830982
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
    Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells.
    McDermott KM; Zhang J; Holst CR; Kozakiewicz BK; Singla V; Tlsty TD
    PLoS Biol; 2006 Mar; 4(3):e51. PubMed ID: 16464125
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe.
    Galimberti F; Thompson SL; Liu X; Li H; Memoli V; Green SR; DiRenzo J; Greninger P; Sharma SV; Settleman J; Compton DA; Dmitrovsky E
    Clin Cancer Res; 2010 Jan; 16(1):109-20. PubMed ID: 20028770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.
    Kawakami M; Mustachio LM; Zheng L; Chen Y; Rodriguez-Canales J; Mino B; Kurie JM; Roszik J; Villalobos PA; Thu KL; Silvester J; Cescon DW; Wistuba II; Mak TW; Liu X; Dmitrovsky E
    Proc Natl Acad Sci U S A; 2018 Feb; 115(8):1913-1918. PubMed ID: 29434041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer.
    Lingle WL; Lukasiewicz K; Salisbury JL
    Adv Exp Med Biol; 2005; 570():393-421. PubMed ID: 18727509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells.
    Castiel A; Visochek L; Mittelman L; Dantzer F; Izraeli S; Cohen-Armon M
    BMC Cancer; 2011 Sep; 11():412. PubMed ID: 21943092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events.
    De Boer L; Oakes V; Beamish H; Giles N; Stevens F; Somodevilla-Torres M; Desouza C; Gabrielli B
    Oncogene; 2008 Jul; 27(31):4261-8. PubMed ID: 18372919
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.