177 related articles for article (PubMed ID: 32677906)
1. Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q; Bian X; Liu X; Wang Y; Zhou H; Ma X; Quan C; Yao Y; Zheng Z
BMC Cancer; 2020 Jul; 20(1):665. PubMed ID: 32677906
[TBL] [Abstract][Full Text] [Related]
2. Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy.
Changou CA; Chen YR; Xing L; Yen Y; Chuang FY; Cheng RH; Bold RJ; Ann DK; Kung HJ
Proc Natl Acad Sci U S A; 2014 Sep; 111(39):14147-52. PubMed ID: 25122679
[TBL] [Abstract][Full Text] [Related]
3. Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis.
Kim RH; Coates JM; Bowles TL; McNerney GP; Sutcliffe J; Jung JU; Gandour-Edwards R; Chuang FY; Bold RJ; Kung HJ
Cancer Res; 2009 Jan; 69(2):700-8. PubMed ID: 19147587
[TBL] [Abstract][Full Text] [Related]
4. Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.
Kuo MT; Savaraj N; Feun LG
Oncotarget; 2010 Aug; 1(4):246-51. PubMed ID: 21152246
[TBL] [Abstract][Full Text] [Related]
5. Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells.
Qiu F; Chen YR; Liu X; Chu CY; Shen LJ; Xu J; Gaur S; Forman HJ; Zhang H; Zheng S; Yen Y; Huang J; Kung HJ; Ann DK
Sci Signal; 2014 Apr; 7(319):ra31. PubMed ID: 24692592
[TBL] [Abstract][Full Text] [Related]
6. Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase.
Bowles TL; Kim R; Galante J; Parsons CM; Virudachalam S; Kung HJ; Bold RJ
Int J Cancer; 2008 Oct; 123(8):1950-5. PubMed ID: 18661517
[TBL] [Abstract][Full Text] [Related]
7. Chromatophagy: autophagy goes nuclear and captures broken chromatin during arginine-starvation.
Kung HJ; Changou CA; Li CF; Ann DK
Autophagy; 2015; 11(2):419-21. PubMed ID: 25650867
[TBL] [Abstract][Full Text] [Related]
8. Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis.
Delage B; Luong P; Maharaj L; O'Riain C; Syed N; Crook T; Hatzimichael E; Papoudou-Bai A; Mitchell TJ; Whittaker SJ; Cerio R; Gribben J; Lemoine N; Bomalaski J; Li CF; Joel S; Fitzgibbon J; Chen LT; Szlosarek PW
Cell Death Dis; 2012 Jul; 3(7):e342. PubMed ID: 22764101
[TBL] [Abstract][Full Text] [Related]
9. Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation.
Singh PK; Deorukhkar AA; Venkatesulu BP; Li X; Tailor R; Bomalaski JS; Krishnan S
Mol Cancer Ther; 2019 Dec; 18(12):2381-2393. PubMed ID: 31395686
[TBL] [Abstract][Full Text] [Related]
10. Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.
Jiang H; Guo S; Xiao D; Bian X; Wang J; Wang Y; Zhou H; Cai J; Zheng Z
Oncotarget; 2017 Jun; 8(23):37694-37704. PubMed ID: 28455966
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).
Burrows N; Cane G; Robson M; Gaude E; Howat WJ; Szlosarek PW; Pedley RB; Frezza C; Ashcroft M; Maxwell PH
Sci Rep; 2016 Mar; 6():22950. PubMed ID: 26972697
[TBL] [Abstract][Full Text] [Related]
12. Arginine deprivation as a targeted therapy for cancer.
Feun L; You M; Wu CJ; Kuo MT; Wangpaichitr M; Spector S; Savaraj N
Curr Pharm Des; 2008; 14(11):1049-57. PubMed ID: 18473854
[TBL] [Abstract][Full Text] [Related]
13. Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
Savaraj N; You M; Wu C; Wangpaichitr M; Kuo MT; Feun LG
Curr Mol Med; 2010 Jun; 10(4):405-12. PubMed ID: 20459375
[TBL] [Abstract][Full Text] [Related]
14. Amino Acid Uptake Measured by [
Prudner BC; Sun F; Kremer JC; Xu J; Huang C; Sai KKS; Morgan Z; Leeds H; McConathy J; Van Tine BA
Theranostics; 2018; 8(8):2107-2116. PubMed ID: 29721066
[No Abstract] [Full Text] [Related]
15. Mono-PEGylated thermostable Bacillus caldovelox arginase mutant (BCA-M-PEG20) induces apoptosis, autophagy, cell cycle arrest and growth inhibition in gastric cancer cells.
Chung SF; Tam SY; Kim CF; Chong HC; Lee LM; Leung YC
Invest New Drugs; 2022 Oct; 40(5):895-904. PubMed ID: 35857203
[TBL] [Abstract][Full Text] [Related]
16. The role of arginine and the modified arginine deiminase enzyme ADI-PEG 20 in cancer therapy with special emphasis on Phase I/II clinical trials.
Synakiewicz A; Stachowicz-Stencel T; Adamkiewicz-Drozynska E
Expert Opin Investig Drugs; 2014 Nov; 23(11):1517-29. PubMed ID: 24965808
[TBL] [Abstract][Full Text] [Related]
17. Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin.
Savaraj N; Wu C; Li YY; Wangpaichitr M; You M; Bomalaski J; He W; Kuo MT; Feun LG
Oncotarget; 2015 Mar; 6(8):6295-309. PubMed ID: 25749046
[TBL] [Abstract][Full Text] [Related]
18. The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma.
Thongkum A; Wu C; Li YY; Wangpaichitr M; Navasumrit P; Parnlob V; Sricharunrat T; Bhudhisawasdi V; Ruchirawat M; Savaraj N
Int J Mol Sci; 2017 Jun; 18(6):. PubMed ID: 28587170
[TBL] [Abstract][Full Text] [Related]
19. Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma.
Wu C; You M; Nguyen D; Wangpaichitr M; Li YY; Feun LG; Kuo MT; Savaraj N
Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299249
[TBL] [Abstract][Full Text] [Related]
20. A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas.
Bean GR; Kremer JC; Prudner BC; Schenone AD; Yao JC; Schultze MB; Chen DY; Tanas MR; Adkins DR; Bomalaski J; Rubin BP; Michel LS; Van Tine BA
Cell Death Dis; 2016 Oct; 7(10):e2406. PubMed ID: 27735949
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
