These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 32687187)

  • 1. Enhancement of target specificity of CRISPR-Cas12a by using a chimeric DNA-RNA guide.
    Kim H; Lee WJ; Oh Y; Kang SH; Hur JK; Lee H; Song W; Lim KS; Park YH; Song BS; Jin YB; Jun BH; Jung C; Lee DS; Kim SU; Lee SH
    Nucleic Acids Res; 2020 Sep; 48(15):8601-8616. PubMed ID: 32687187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a.
    Strohkendl I; Saifuddin FA; Rybarski JR; Finkelstein IJ; Russell R
    Mol Cell; 2018 Sep; 71(5):816-824.e3. PubMed ID: 30078724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The bridge helix of Cas12a imparts selectivity in cis-DNA cleavage and regulates trans-DNA cleavage.
    Parameshwaran HP; Babu K; Tran C; Guan K; Allen A; Kathiresan V; Qin PZ; Rajan R
    FEBS Lett; 2021 Apr; 595(7):892-912. PubMed ID: 33523494
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects.
    Murugan K; Seetharam AS; Severin AJ; Sashital DG
    J Biol Chem; 2020 Apr; 295(17):5538-5553. PubMed ID: 32161115
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
    Swarts DC; Jinek M
    Mol Cell; 2019 Feb; 73(3):589-600.e4. PubMed ID: 30639240
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene Manipulation Using Fusion Guide RNAs for Cas9 and Cas12a.
    Shin HR; Kweon J; Kim Y
    Methods Mol Biol; 2021; 2162():185-193. PubMed ID: 32926383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a.
    Swartjes T; Staals RHJ; van der Oost J
    Biochem Soc Trans; 2020 Feb; 48(1):207-219. PubMed ID: 31872209
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Survey of Genome Editing Activity for 16 Cas12a Orthologs.
    Zetsche B; Abudayyeh OO; Gootenberg JS; Scott DA; Zhang F
    Keio J Med; 2020 Sep; 69(3):59-65. PubMed ID: 31723075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a).
    Singh D; Mallon J; Poddar A; Wang Y; Tippana R; Yang O; Bailey S; Ha T
    Proc Natl Acad Sci U S A; 2018 May; 115(21):5444-5449. PubMed ID: 29735714
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a.
    Creutzburg SCA; Wu WY; Mohanraju P; Swartjes T; Alkan F; Gorodkin J; Staals RHJ; van der Oost J
    Nucleic Acids Res; 2020 Apr; 48(6):3228-3243. PubMed ID: 31989168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene Disruption Using Chemically Modified CRISPR-Cpf1 RNA.
    McMahon MA; Rahdar M
    Methods Mol Biol; 2021; 2162():49-60. PubMed ID: 32926377
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
    Swarts DC; van der Oost J; Jinek M
    Mol Cell; 2017 Apr; 66(2):221-233.e4. PubMed ID: 28431230
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Harnessing noncanonical crRNA for highly efficient genome editing.
    Xun G; Zhu Z; Singh N; Lu J; Jain PK; Zhao H
    Nat Commun; 2024 May; 15(1):3823. PubMed ID: 38714643
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems.
    Zhang Y; Ren Q; Tang X; Liu S; Malzahn AA; Zhou J; Wang J; Yin D; Pan C; Yuan M; Huang L; Yang H; Zhao Y; Fang Q; Zheng X; Tian L; Cheng Y; Le Y; McCoy B; Franklin L; Selengut JD; Mount SM; Que Q; Zhang Y; Qi Y
    Nat Commun; 2021 Mar; 12(1):1944. PubMed ID: 33782402
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct observation of DNA target searching and cleavage by CRISPR-Cas12a.
    Jeon Y; Choi YH; Jang Y; Yu J; Goo J; Lee G; Jeong YK; Lee SH; Kim IS; Kim JS; Jeong C; Lee S; Bae S
    Nat Commun; 2018 Jul; 9(1):2777. PubMed ID: 30018371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
    Yamano T; Zetsche B; Ishitani R; Zhang F; Nishimasu H; Nureki O
    Mol Cell; 2017 Aug; 67(4):633-645.e3. PubMed ID: 28781234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiplexed conditional genome editing with Cas12a in
    Port F; Starostecka M; Boutros M
    Proc Natl Acad Sci U S A; 2020 Sep; 117(37):22890-22899. PubMed ID: 32843348
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and Evaluation of Guide RNA Transcripts with a 3'-Terminal HDV Ribozyme to Enhance CRISPR-Based Gene Inactivation.
    Berkhout B; Gao Z; Herrera-Carrillo E
    Methods Mol Biol; 2021; 2167():205-224. PubMed ID: 32712922
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mg
    Son H; Park J; Hwang I; Jung Y; Bae S; Lee S
    Proc Natl Acad Sci U S A; 2021 Dec; 118(49):. PubMed ID: 34853172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a.
    Liu W; Tang D; Wang H; Lian J; Huang L; Xu Z
    Appl Microbiol Biotechnol; 2019 Nov; 103(21-22):8911-8922. PubMed ID: 31583448
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.