BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 32715755)

  • 21. Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics.
    Koessinger AL; Cloix C; Koessinger D; Heiland DH; Bock FJ; Strathdee K; Kinch K; Martínez-Escardó L; Paul NR; Nixon C; Malviya G; Jackson MR; Campbell KJ; Stevenson K; Davis S; Elmasry Y; Ahmed A; O'Prey J; Ichim G; Schnell O; Stewart W; Blyth K; Ryan KM; Chalmers AJ; Norman JC; Tait SWG
    Cell Death Differ; 2022 Oct; 29(10):2089-2104. PubMed ID: 35473984
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker.
    Richard DJ; Lena R; Bannister T; Blake N; Pierceall WE; Carlson NE; Keller CE; Koenig M; He Y; Minond D; Mishra J; Cameron M; Spicer T; Hodder P; Cardone MH
    Bioorg Med Chem; 2013 Nov; 21(21):6642-9. PubMed ID: 23993674
    [TBL] [Abstract][Full Text] [Related]  

  • 23. EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.
    Nalluri S; Peirce SK; Tanos R; Abdella HA; Karmali D; Hogarty MD; Goldsmith KC
    Cancer Biol Ther; 2015; 16(2):276-86. PubMed ID: 25756510
    [TBL] [Abstract][Full Text] [Related]  

  • 24. BH3 mimetics induce apoptosis independent of DRP-1 in melanoma.
    Mukherjee N; Strosnider A; Vagher B; Lambert KA; Slaven S; Robinson WA; Amato CM; Couts KL; Bemis JGT; Turner JA; Norris DA; Shellman YG
    Cell Death Dis; 2018 Sep; 9(9):907. PubMed ID: 30185782
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML.
    Ewald L; Dittmann J; Vogler M; Fulda S
    Cell Death Dis; 2019 Dec; 10(12):917. PubMed ID: 31801941
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance.
    Shahar N; Larisch S
    Drug Resist Updat; 2020 Sep; 52():100712. PubMed ID: 32599435
    [TBL] [Abstract][Full Text] [Related]  

  • 27. BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells.
    Reinhart R; Rohner L; Wicki S; Fux M; Kaufmann T
    Cell Death Differ; 2018 Jan; 25(1):204-216. PubMed ID: 28960207
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Differential Expression of Bcl-2 Family Proteins Determines the Sensitivity of Human Follicular Lymphoma Cells to Dexamethasone-mediated and Anti-BCR-mediated Apoptosis.
    Adem J; Ropponen A; Eeva J; Eray M; Nuutinen U; Pelkonen J
    J Immunother; 2016 Jan; 39(1):8-14. PubMed ID: 26641257
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia.
    Iacovelli S; Ricciardi MR; Allegretti M; Mirabilii S; Licchetta R; Bergamo P; Rinaldo C; Zeuner A; Foà R; Milella M; McCubrey JA; Martelli AM; Tafuri A
    Oncotarget; 2015 Oct; 6(31):32089-103. PubMed ID: 26392332
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Current overview on the clinical update of Bcl-2 anti-apoptotic inhibitors for cancer therapy.
    Suvarna V; Singh V; Murahari M
    Eur J Pharmacol; 2019 Nov; 862():172655. PubMed ID: 31494078
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The novel small molecular BH3 mimetics SM3 and its regulation of cell apoptosis and autophagy.
    Wang Y; Fan S; Li X; Xiaokaiti Y; Pan Y; Tie L; Li X
    Biochem Biophys Res Commun; 2019 Sep; 517(1):15-22. PubMed ID: 31303271
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cell Death Pathways in Lymphoid Malignancies.
    Fletcher L; Nabrinsky E; Liu T; Danilov A
    Curr Oncol Rep; 2020 Jan; 22(1):10. PubMed ID: 31989308
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling.
    Peperzak V; Slinger E; Ter Burg J; Eldering E
    Cell Death Differ; 2017 Jan; 24(1):111-119. PubMed ID: 27689871
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations.
    Henz K; Al-Zebeeby A; Basoglu M; Fulda S; Cohen GM; Varadarajan S; Vogler M
    Biol Chem; 2019 Jan; 400(2):181-185. PubMed ID: 29924730
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rationally derived drug combinations with the novel Mcl-1 inhibitor EU-5346 in breast cancer.
    Vallet S; Fan F; Malvestiti S; Pecherstorfer M; Sattler M; Schneeweiss A; Schulze-Bergkamen H; Opferman JT; Cardone MH; Jäger D; Podar K
    Breast Cancer Res Treat; 2019 Feb; 173(3):585-596. PubMed ID: 30374681
    [TBL] [Abstract][Full Text] [Related]  

  • 36. BH3 mimetics inhibit growth of chondrosarcoma--a novel targeted-therapy for candidate models.
    Morii T; Ohtsuka K; Ohnishi H; Mochizuki K; Yoshiyama A; Aoyagi T; Hornicek FJ; Ichimura S
    Anticancer Res; 2014 Nov; 34(11):6423-30. PubMed ID: 25368242
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2.
    Liu Q; Osterlund EJ; Chi X; Pogmore J; Leber B; Andrews DW
    Elife; 2019 Mar; 8():. PubMed ID: 30860026
    [TBL] [Abstract][Full Text] [Related]  

  • 38. BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma.
    Ishida CT; Bianchetti E; Shu C; Halatsch ME; Westhoff MA; Karpel-Massler G; Siegelin MD
    Oncotarget; 2017 May; 8(18):29558-29573. PubMed ID: 28418907
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Patent landscape of inhibitors and PROTACs of the anti-apoptotic BCL-2 family proteins.
    Pal P; Zhang P; Poddar SK; Zheng G
    Expert Opin Ther Pat; 2022 Sep; 32(9):1003-1026. PubMed ID: 35993382
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis.
    Hlavac M; Dwucet A; Kast RE; Engelke J; Westhoff MA; Siegelin MD; Debatin KM; Wirtz CR; Halatsch ME; Karpel-Massler G
    Cell Oncol (Dordr); 2019 Jun; 42(3):287-301. PubMed ID: 30859392
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.