These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. SETD2 as a regulator of N6-methyladenosine RNA methylation and modifiers in cancer. Kumari S; Muthusamy S Eur J Cancer Prev; 2020 Nov; 29(6):556-564. PubMed ID: 33021769 [TBL] [Abstract][Full Text] [Related]
23. De novo heterozygous missense and loss-of-function variants in CDC42BPB are associated with a neurodevelopmental phenotype. Chilton I; Okur V; Vitiello G; Selicorni A; Mariani M; Goldenberg A; Husson T; Campion D; Lichtenbelt KD; van Gassen K; Steinraths M; Rice J; Roeder ER; Littlejohn RO; Srour M; Sebire G; Accogli A; Héron D; Heide S; Nava C; Depienne C; Larson A; Niyazov D; Azage M; Hoganson G; Burton J; Rush ET; Jenkins JL; Saunders CJ; Thiffault I; Alaimo JT; Fleischer J; Groepper D; Gripp KW; Chung WK Am J Med Genet A; 2020 May; 182(5):962-973. PubMed ID: 32031333 [TBL] [Abstract][Full Text] [Related]
24. De Novo and Inherited Loss-of-Function Variants in TLK2: Clinical and Genotype-Phenotype Evaluation of a Distinct Neurodevelopmental Disorder. Reijnders MRF; Miller KA; Alvi M; Goos JAC; Lees MM; de Burca A; Henderson A; Kraus A; Mikat B; de Vries BBA; Isidor B; Kerr B; Marcelis C; Schluth-Bolard C; Deshpande C; Ruivenkamp CAL; Wieczorek D; ; Baralle D; Blair EM; Engels H; Lüdecke HJ; Eason J; Santen GWE; Clayton-Smith J; Chandler K; Tatton-Brown K; Payne K; Helbig K; Radtke K; Nugent KM; Cremer K; Strom TM; Bird LM; Sinnema M; Bitner-Glindzicz M; van Dooren MF; Alders M; Koopmans M; Brick L; Kozenko M; Harline ML; Klaassens M; Steinraths M; Cooper NS; Edery P; Yap P; Terhal PA; van der Spek PJ; Lakeman P; Taylor RL; Littlejohn RO; Pfundt R; Mercimek-Andrews S; Stegmann APA; Kant SG; McLean S; Joss S; Swagemakers SMA; Douzgou S; Wall SA; Küry S; Calpena E; Koelling N; McGowan SJ; Twigg SRF; Mathijssen IMJ; Nellaker C; Brunner HG; Wilkie AOM Am J Hum Genet; 2018 Jun; 102(6):1195-1203. PubMed ID: 29861108 [TBL] [Abstract][Full Text] [Related]
25. Expanded phenotypic spectrum of neurodevelopmental and neurodegenerative disorder Bryant-Li-Bhoj syndrome with 38 additional individuals. Layo-Carris DE; Lubin EE; Sangree AK; Clark KJ; Durham EL; Gonzalez EM; Smith S; Angireddy R; Wang XM; Weiss E; Toutain A; Mendoza-Londono R; Dupuis L; Damseh N; Velasco D; Valenzuela I; Codina-Solà M; Ziats C; Have J; Clarkson K; Steel D; Kurian M; Barwick K; Carrasco D; Dagli AI; Nowaczyk MJM; Hančárová M; Bendová Š; Prchalova D; Sedláček Z; Baxová A; Nowak CB; Douglas J; Chung WK; Longo N; Platzer K; Klöckner C; Averdunk L; Wieczorek D; Krey I; Zweier C; Reis A; Balci T; Simon M; Kroes HY; Wiesener A; Vasileiou G; Marinakis NM; Veltra D; Sofocleous C; Kosma K; Traeger Synodinos J; Voudris KA; Vuillaume ML; Gueguen P; Derive N; Colin E; Battault C; Au B; Delatycki M; Wallis M; Gallacher L; Majdoub F; Smal N; Weckhuysen S; Schoonjans AS; Kooy RF; Meuwissen M; Cocanougher BT; Taylor K; Pizoli CE; McDonald MT; James P; Roeder ER; Littlejohn R; Borja NA; Thorson W; King K; Stoeva R; Suerink M; Nibbeling E; Baskin S; L E Guyader G; Kaplan J; Muss C; Carere DA; Bhoj EJK; Bryant LM Eur J Hum Genet; 2024 Aug; 32(8):928-937. PubMed ID: 38678163 [TBL] [Abstract][Full Text] [Related]
26. De novo missense variants in HDAC3 leading to epigenetic machinery dysfunction are associated with a variable neurodevelopmental disorder. Yoon JG; Lim SK; Seo H; Lee S; Cho J; Kim SY; Koh HY; Poduri AH; Ramakumaran V; Vasudevan P; de Groot MJ; Ko JM; Han D; Chae JH; Lee CH Am J Hum Genet; 2024 Aug; 111(8):1588-1604. PubMed ID: 39047730 [TBL] [Abstract][Full Text] [Related]
27. Expansion of the Genotypic and Phenotypic Spectrum of Cordova I; Blesson A; Savatt JM; Sveden A; Mahida S; Hazlett H; Rooney Riggs E; Chopra M; Genes (Basel); 2024 Mar; 15(4):. PubMed ID: 38674358 [TBL] [Abstract][Full Text] [Related]
28. Expanding the phenotype of Wiedemann-Steiner syndrome: Craniovertebral junction anomalies. Giangiobbe S; Caraffi SG; Ivanovski I; Maini I; Pollazzon M; Rosato S; Trimarchi G; Lauriello A; Marinelli M; Nicoli D; Baldo C; Laurie S; Flores-Daboub J; Provenzano A; Andreucci E; Peluso F; Rizzo R; Stewart H; Lachlan K; Bayat A; Napoli M; Carboni G; Baker J; Mendel A; Piatelli G; Pantaleoni C; Mattina T; Prontera P; Mendelsohn NJ; Giglio S; Zuffardi O; Garavelli L Am J Med Genet A; 2020 Dec; 182(12):2877-2886. PubMed ID: 33043602 [TBL] [Abstract][Full Text] [Related]
29. Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome. Kummeling J; Stremmelaar DE; Raun N; Reijnders MRF; Willemsen MH; Ruiterkamp-Versteeg M; Schepens M; Man CCO; Gilissen C; Cho MT; McWalter K; Sinnema M; Wheless JW; Simon MEH; Genetti CA; Casey AM; Terhal PA; van der Smagt JJ; van Gassen KLI; Joset P; Bahr A; Steindl K; Rauch A; Keller E; Raas-Rothschild A; Koolen DA; Agrawal PB; Hoffman TL; Powell-Hamilton NN; Thiffault I; Engleman K; Zhou D; Bodamer O; Hoefele J; Riedhammer KM; Schwaibold EMC; Tasic V; Schubert D; Top D; Pfundt R; Higgs MR; Kramer JM; Kleefstra T Mol Psychiatry; 2021 Jun; 26(6):2013-2024. PubMed ID: 32346159 [TBL] [Abstract][Full Text] [Related]
30. SETD2 alterations and histone H3K36 trimethylation in phyllodes tumor of breast. Tsang JY; Lai ST; Ni YB; Shao Y; Poon IK; Kwan JS; Chow C; Shea KH; Tse GM Breast Cancer Res Treat; 2021 Jun; 187(2):339-347. PubMed ID: 33844099 [TBL] [Abstract][Full Text] [Related]
31. SETD2 histone modifier loss in aggressive GI stromal tumours. Huang KK; McPherson JR; Tay ST; Das K; Tan IB; Ng CC; Chia NY; Zhang SL; Myint SS; Hu L; Rajasegaran V; Huang D; Loh JL; Gan A; Sairi AN; Sam XX; Dominguez LT; Lee M; Soo KC; Ooi LL; Ong HS; Chung A; Chow PK; Wong WK; Selvarajan S; Ong CK; Lim KH; Nandi T; Rozen S; Teh BT; Quek R; Tan P Gut; 2016 Dec; 65(12):1960-1972. PubMed ID: 26338826 [TBL] [Abstract][Full Text] [Related]
32. The histone methyltransferase Setd2 is indispensable for V(D)J recombination. Ji Z; Sheng Y; Miao J; Li X; Zhao H; Wang J; Cheng C; Wang X; Liu K; Zhang K; Xu L; Yao J; Shen L; Hou J; Zhou W; Sun J; Li L; Gao WQ; Zhu HH Nat Commun; 2019 Jul; 10(1):3353. PubMed ID: 31350389 [TBL] [Abstract][Full Text] [Related]
33. A clustering of heterozygous missense variants in the crucial chromatin modifier WDR5 defines a new neurodevelopmental disorder. Snijders Blok L; Verseput J; Rots D; Venselaar H; Innes AM; Stumpel C; Õunap K; Reinson K; Seaby EG; McKee S; Burton B; Kim K; van Hagen JM; Waisfisz Q; Joset P; Steindl K; Rauch A; Li D; Zackai EH; Sheppard SE; Keena B; Hakonarson H; Roos A; Kohlschmidt N; Cereda A; Iascone M; Rebessi E; Kernohan KD; Campeau PM; Millan F; Taylor JA; Lochmüller H; Higgs MR; Goula A; Bernhard B; Velasco DJ; Schmanski AA; Stark Z; Gallacher L; Pais L; Marcogliese PC; Yamamoto S; Raun N; Jakub TE; Kramer JM; den Hoed J; Fisher SE; Brunner HG; Kleefstra T HGG Adv; 2023 Jan; 4(1):100157. PubMed ID: 36408368 [TBL] [Abstract][Full Text] [Related]
34. SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle. Gautam D; Johnson BA; Mac M; Moody CA PLoS Pathog; 2018 Oct; 14(10):e1007367. PubMed ID: 30312361 [TBL] [Abstract][Full Text] [Related]
35. H4C5 missense variant leads to a neurodevelopmental phenotype overlapping with Angelman syndrome. Borja N; Borjas-Mendoza P; Bivona S; Peart L; Gonzalez J; Johnson BK; Guo S; Yusupov R; ; Bademci G; Tekin M Am J Med Genet A; 2023 Jul; 191(7):1911-1916. PubMed ID: 36987712 [TBL] [Abstract][Full Text] [Related]
36. SETD2: an epigenetic modifier with tumor suppressor functionality. Li J; Duns G; Westers H; Sijmons R; van den Berg A; Kok K Oncotarget; 2016 Aug; 7(31):50719-50734. PubMed ID: 27191891 [TBL] [Abstract][Full Text] [Related]
37. Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations. Rees E; Creeth HDJ; Hwu HG; Chen WJ; Tsuang M; Glatt SJ; Rey R; Kirov G; Walters JTR; Holmans P; Owen MJ; O'Donovan MC Nat Commun; 2021 Sep; 12(1):5353. PubMed ID: 34504065 [TBL] [Abstract][Full Text] [Related]
38. Brief Report: SETD2 Mutation in a Child with Autism, Intellectual Disabilities and Epilepsy. Lumish HS; Wynn J; Devinsky O; Chung WK J Autism Dev Disord; 2015 Nov; 45(11):3764-70. PubMed ID: 26084711 [TBL] [Abstract][Full Text] [Related]